Publications

G. Fernandez-Ballester, J. Castresana, J.L.R. Arrondo, J.A. Ferragut and J.M. González Ros. Protein stability and interaction of the Nicotinic Acetylcholine Receptor with cholinergic ligands studied by Fourier-transform Infrared Spectroscopic. Biochemical Journal, 288, 421-426 (1992). MedLine

J. Castresana, G. Fernández-Ballester, A.M. Fernández, J.L. Laynez, J.L.R. Arrondo, J.A. Ferragut and J.M. González Ros. Protein Structural Effects of Agonist Binding to the Nicotinic Acetylcholine Receptor. FEBS Lett., 314, 171-175 (1992). MedLine

J.M. González Ros, A.M. Fernández, G. Fernández-Ballester, J.A. Ferragut J. Castresana and J.L.R. Arrondo. Interaction of the Nicotinic Acetylcholine Receptor with Ligands and Membrane Lipids Studied by Fourier-Transform Infrared Spectroscopy and Photoaffinity Labeling. In: Membrane Proteins: Structures, Interactions and Models. (A. Pullman, B. Pullman and J. Jortner, Eds.). Kluger Academic Publishers, Dordrech (Holland), pp 213-227 (1992). 

A.M. Fernández, G. Fernández-Ballester, J.A. Ferragut and J.M. González Ros. Labeling of the Nicotinic Acetylcholine Receptor by a Photoactivatable Steroid Probe: Effects of Cholesterol and Cholinergic Ligands. Biochim. Biophys. Acta, 1149, 135-144 (1993). MedLine

G. Fernández-Ballester, J. Castresana, A.M. Fernández, J.L.R. Arrondo, J.A. Ferragut and J.M. González Ros. A role for cholesterol as a structural effector of the nicotinic acetylcholine receptor. Biochemistry, 33, 4065-4071 (1994). MedLine

G. Fernández-Ballester, J. Castresana, A.M. Fernández, J.L. Rodríguez Arrondo, J.A. Ferragut and J.M. González Ros. Role of cholesterol as a structural and functional effector of the nicotinic acetylcholine receptor. Biochem. Soc. Trans. 22, 776-780, (1994). MedLine

G. Fernández-Ballester, F. Gavilanes, J.P. Albar, M. Criado, J.A. Ferragut and J.M. González Ros. Adoption of b structure by the inactivating "ball" peptide of the Shaker B potassium channel. Biophys. J. 68, 858-865, (1995). MedLine

M. Gasset, J.M. Mancheño, J. Lacadena, G. Fernández-Ballester, A. Martínez del Pozo, M. Oñaderra and J.G. Gavilanes. Thermal unfolding of the cytotoxin a-sarcin: phospholipid binding induces destabilization of the protein structure. Biochim. Biophys. Acta, 1252, 126-134 (1995). MedLine

G. Fernandez-Ballester, A. Cerdá and V. Martínez. Role of calcium in short-term responses of bean plants to osmotic or saline shocks. J. Plant Physiol., 151, 741-747 (1997). 

G. Fernandez-Ballester, V. Martínez, D. Ruiz, and A. Cerdá. Changes in inorganic and organic solutes in citrus growing under saline stresses. J. Plant Nutrition, 21, 2497-2514 (1998). 

M. Carvajal, F. Del Amor, G. Fernandez-Ballester, V. Martínez and A. Cerdá. Time course of solute accumulation and water relations in muskmelon plants exposed to salt during different growth stages. Plant Science, 138, 103-112 (1998). 

C. Blanes-Mira, C. Ibañez, G. Fernández-Ballester, R. Planells-Cases, E. Pérez-Payá and A. Ferrer-Montiel. Thermal stabilization of the catalytic domain of botulinum neurotoxin E by phosphorylation of a single tyrosine residue. Biochemistry 40, 2234-2242 (2001). MedLine

J. Reina, E. Lacroix, S. D. Hobson, G. Fernandez-Ballester, V. Rybin, M. S. Schwab, L. Serrano and C. Gonzalez. Computer-aided design of a PDZ domain to recognise new target sequences. Nat.Struc.Biol. 9, 621-627 (2002). MedLine

C. Blanes-Mira, J. Clemente, G. Jodas, A. Gil, G. Fernández-Ballester, E. Pérez-Payá, B. Ponsati, L.M. Gutierrez, J.M. García-Anton and A. Ferrer-Montiel. A synthetic hexapeptide (Argireline) with antiwrinkle activity. Inter. J. Cosmetic Science. 24, 303-310 (2002). MedLine

