ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1GBQ2.PDB
Scoring matrix: 1GBQ2_mat
Uniprot code: Q60631
Genome source: Mus musculus
Wild-type ligand: VPPPVPPRRR
Foldx wt ligand score: 1.0
Foldx random average score for Mus musculus: 11.351

Available information for Q60631 in MINT (Nov 2008):
Nš of interacting proteins: 32
 Proteins belonging to other specie: 6
Nš of interactions described: 55
 Interactions with other species: 12

Genome scanning information:
Subcellular location: True
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 13502
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 30944
 Total fragments: 13390911
Proteins after random average filtering: 30939
 Total fragments: 6815718
Proteins after disorder filtering: 22489
 Total fragments: 733289
Proteins after pattern filtering: 16051
 Total fragments: 231350
Proteins after MINT filtering: 13
 Total fragments: 399


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

VPPPVPPRRR

1.00

-13.85

0.00

Best peptides

RRPTMPRRRR

0.00

-10.77

3.08

         
Interactors      
Q62245

VPPPVPPRRR

1.00

-15.15

-1.30

PPPVPPRRRP

2.75

-12.17

1.68

SPPAIPPRQP

2.87

-12.72

1.13

P04925

QWNKPSKPKT

9.11

-4.09

9.76

NQWNKPSKPK

10.29

-5.81

8.04

Q923U0

LPPLPSSHPV

6.43

-9.33

4.52

LSPIVPVPTP

6.85

-7.17

6.68

EAGQISPNRP

7.37

-7.12

6.73

Q02384

IPPPLPPRKK

2.27

-13.40

0.45

PAPPVPPRQN

2.90

-11.98

1.87

DPPAIPPRQP

2.91

-11.87

1.98

Q91ZZ2

SPPALPPKKR

3.77

-10.88

2.97

PPPALPPKQR

4.27

-10.58

3.27

KPPLPGIRVV

4.55

-9.83

4.02

Q60992

RPPTGRPPSR

7.57

-7.78

6.07

GNPAPPGKPV

8.29

-8.23

5.62

PPTGRPPSRE

8.67

-4.91

8.94

O35716

AAPVRPRPCP

5.94

-8.17

5.68

SSPAAPVRPR

5.97

-9.76

4.09

PCPAVPAPAP

6.14

-7.82

6.03

Q80U87

YPPEMAPSSA

5.17

-7.51

6.34

APPSTPPTHK

6.47

-8.80

5.05

PPSTPPTHKV

6.59

-8.41

5.44

Q9EQ32

RPPRVPPRAA

2.56

-12.29

1.56

NRPPVPVPRP

4.61

-10.14

3.71

GPPPPPDNEP

5.11

-10.53

3.32

Q9Z1S8

PRPPKPSQAE

4.79

-10.72

3.13

PPPRPPKPSQ

5.78

-9.07

4.78

QPGSPSPHRK

6.59

-7.82

6.03

P27870

IPPPPGAFGP

5.61

-9.96

3.89

PPPPGAFGPF

8.59

-5.32

8.53

YGIPPPPGAF

9.40

-5.97

7.88

Q62077

DCWDGPDGMP

10.26

-4.04

9.81

CWDGPDGMPV

11.09

-5.31

8.54

Q9QYY0

SSPKTPPRRP

4.59

-9.57

4.28

PRPPKPHPTH

4.76

-10.85

3.00

MNPNSPPRQH

4.92

-9.96

3.89

 


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