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Matrix information:
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ADAN-name: 1GBQ2.PDB
Scoring matrix: 1GBQ2_mat
Uniprot code: Q60631
Genome source: Mus musculus
Wild-type ligand: VPPPVPPRRR
Foldx wt ligand score: 1.0
Foldx random average score for Mus musculus: 11.351 Available information for Q60631 in MINT (Nov 2008):
Nš of interacting proteins: 32
Proteins belonging to other specie: 6
Nš of interactions described: 55
Interactions with other species: 12
Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
Total fragments: 20375566
Proteins after random average filtering: 44441
Total fragments: 10404366
Proteins after disorder filtering: 32223
Total fragments: 1133448
Proteins after pattern filtering: 23097
Total fragments: 359958
Proteins after MINT filtering: 25
Total fragments: 869
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
VPPPVPPRRR |
1.00
|
-13.85 |
0.00 |
| Best peptides |
RRPTMPRRRR |
0.00
|
-10.77 |
3.08 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q62245 |
VPPPVPPRRR |
1.00
|
-15.15 |
-1.30 |
|
PPPVPPRRRP |
2.75
|
-12.17 |
1.68 |
|
SPPAIPPRQP |
2.87
|
-12.72 |
1.13 |
| Q02384 |
IPPPLPPRKK |
2.27
|
-13.40 |
0.45 |
|
PAPPVPPRQN |
2.90
|
-11.98 |
1.87 |
|
DPPAIPPRQP |
2.91
|
-11.87 |
1.98 |
| P39054 |
IPPGVPSRRA |
1.76
|
-11.78 |
2.07 |
|
AAPSRPTIIR |
4.22
|
-10.53 |
3.32 |
|
APPQIPSRPA |
4.36
|
-11.60 |
2.25 |
| P35991 |
KKPLPPEPTA |
7.36
|
-8.35 |
5.50 |
|
KKPLPPTPEE |
7.50
|
-7.73 |
6.12 |
|
PLPPTPEEDQ |
10.70
|
-4.87 |
8.98 |
| Q9Z1S8 |
PRPPKPSQAE |
4.79
|
-10.72 |
3.13 |
|
PPPRPPKPSQ |
5.78
|
-9.07 |
4.78 |
|
QPGSPSPHRK |
6.59
|
-7.82 |
6.03 |
| Q62077 |
DCWDGPDGMP |
10.26
|
-4.04 |
9.81 |
|
CWDGPDGMPV |
11.09
|
-5.31 |
8.54 |
| P70424 |
CPPCAPTCKD |
5.78
|
-8.06 |
5.79 |
|
EGPPPPIRPA |
6.04
|
-10.25 |
3.60 |
|
PPPIRPAGAT |
6.13
|
-8.74 |
5.11 |
| Q8R550 |
LPPRRPERPV |
5.05
|
-11.60 |
2.25 |
|
RPGALPPRRP |
5.50
|
-9.45 |
4.40 |
|
LPPKPGTMAA |
5.52
|
-8.79 |
5.06 |
| Q923U0 |
LPPLPSSHPV |
6.43
|
-9.33 |
4.52 |
|
LSPIVPVPTP |
6.85
|
-7.17 |
6.68 |
|
EAGQISPNRP |
7.37
|
-7.12 |
6.73 |
| O35716 |
AAPVRPRPCP |
5.94
|
-8.17 |
5.68 |
|
SSPAAPVRPR |
5.97
|
-9.76 |
4.09 |
|
PCPAVPAPAP |
6.14
|
-7.82 |
6.03 |
| Q80U87 |
YPPEMAPSSA |
5.17
|
-7.51 |
6.34 |
|
APPSTPPTHK |
6.47
|
-8.80 |
5.05 |
|
PPSTPPTHKV |
6.59
|
-8.41 |
5.44 |
| Q61234 |
SPPASPLQRQ |
4.89
|
-8.82 |
5.03 |
|
SSPGPQPRNL |
6.34
|
-6.94 |
6.91 |
|
DSPPASPLQR |
7.44
|
-7.58 |
6.27 |
| Q9JLQ0 |
AAPQVPPKKP |
4.70
|
-9.79 |
4.06 |
|
VPPPPPAAKI |
5.50
|
-9.88 |
3.97 |
|
KKPTAPTKAS |
6.53
|
-9.02 |
4.83 |
| Q60749 |
PPPPVPRGRG |
4.67
|
-10.48 |
3.37 |
|
APPPPPVPRG |
5.19
|
-10.78 |
3.07 |
|
VPPPPTVRGA |
5.56
|
-11.55 |
2.30 |
| Q99JZ7 |
PPPPQSHRRL |
2.54
|
-10.86 |
2.99 |
|
RPPKVPPREP |
2.83
|
-11.58 |
2.27 |
|
DKPEVPPRVP |
3.89
|
-12.32 |
1.53 |
| Q9QUN3 |
GPPSVPRRDY |
2.47
|
-11.92 |
1.93 |
|
PPTQKPVHQK |
5.96
|
-7.66 |
6.19 |
|
KKPATPLKTT |
6.53
|
-9.38 |
4.47 |
| P27870 |
IPPPPGAFGP |
5.61
|
-9.96 |
3.89 |
|
PPPPGAFGPF |
8.59
|
-5.32 |
8.53 |
|
YGIPPPPGAF |
9.40
|
-5.97 |
7.88 |
| P04925 |
QWNKPSKPKT |
9.11
|
-4.09 |
9.76 |
|
NQWNKPSKPK |
10.29
|
-5.81 |
8.04 |
| Q9WU78 |
NMPYPPVYHQ |
3.46
|
-10.46 |
3.39 |
|
APPTPAPRTM |
3.62
|
-9.59 |
4.26 |
|
PPPVLPANRV |
3.65
|
-10.29 |
3.56 |
| Q60992 |
RPPTGRPPSR |
7.57
|
-7.78 |
6.07 |
|
GNPAPPGKPV |
8.29
|
-8.23 |
5.62 |
|
PPTGRPPSRE |
8.67
|
-4.91 |
8.94 |
| P98083 |
PPPPCPGREL |
3.32
|
-11.18 |
2.67 |
|
GPPNPSLNGS |
5.31
|
-8.06 |
5.79 |
|
RRRKPCSRPL |
6.09
|
-9.71 |
4.14 |
| Q9EQ32 |
RPPRVPPRAA |
2.56
|
-12.29 |
1.56 |
|
NRPPVPVPRP |
4.61
|
-10.14 |
3.71 |
|
GPPPPPDNEP |
5.11
|
-10.53 |
3.32 |
| Q61824 |
PAPIRPAPKH |
5.15
|
-8.61 |
5.24 |
|
RAPSGPARPL |
5.44
|
-9.42 |
4.43 |
|
SPPQKPLPAD |
5.79
|
-8.11 |
5.74 |
| Q91ZZ2 |
SPPALPPKKR |
3.77
|
-10.88 |
2.97 |
|
PPPALPPKQR |
4.27
|
-10.58 |
3.27 |
|
KPPLPGIRVV |
4.55
|
-9.83 |
4.02 |
| Q9QYY0 |
SSPKTPPRRP |
4.59
|
-9.57 |
4.28 |
|
PRPPKPHPTH |
4.76
|
-10.85 |
3.00 |
|
MNPNSPPRQH |
4.92
|
-9.96 |
3.89 |
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