G. Fernandez-Ballester, F. Garcia-Sanchez, A. Cerdá and V. Martínez. Tolerance of citrus rootstocks seedlings to saline stress based on their ability to regulate ion uptake and transport. Tree Physiology. 23. 265-271 (2003). MedLine

G. Fernández-Ballester, J. Maya, A. Martín, S. Parche, J. Gómez, F. Titgemeyer and J. L. Neira. The histidine-phosphocarrier protein of Streptomyces coelicolor folds by a partially folded species at low pH. European Journal of Bichem. 270. 2254-2267-14 (2003). MedLine

J. Villanueva, G. Fernández-Ballester, E. Querol, F. X. Avilés and L. Serrano. Ligand screening by exoproteolysis and mass spectrometry in combination with compuetr modelling. J. Mol. Biol. 330. 1039-1048 (2003). MedLine

C. Blanes-Mira, M.T. Pastor, E. Valera, G. Fernández-Ballester, J. Merino, E. Pérez-Payá and A. Ferrer-Montiel. Identificaction of the SNARE complex modulators that inhibit exocytosis from an a-helix-constrained combinatorial library. Biochem. J. 375, 159-166 (2003). MedLine

C. Blanes-Mira, J.M. Merino, E. Valera, G. Fernández-Ballester, L.M. Gutiérrez, S. Viniegra, E. Pérez-Payá and A. Ferrer-Montiel. Small peptides patterned after the n-terminus domain of snap25 Inhibit snare complex assembly and regulated exocytosis. J.Neurochemistry. 88, 124-135 (2004). MedLine

G. Fernández-Ballester, C. Blanes-Mira and L. Serrano. The Triptophan Switch: Changing Ligand-binding Specificity from Type I to Type II in SH3 Domains. J. Mol. Biol. 335, 619-629 (2004). MedLine

A. Ferrer-Montiel, C. García-Martínez, C. Morenilla-Palao, N. García-Sanz, A. Fernandez, G. Fernandez-Ballester and R. Planells-Cases. Molecular architecture of the vanilloid receptor: insights for drug design. European J. Biochemistry. 271, 1820-1826 (2004). MedLine

N. García-Sanz, A. Fernández-Carvajal, C. Morenilla-Palao, R. Planells-Cases, E. Fajardo, G. Fernández-Ballester and A. Ferrer-Montiel. Identification of a tetramerization domain in the C Terminus of the vanilloid receptor. J Neuroscience. 24, 5307-5314. (2004). MedLine

A.M. van der Sloot, M.M. Mullally, G. Fernandez-Ballester, L. Serrano and W.J. Quax. Stabilization of TRAIL, an all b-sheet multimeric protein, using computational redesign. PEDS. 17:673-680 (2004). MedLine

C. Ibañez, C. Blanes-Mira, G. Fernández-Ballester, R. Planells-Cases, and A. Ferrer-Montiel. Modulation of botulinum neurotoxin A catalytic domain stability by tyrosine phosphorylation. FEBS Letters. 578, 121-127. (2004). MedLine

M.L. Molina, J.A. Encinar, F.N. Barrera, G. Fernandez-Ballester and J.M. Gonzalez-Ros. Influence of C-terminal protein domains and protein-lipid interactions on tetramerization and stability of the potassium channel Kcsa. Biochemistry 43, 14924-14931 (2004). MedLine

M. Caprini M. Fava, P. Valente, G. Fernandez-Ballester, C. Rapisarda, S. Ferroni and A. Ferrer-Montiel. Molecular compatibility of the channel gate and the N-terminus of S5 segment for voltage-gated channel activity. J. Biol. Chem., 280: 18253-18264 (2005). MedLine

F. García-Sánchez, P. Botia, G. Fernández-Ballester, A. Cerdá and V. Martínez López. Uptake, Transport, and Concentration of Chloride and Sodium in Three Citrus Rootstock Seedlings. J. of Plant Nutrition, 28: 1933-1945, (2005). 

