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Matrix information:
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ADAN-name: SHO1_2VKN-9.PDB
Scoring matrix: SHO1_2VKN-9_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 18.47
Foldx random average score for Saccharomyces cerevisiae: 13.023 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 962174
Proteins after disorder filtering: 3135
Total fragments: 42007
Proteins after pattern filtering: 1491
Total fragments: 8377
Proteins after MINT filtering: 22
Total fragments: 292 ROC parameters:
TPR= 0.393
FPR= 0.293
ACC= 0.704
SPC= 0.707
MCC= 0.023 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
18.47
|
-2.59 |
0.00 |
| Best peptides |
RNWREPRW |
0.00
|
-7.88 |
-5.29 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNSK |
10.83
|
-7.76 |
-5.17 |
| Q06604 |
KPLLPTRP |
6.69
|
-10.84 |
-8.25 |
|
LPTRPNKA |
7.16
|
-10.32 |
-7.73 |
|
PPPLPTRR |
9.02
|
-10.84 |
-8.25 |
| P24583 |
LPPQPRKH |
8.29
|
-10.28 |
-7.69 |
|
PLPPQPRK |
9.48
|
-6.96 |
-4.37 |
|
NAPLPPQP |
11.06
|
-6.40 |
-3.81 |
| Q06412 |
RRPPPPPP |
8.40
|
-8.64 |
-6.05 |
|
RPPPPPPL |
8.70
|
-9.13 |
-6.54 |
|
NSPKSPRD |
9.20
|
-7.09 |
-4.50 |
| P40036 |
LPTTPGIR |
9.64
|
-9.37 |
-6.78 |
|
LPPLSPKS |
10.75
|
-7.68 |
-5.09 |
|
PTTPGIRS |
12.76
|
-5.62 |
-3.03 |
| P09620 |
LSNPISKP |
10.75
|
-8.32 |
-5.73 |
|
DPSNIPQM |
11.11
|
-6.06 |
-3.47 |
|
PISKPSIH |
11.15
|
-8.22 |
-5.63 |
| P13186 |
RPPIPAAL |
7.75
|
-8.78 |
-6.19 |
|
LPEREPPT |
7.76
|
-8.95 |
-6.36 |
|
PSYVPNRV |
9.00
|
-8.95 |
-6.36 |
| P39083 |
LLQSPATP |
11.71
|
-6.50 |
-3.91 |
| P38753 |
TPVMPPQR |
10.07
|
-8.08 |
-5.49 |
|
ANNTPVMP |
10.44
|
-8.01 |
-5.42 |
|
NLPIQHPT |
11.03
|
-5.89 |
-3.30 |
| Q08229 |
NPTIPPRS |
5.54
|
-10.32 |
-7.73 |
|
YNPTIPPR |
10.32
|
-7.91 |
-5.32 |
|
NDYNPTIP |
10.93
|
-7.72 |
-5.13 |
| Q00246 |
NLPRLPTP |
10.12
|
-7.75 |
-5.16 |
|
LPRLPTPF |
10.49
|
-7.79 |
-5.20 |
|
EKNLPRLP |
10.95
|
-7.19 |
-4.60 |
| P32448 |
RVPTDSPQ |
11.68
|
-7.35 |
-4.76 |
|
SPQLPSKD |
12.06
|
-7.52 |
-4.93 |
|
PTDSPQLP |
12.39
|
-6.94 |
-4.35 |
| Q04439 |
SKPKEPMF |
9.05
|
-7.18 |
-4.59 |
|
KPKEPMFE |
9.20
|
-7.44 |
-4.85 |
|
NIPTPPQN |
9.36
|
-7.26 |
-4.67 |
| P35197 |
TPAKPPQE |
9.20
|
-8.75 |
-6.16 |
|
FGSTPAKP |
10.59
|
-8.64 |
-6.05 |
|
RPDHLPPS |
10.80
|
-7.60 |
-5.01 |
| Q12446 |
RNNRPVPP |
7.16
|
-8.43 |
-5.84 |
|
APPPPPRR |
7.94
|
-10.08 |
-7.49 |
|
APPPPPRA |
7.99
|
-9.23 |
-6.64 |
| P08018 |
RAPRRPLS |
7.55
|
-6.80 |
-4.21 |
|
HPTRPNVA |
10.02
|
-8.31 |
-5.72 |
|
RPNVAPHK |
10.54
|
-7.17 |
-4.58 |
| P39969 |
FKLLPPQP |
8.59
|
-8.80 |
-6.21 |
|
PIPSPTRN |
9.52
|
-7.57 |
-4.98 |
|
RAPKPPSY |
9.53
|
-7.73 |
-5.14 |
| Q03790 |
ATPSPFRP |
9.35
|
-8.60 |
-6.01 |
|
LNGFPSAP |
10.96
|
-6.46 |
-3.87 |
|
FPSAPQPL |
11.55
|
-7.73 |
-5.14 |
| P41809 |
YPTTPYPS |
11.26
|
-8.07 |
-5.48 |
|
YTSSPSVP |
12.13
|
-6.69 |
-4.10 |
|
LSTYPTTP |
12.36
|
-5.87 |
-3.28 |
| Q05080 |
LRQKPDKP |
8.04
|
-10.71 |
-8.12 |
|
QKPDKPRP |
9.83
|
-8.39 |
-5.80 |
|
KPDKPRPI |
10.02
|
-9.65 |
-7.06 |
| P53297 |
MFYHPSMP |
8.99
|
-8.35 |
-5.76 |
|
MPFQPQPM |
9.34
|
-8.81 |
-6.22 |
|
HPSMPQMM |
9.69
|
-10.27 |
-7.68 |
| P22147 |
FPPPPPMT |
8.23
|
-10.33 |
-7.74 |
|
HPLHPHQM |
9.09
|
-8.31 |
-5.72 |
|
NIPTPPHP |
9.89
|
-7.11 |
-4.52 |
|
