ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: NBP2_1GCQ-13.PDB
Scoring matrix: NBP2_1GCQ-13_mat
Uniprot code: Q12163
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 20.1
Foldx random average score for Saccharomyces cerevisiae: 14.940

Available information for Q12163 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 20
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1369833
Proteins after disorder filtering: 4294
 Total fragments: 50903
Proteins after pattern filtering: 1967
 Total fragments: 8578
Proteins after MINT filtering: 7
 Total fragments: 85


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

20.10

-1.71

0.00

Best peptides

RRRRFPRW

0.00

-12.59

-10.88

         
Interactors      
Q01389

SKPLPPQL

10.48

-5.70

-3.99

EPSTPSRP

10.99

-6.87

-5.16

KPLPPQLL

11.34

-6.75

-5.04

P53933

PPPLPNRQ

7.42

-9.04

-7.33

RPPPPPIP

8.43

-10.86

-9.15

RVAPPPLP

10.31

-9.46

-7.75

P53914

VKPLPPKE

10.23

-7.25

-5.54

LPPIDPKD

11.57

-5.10

-3.39

KNVKPLPP

13.05

-6.34

-4.63

P48562

SPLNPYRP

9.29

-6.97

-5.26

MRQAPKRP

9.40

-9.50

-7.79

NPYRPHHN

9.41

-7.31

-5.60

Q03497

GKFIPSRP

7.65

-8.39

-6.68

EQPLPPIP

10.29

-7.97

-6.26

APTTPNRT

10.60

-8.28

-6.57

P08018

RAPRRPLS

7.60

-12.47

-10.76

RPNVAPHK

9.36

-7.82

-6.11

HPTRPNVA

10.00

-7.70

-5.99

Q12469

ELKPFPRP

9.57

-6.10

-4.39

LKPFPRPS

12.99

-6.16

-4.45

RLAPSAPA

14.62

-4.87

-3.16

 


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