Ö. Kempkens, E. Médina, G. Fernandez-Ballester, S. Özüyaman, A. Le Bivic, L. Serrano and E. Knust. Computer modelling in combination with in vitro studies reveals similar binding affinities of Drosophila crumbs for the PDZ domains of stardust and DmPar-6. European Journal Cell Biology. 85:753-767 (2006). MedLine

V. Musi, B. Birdsall, G. Fernandez-Ballester, R. Guerrini, S. Salvatori, L. Serrano and A. Pastore. New approaches to high-throughput structure characterization of SH3 complexes: The example of Myosin-3 and Myosin-5 SH3 domains from S. cerevisiae. Protein Science. 15: 795-807 (2006). MedLine

G. Fernandez-Ballester and L. Serrano. Prediction of Protein-Protein Interaction Based on Structure. Protein Design: Methods and Applications. Methods in Molecular Biology series (R. Guerois and M. López de la Paz, Eds.). THE HUMANA PRESS INC. Totowa, NJ USA (2006) Volume 340, pps. 207-234. MedLine

E Hurtado-Gómez, G. Fernández-Ballester, H. Nothaft, J. Gómez, F. Titgemeyer and J.L. Neira. Biophysical characterization of the Enzyme I of the Streptomyces coelicolor phosphoenolpyruvate: sugar phosphotransferase system. Biophysical Journal 90:4592-604 (2006). MedLine

V. Kölsch, T. Seher, G. Fernandez-Ballester, L. Serrano and M. Leptin. Control of Drosophila gastrulation by apical localisation of adherens junctions and RhoGEF2. Science. 315:384-386 (2007). MedLine

J.A. Poveda, G. Fernández-Ballester, M. Prieto and J.L. Neira. Dynamics of tryptophan in the Histidine-Containing Phosphocarrier protein of Streptomyces coelicolor: evidence of multistate equilibrium unfolding. Biochemistry 46:7252-7260 (2007). MedLine

N. Garcia Sanz, P. Valente, A. Gomis, A. Fernandez-Carvajal, G. Fernandez-Ballester, F. Viana, C. Belmonte and A. Ferrer-Montiel. A role of the Transient Receptor Potential domain of vanilloid receptor I in channel gating. J. Neuroscience 27:11641-11650 (2007). MedLine

J. Lima, T. Feijoo, I. Pereira-Castro, G. Fernández-Ballester, V. Maximo, A. Herrero, L. Serrano, M. Sobrinho-Simoes and G. Garcia-Rostan. High frequency of germline Succinate Dehydrogenase mutations in sporadic cervical paragangliomas in Northern Spain: Mitochondrial succinate dehydrogenase structure-function relationships and clinical-pathological correlations. J. Clinical Endocrinology & Metabolism 92:4853–4864 (2007).  MedLine

P. Valente, N. Garcia Sanz, A. omis Garcia, A. Fernandez-Carvajal, G. Fernandez-Ballester, F. Viana, C. Belmonte and A. Ferrer-Montiel. Identification of molecular determinants of channel gating in the transient receptor potential box of vanilloid receptor I. FASEB J. 22:1-12 (2008). MedLine

M.L. Molina, F.N. Barrera, J.A. Encinar, M.L. Renart, A.M. Fernandez-Carvajal, J.A. Poveda, J. Santoro, M. Bruix, F. Gavilanes, G. Fernandez-Ballester, J.L. Neira, and J.M. Gonzalez-Ros. N-type Inactivation of the Potassium Channel KcsA by the Shaker B “Ball” Peptide. J. Biol. Chem. (2008) 283:18076-18085. MedLine

G. Fernandez-Ballester and A. Ferrer-Montiel. Molecular modelling of the full length human TRPV1 channel in a closed and desensitized states. J Membr. Biol. (2008) (accepted). MedLine

G.M. Garcia-Rostan, A.M. Costa, G. Fernandez-Ballester, M.F. Fresno and J. Cameselle-Teijeiro. Impaired BRAF activity mutant, Gly474Arg, in anaplastic thyroid carcinomas. The Journal of Clinical Endocrinology and Metabolism (2008). HREF

C.W. Liew, G. Glassmeier, M. Vockel, J.M. Brandner, G. Fernandez-Ballester, J.R. Schwarz, S. Schulz, J.M., F. Buck, L. Serrano, D. Richter and H.J. Kreienkamp. Interaction with the multiple PDZ domain protein MUPP1 targets the human somatostatin receptor 3 to epithelial tight junctions. FEBS Letters. (2009) 583:49-54. MedLine

G. Fernandez-Ballester, P. Beltrao, J.M. Gonzalez, Y.H. Song, M. Wilmanns, A. Valencia and L. Serrano. Structure-based prediction of the S. cerevisiae SH3-ligand interactions. Journal Molecular Biology (2009) 388:902-916. MedLine