ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1N5Z2.PDB
Scoring matrix: 1N5Z2_mat
Uniprot code: P80667
Genome source: Saccharomyces cerevisiae
Wild-type ligand: MPPTLPHRDW
Foldx wt ligand score: 4.31
Foldx random average score for Saccharomyces cerevisiae: 14.702

Available information for P80667 in MINT (Nov 2008):
Nš of interacting proteins: 17
 Proteins belonging to other specie: 0
Nš of interactions described: 24
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 4413
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 2766
 Total fragments: 1058057
Proteins after random average filtering: 2766
 Total fragments: 515498
Proteins after disorder filtering: 1623
 Total fragments: 26996
Proteins after pattern filtering: 771
 Total fragments: 4932
Proteins after MINT filtering: 7
 Total fragments: 67


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

MPPTLPHRDW

4.31

-16.89

0.00

Best peptides

WMPRRPRRYW

0.00

-16.39

0.50

         
Interactors      
Q04370

EDIPRPPFSS

8.24

-12.70

4.19

PRPPFSSHSD

9.84

-11.18

5.71

DIPRPPFSSH

11.98

-7.04

9.85

P40450

VTPPAPPLPN

10.17

-9.41

7.48

SPKLFPRLSS

10.45

-9.15

7.74

APPPLPDLFK

10.46

-11.88

5.01

P47135

TPRASPSRSK

9.24

-8.44

8.45

LSPGQPLNAN

9.39

-8.18

8.71

PFPLPPPNVN

10.41

-9.26

7.63

P15274

PPPPKPSYNS

9.47

-11.05

5.84

VYPPPPKPSY

11.80

-10.05

6.84

NPKNKPGWVV

12.04

-10.29

6.60

P53112

SPNGIPGIDT

13.00

-5.78

11.11

ISPNGIPGID

14.26

-3.47

13.42

FSISPNGIPG

14.28

-5.23

11.66

Q08446

NNSSHSPISP

13.96

-4.50

12.39

Q12110

GSPVAPSPNH

12.42

-5.78

11.11

PVAPSPNHRS

13.73

-6.34

10.55

NSQGSPVAPS

14.56

-4.33

12.56

 


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