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Matrix information:
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ADAN-name: 4GBQ2.PDB
Scoring matrix: 4GBQ2_mat
Uniprot code: Q60631
Genome source: Mus musculus
Wild-type ligand: VPPPVPPRRR
Foldx wt ligand score: 1.85
Foldx random average score for Mus musculus: 11.797 Available information for Q60631 in MINT (Nov 2008):
Nš of interacting proteins: 32
Proteins belonging to other specie: 6
Nš of interactions described: 55
Interactions with other species: 12
Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
Total fragments: 20375566
Proteins after random average filtering: 44442
Total fragments: 10091215
Proteins after disorder filtering: 32059
Total fragments: 945519
Proteins after pattern filtering: 22855
Total fragments: 286500
Proteins after MINT filtering: 25
Total fragments: 699
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
VPPPVPPRRR |
1.85
|
-15.69 |
0.00 |
| Best peptides |
APPERPRNRR |
0.00
|
-10.76 |
4.93 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q62245 |
VPPPVPPRRR |
1.85
|
-13.61 |
2.08 |
|
PPPVPPRRRP |
5.01
|
-13.49 |
2.20 |
|
SPPAIPPRQP |
5.78
|
-13.39 |
2.30 |
| Q02384 |
IPPPLPPRKK |
4.55
|
-12.05 |
3.64 |
|
PAPPVPPRQN |
4.65
|
-13.96 |
1.73 |
|
PPPLPPRKKF |
4.69
|
-10.86 |
4.83 |
| P39054 |
IPPGVPSRRA |
3.12
|
-13.09 |
2.60 |
|
AAPSRPTIIR |
3.33
|
-12.25 |
3.44 |
|
HPPGRPPAVR |
4.29
|
-11.50 |
4.19 |
| P35991 |
KKPLPPEPTA |
7.55
|
-8.23 |
7.46 |
|
KKPLPPTPEE |
8.25
|
-7.07 |
8.62 |
|
PLPPTPEEDQ |
9.84
|
-5.51 |
10.18 |
| Q9Z1S8 |
PPPRPPKPSQ |
7.09
|
-8.82 |
6.87 |
|
PRPPKPSQAE |
7.16
|
-10.84 |
4.85 |
|
FQPGSPSPHR |
7.39
|
-7.34 |
8.35 |
| Q62077 |
DGPDGMPVIY |
10.45
|
-4.97 |
10.72 |
|
DCWDGPDGMP |
10.48
|
-4.53 |
11.16 |
| P70424 |
PPPIRPAGAT |
6.00
|
-10.61 |
5.08 |
|
CPPCAPTCKD |
6.05
|
-8.60 |
7.09 |
|
HPECQPQNSS |
6.28
|
-7.32 |
8.37 |
| Q8R550 |
PKKPRPPKTN |
5.05
|
-11.12 |
4.57 |
|
PPPSAPVVKQ |
6.37
|
-9.31 |
6.38 |
|
LPPKPGTMAA |
6.49
|
-8.10 |
7.59 |
| Q923U0 |
LPSSHPVLKD |
7.29
|
-7.64 |
8.05 |
|
ISPNRPTSVP |
7.85
|
-9.56 |
6.13 |
|
SEPSAPSCDL |
8.09
|
-5.97 |
9.72 |
| O35716 |
AAPVRPRPCP |
6.19
|
-8.99 |
6.70 |
|
PAPAPGDTHF |
7.77
|
-6.30 |
9.39 |
|
PCPAVPAPAP |
7.95
|
-7.18 |
8.51 |
| Q80U87 |
APPSTPPTHK |
5.90
|
-9.12 |
6.57 |
|
YPPEMAPSSA |
6.80
|
-7.59 |
8.10 |
|
LEEPVPSKLP |
7.98
|
-8.13 |
7.56 |
| Q61234 |
SPPASPLQRQ |
5.34
|
-10.78 |
4.91 |
|
PEPEPAQLNG |
7.23
|
-6.70 |
8.99 |
|
GPEPEPAQLN |
7.58
|
-8.35 |
7.34 |
| Q9JLQ0 |
AAPQVPPKKP |
5.53
|
-9.65 |
6.04 |
|
SPLPSPGNGS |
6.04
|
-8.16 |
7.53 |
|
KKPTAPTKAS |
6.37
|
-9.15 |
6.54 |
| Q60749 |
PPPPVPRGRG |
4.72
|
-10.97 |
4.72 |
|
APPPPPVPRG |
6.00
|
-10.02 |
5.67 |
|
PLPHRPRGGG |
6.86
|
-10.37 |
5.32 |
| Q99JZ7 |
DKPEVPPRVP |
5.81
|
-10.22 |
5.47 |
|
TPPLTPIKSC |
5.82
|
-9.56 |
6.13 |
|
RPPKVPPREP |
6.18
|
-12.05 |
3.64 |
| Q9QUN3 |
GPPSVPRRDY |
4.25
|
-11.60 |
4.09 |
|
HQKPVPLPRF |
6.10
|
-7.22 |
8.47 |
|
KKPATPLKTT |
6.40
|
-9.34 |
6.35 |
| P27870 |
IPPPPGAFGP |
9.79
|
-7.27 |
8.42 |
|
GIPPPPGAFG |
10.11
|
-7.16 |
8.53 |
|
YYGIPPPPGA |
10.17
|
-5.06 |
10.63 |
| P04925 |
NQWNKPSKPK |
10.82
|
-6.01 |
9.68 |
| Q9WU78 |
PPPVLPANRV |
3.98
|
-11.74 |
3.95 |
|
SAPSIPPPAY |
6.14
|
-8.16 |
7.53 |
|
AAPPTPAPRT |
6.17
|
-8.92 |
6.77 |
| Q60992 |
PPTGRPPSRE |
6.87
|
-8.91 |
6.78 |
|
RPPTGRPPSR |
8.91
|
-6.40 |
9.29 |
|
NPAPPGKPVL |
9.43
|
-5.23 |
10.46 |
| P98083 |
PPPPCPGREL |
5.99
|
-11.21 |
4.48 |
|
MLPPPPCPGR |
6.99
|
-9.21 |
6.48 |
|
GPKGEPGKAA |
7.55
|
-7.45 |
8.24 |
| Q9EQ32 |
RPPRVPPRAA |
4.73
|
-12.80 |
2.89 |
|
GPPPPPDNEP |
6.75
|
-10.75 |
4.94 |
|
NRPPVPVPRP |
6.76
|
-10.25 |
5.44 |
| Q61824 |
PAPIRPAPKH |
4.40
|
-9.57 |
6.12 |
|
TAPHCPANVY |
4.78
|
-8.25 |
7.44 |
|
KDPGIPGQSI |
6.67
|
-8.62 |
7.07 |
| Q91ZZ2 |
SPPALPPKKR |
4.09
|
-11.99 |
3.70 |
|
PKPPLPGIRV |
4.97
|
-11.64 |
4.05 |
|
PPPALPPKQR |
4.98
|
-11.99 |
3.70 |
| Q9QYY0 |
TPPRRPVPVA |
5.45
|
-10.78 |
4.91 |
|
SSPKTPPRRP |
6.35
|
-11.44 |
4.25 |
|
MNPNSPPRQH |
6.63
|
-11.20 |
4.49 |
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