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Matrix information:
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ADAN-name: SHO1_2VKN-7.PDB
Scoring matrix: SHO1_2VKN-7_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 15.48
Foldx random average score for Saccharomyces cerevisiae: 12.644 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 961633
Proteins after disorder filtering: 3137
Total fragments: 55087
Proteins after pattern filtering: 1569
Total fragments: 10248
Proteins after MINT filtering: 24
Total fragments: 368 ROC parameters:
TPR= 0.429
FPR= 0.308
ACC= 0.689
SPC= 0.692
MCC= 0.027 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AGAAAAAA |
15.48
|
-3.84 |
0.00 |
| Best peptides |
FRKRPERR |
0.00
|
-9.41 |
-5.57 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLTPNSKY |
9.11
|
-7.02 |
-3.18 |
|
KPLPLTPN |
9.92
|
-6.19 |
-2.35 |
| Q06604 |
PPSPPAKR |
7.88
|
-9.73 |
-5.89 |
|
GPRMPSRG |
8.04
|
-8.41 |
-4.57 |
|
PAPPVSRS |
8.26
|
-7.36 |
-3.52 |
| P24583 |
PLPPQPRK |
7.13
|
-8.82 |
-4.98 |
|
LPPQPRKH |
9.86
|
-7.35 |
-3.51 |
|
RANAPLPP |
11.56
|
-6.15 |
-2.31 |
| Q06412 |
RRPPPPPP |
7.19
|
-8.89 |
-5.05 |
|
FTKPPPPL |
7.21
|
-7.98 |
-4.14 |
|
RPPPPPPL |
7.71
|
-9.18 |
-5.34 |
| P40036 |
ELPPLSPK |
9.80
|
-6.32 |
-2.48 |
|
PLSPKSTV |
11.95
|
-4.38 |
-0.54 |
|
PTTPGIRS |
12.13
|
-6.06 |
-2.22 |
| P09620 |
PISKPSIH |
9.19
|
-6.94 |
-3.10 |
|
LSNPISKP |
11.02
|
-6.69 |
-2.85 |
|
DPSNIPQM |
11.17
|
-4.85 |
-1.01 |
| P13186 |
LPEREPPT |
10.07
|
-6.37 |
-2.53 |
|
QQQAPLMP |
10.35
|
-7.40 |
-3.56 |
|
APSYVPNR |
10.63
|
-5.58 |
-1.74 |
| P32334 |
FSSPSSPT |
11.02
|
-4.87 |
-1.03 |
|
SPSSPTTT |
12.37
|
-3.79 |
0.05 |
| P39083 |
SPATPSNV |
11.83
|
-4.22 |
-0.38 |
|
QSPATPSN |
12.53
|
-3.62 |
0.22 |
| P38753 |
TPVMPPQR |
8.36
|
-7.43 |
-3.59 |
|
YPSNLPIQ |
8.48
|
-6.65 |
-2.81 |
|
PVMPPQRQ |
10.14
|
-9.03 |
-5.19 |
| Q08229 |
NPTIPPRS |
9.62
|
-8.96 |
-5.12 |
|
YNPTIPPR |
9.69
|
-6.81 |
-2.97 |
|
RPLPSTPN |
10.97
|
-4.60 |
-0.76 |
| Q00246 |
NLPRLPTP |
9.81
|
-7.27 |
-3.43 |
|
PRLPTPFA |
9.97
|
-5.61 |
-1.77 |
|
SNLPESPG |
11.75
|
-3.71 |
0.13 |
| P32448 |
RVPTDSPQ |
9.90
|
-5.04 |
-1.20 |
|
SPQLPSKD |
10.34
|
-6.33 |
-2.49 |
|
TDSPQLPS |
12.26
|
-3.73 |
0.11 |
| Q04439 |
SKPKEPMF |
7.81
|
-5.93 |
-2.09 |
|
RPSPPTAA |
8.86
|
-6.48 |
-2.64 |
|
KPAPPPPG |
9.27
|
-7.67 |
-3.83 |
| P35197 |
TPAKPPQE |
8.53
|
-7.13 |
-3.29 |
|
FGSTPAKP |
8.63
|
-7.09 |
-3.25 |
|
RPDHLPPS |
8.85
|
-6.90 |
-3.06 |
| Q12446 |
APPPPPRR |
6.48
|
-9.94 |
-6.10 |
|
VPPPPPMR |
6.55
|
-9.20 |
-5.36 |
|
APPPPPRA |
7.06
|
-9.70 |
-5.86 |
| P08018 |
RAPRRPLS |
7.07
|
-7.66 |
-3.82 |
|
STQHPTRP |
8.69
|
-8.08 |
-4.24 |
|
PRLPSDKF |
8.90
|
-5.80 |
-1.96 |
| P39969 |
RRAPKPPS |
8.21
|
-5.32 |
-1.48 |
|
RAPKPPSY |
8.44
|
-7.13 |
-3.29 |
|
PIPSPTRN |
8.70
|
-7.40 |
-3.56 |
| Q03790 |
PSAPQPLF |
10.37
|
-5.78 |
-1.94 |
|
FPSAPQPL |
10.48
|
-6.31 |
-2.47 |
|
ATPSPFRP |
10.61
|
-7.22 |
-3.38 |
| P41809 |
TTPYPSPN |
9.83
|
-5.53 |
-1.69 |
|
YTSSPSVP |
10.40
|
-5.64 |
-1.80 |
|
PSAPVAIS |
11.06
|
-5.79 |
-1.95 |
| Q05080 |
LRQKPDKP |
8.29
|
-7.16 |
-3.32 |
|
QKPDKPRP |
9.46
|
-5.70 |
-1.86 |
|
KPDKPRPI |
9.61
|
-7.44 |
-3.60 |
| P25344 |
NTPGPSPN |
12.00
|
-3.80 |
0.04 |
|
TPGPSPNE |
12.64
|
-2.66 |
1.18 |
| P53297 |
PPKPISKT |
7.96
|
-9.27 |
-5.43 |
|
YMPFQPQP |
8.31
|
-8.44 |
-4.60 |
|
PEGKPPQK |
9.51
|
-7.70 |
-3.86 |
| P22147 |
FPPPPPMT |
5.68
|
-10.80 |
-6.96 |
|
FGQPISFP |
8.95
|
-7.51 |
-3.67 |
|
IPKGEPFD |
10.23
|
-5.32 |
-1.48 |
|
