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Matrix information:
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ADAN-name: SHO1_2VKN-8.PDB
Scoring matrix: SHO1_2VKN-8_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.57
Foldx random average score for Saccharomyces cerevisiae: 12.335 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 1295448
Proteins after disorder filtering: 3340
Total fragments: 97306
Proteins after pattern filtering: 1629
Total fragments: 14693
Proteins after MINT filtering: 24
Total fragments: 478 ROC parameters:
TPR= 0.429
FPR= 0.32
ACC= 0.678
SPC= 0.68
MCC= 0.024 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
14.57
|
-2.72 |
0.00 |
| Best peptides |
HWPFRPEM |
0.00
|
-7.19 |
-4.47 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPN |
8.08
|
-7.25 |
-4.53 |
|
LPLTPNSK |
10.11
|
-4.88 |
-2.16 |
| Q06604 |
EKPLLPTR |
5.42
|
-9.77 |
-7.05 |
|
SPPPLPTR |
5.83
|
-9.91 |
-7.19 |
|
KGPRMPSR |
6.95
|
-7.89 |
-5.17 |
| P24583 |
APLPPQPR |
8.23
|
-5.19 |
-2.47 |
|
ANAPLPPQ |
8.58
|
-7.05 |
-4.33 |
|
NAPLPPQP |
9.31
|
-6.48 |
-3.76 |
| Q06412 |
RRPPPPPP |
5.27
|
-8.57 |
-5.85 |
|
ERRPPPPP |
5.54
|
-7.81 |
-5.09 |
|
FFTKPPPP |
6.34
|
-7.71 |
-4.99 |
| P40036 |
KSLPTTPG |
10.27
|
-4.08 |
-1.36 |
|
SKSLPTTP |
10.30
|
-4.81 |
-2.09 |
|
LPPLSPKS |
10.46
|
-6.05 |
-3.33 |
| P09620 |
NPISKPSI |
7.52
|
-8.11 |
-5.39 |
|
DPSNIPQM |
8.34
|
-6.78 |
-4.06 |
|
PSNIPQMH |
9.94
|
-1.67 |
1.05 |
| P13186 |
NNIPLTPL |
7.63
|
-6.57 |
-3.85 |
|
SYVPNRVP |
8.05
|
-5.86 |
-3.14 |
|
PEREPPTY |
8.28
|
-6.48 |
-3.76 |
| P32334 |
DFSSPSSP |
9.59
|
-4.38 |
-1.66 |
|
SSPSSPTT |
11.08
|
-4.34 |
-1.62 |
|
SPSSPTTT |
11.79
|
-2.72 |
-0.00 |
| P39083 |
QSPATPSN |
9.10
|
-5.58 |
-2.86 |
|
LQSPATPS |
10.50
|
-3.36 |
-0.64 |
|
SPATPSNV |
11.99
|
-2.71 |
0.01 |
| P38753 |
TPVMPPQR |
7.30
|
-7.14 |
-4.42 |
|
ISPPVPGP |
8.27
|
-7.17 |
-4.45 |
|
NTPVMPPQ |
8.55
|
-7.21 |
-4.49 |
| Q08229 |
DYNPTIPP |
5.01
|
-7.44 |
-4.72 |
|
YNPTIPPR |
7.04
|
-8.25 |
-5.53 |
|
TRPLPSTP |
8.44
|
-5.03 |
-2.31 |
| Q00246 |
PRLPTPFA |
7.06
|
-7.33 |
-4.61 |
|
LPRLPTPF |
7.20
|
-5.37 |
-2.65 |
|
SSNLPESP |
9.07
|
-4.21 |
-1.49 |
| P32448 |
DSPQLPSK |
6.61
|
-8.45 |
-5.73 |
|
PRVPTDSP |
6.65
|
-7.44 |
-4.72 |
|
PQLPSKDK |
9.24
|
-4.30 |
-1.58 |
| Q04439 |
SSKPKEPM |
6.02
|
-5.70 |
-2.98 |
|
SKPKEPMF |
6.70
|
-6.82 |
-4.10 |
|
PAPPPPGM |
6.96
|
-7.90 |
-5.18 |
| P35197 |
STPAKPPQ |
7.69
|
-6.76 |
-4.04 |
|
RPDHLPPS |
8.82
|
-7.68 |
-4.96 |
|
PAKPPQER |
9.03
|
-3.84 |
-1.12 |
| Q12446 |
PFPFPVPQ |
5.10
|
-7.78 |
-5.06 |
|
PVPPPPPM |
5.85
|
-7.94 |
-5.22 |
|
PFPFPIPE |
5.90
|
-5.30 |
-2.58 |
| P08018 |
QHPTRPNV |
6.36
|
-8.40 |
-5.68 |
|
PRLPSDKF |
6.82
|
-5.11 |
-2.39 |
|
PRRPLSTQ |
7.14
|
-6.75 |
-4.03 |
| P39969 |
AQPPKSPL |
6.03
|
-6.77 |
-4.05 |
|
RRAPKPPS |
6.71
|
-7.47 |
-4.75 |
|
VSPRRAPK |
6.91
|
-7.20 |
-4.48 |
| Q03790 |
GFPSAPQP |
7.56
|
-8.07 |
-5.35 |
|
PSAPQPLF |
9.07
|
-5.50 |
-2.78 |
|
KPTATPSP |
9.39
|
-7.16 |
-4.44 |
| P41809 |
TYPTTPYP |
5.70
|
-8.35 |
-5.63 |
|
PYPSPNSY |
6.56
|
-6.54 |
-3.82 |
|
STYPTTPY |
9.18
|
-5.42 |
-2.70 |
| Q05080 |
QKPDKPRP |
6.30
|
-9.94 |
-7.22 |
|
LRQKPDKP |
7.13
|
-4.17 |
-1.45 |
|
RQKPDKPR |
7.94
|
-5.57 |
-2.85 |
| P25344 |
PGPSPNEA |
10.89
|
-2.55 |
0.17 |
|
NTPGPSPN |
11.28
|
-3.06 |
-0.34 |
|
ANTPGPSP |
11.29
|
-4.22 |
-1.50 |
| P53297 |
GYPGGIPF |
5.57
|
-7.52 |
-4.80 |
|
PFQPQPMF |
5.63
|
-7.38 |
-4.66 |
|
YHPSMPQM |
6.57
|
-9.17 |
-6.45 |
| P22147 |
SFPPPPPM |
3.54
|
-9.31 |
-6.59 |
|
PYNIPPGF |
3.95
|
-7.90 |
-5.18 |
|
LNIPTPPH |
8.12
|
-5.56 |
-2.84 |
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