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Matrix information:
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ADAN-name: SHO1_2VKN-6.PDB
Scoring matrix: SHO1_2VKN-6_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 20.72
Foldx random average score for Saccharomyces cerevisiae: 17.638 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2171323
Proteins after random average filtering: 5078
Total fragments: 927288
Proteins after disorder filtering: 3067
Total fragments: 55173
Proteins after pattern filtering: 1583
Total fragments: 12629
Proteins after MINT filtering: 24
Total fragments: 427 ROC parameters:
TPR= 0.429
FPR= 0.31
ACC= 0.687
SPC= 0.69
MCC= 0.027 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
20.72
|
-1.90 |
0.00 |
| Best peptides |
RRRRPPRPRR |
0.00
|
-10.03 |
-8.13 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLTPNSKYNG |
12.80
|
-4.23 |
-2.33 |
|
SKPLPLTPNS |
14.50
|
-5.76 |
-3.86 |
|
LPLTPNSKYN |
15.00
|
-6.47 |
-4.57 |
| Q06604 |
KPLLPTRPNK |
8.40
|
-10.18 |
-8.28 |
|
LPTRPNKAEV |
8.92
|
-8.50 |
-6.60 |
|
GPRMPSRGRP |
9.61
|
-11.80 |
-9.90 |
| P24583 |
LPPQPRKHDK |
11.91
|
-8.79 |
-6.89 |
|
NAPLPPQPRK |
13.68
|
-9.68 |
-7.78 |
|
PLPPQPRKHD |
14.02
|
-7.32 |
-5.42 |
| Q06412 |
KERRPPPPPP |
9.91
|
-8.39 |
-6.49 |
|
RRPPPPPPLL |
10.87
|
-8.49 |
-6.59 |
|
FFTKPPPPLS |
11.49
|
-8.81 |
-6.91 |
| P40036 |
KIELPPLSPK |
12.05
|
-7.63 |
-5.73 |
|
LPTTPGIRSG |
13.46
|
-7.86 |
-5.96 |
|
SKSLPTTPGI |
14.54
|
-6.53 |
-4.63 |
| P09620 |
TKLSNPISKP |
14.72
|
-4.01 |
-2.11 |
|
KLSNPISKPS |
15.07
|
-5.52 |
-3.62 |
|
SEVPDPSNIP |
15.84
|
-3.10 |
-1.20 |
| P13186 |
QEPLPEREPP |
10.72
|
-10.42 |
-8.52 |
|
RPPIPAALPP |
11.69
|
-8.60 |
-6.70 |
|
QNNIPLTPLA |
13.83
|
-6.12 |
-4.22 |
| P32334 |
SPSSPTTTDI |
17.33
|
-3.67 |
-1.77 |
|
DFSSPSSPTT |
17.47
|
-3.86 |
-1.96 |
| P39083 |
SPATPSNVSM |
15.54
|
-5.11 |
-3.21 |
|
LLQSPATPSN |
15.89
|
-5.33 |
-3.43 |
| P38753 |
PVMPPQRQSY |
12.47
|
-9.29 |
-7.39 |
|
TPVMPPQRQS |
13.46
|
-7.14 |
-5.24 |
|
ANNTPVMPPQ |
14.14
|
-6.47 |
-4.57 |
| Q08229 |
NPTIPPRSKD |
8.01
|
-10.56 |
-8.66 |
|
YLTRPLPSTP |
11.00
|
-7.13 |
-5.23 |
|
NDYNPTIPPR |
12.60
|
-6.88 |
-4.98 |
| Q00246 |
EKNLPRLPTP |
12.99
|
-7.67 |
-5.77 |
|
NLPRLPTPFA |
13.53
|
-6.22 |
-4.32 |
|
LDEKNLPRLP |
13.73
|
-3.63 |
-1.73 |
| P32448 |
SPQLPSKDKS |
11.25
|
-6.54 |
-4.64 |
|
RVPTDSPQLP |
15.73
|
-3.77 |
-1.87 |
|
PTDSPQLPSK |
17.47
|
-3.79 |
-1.89 |
| Q04439 |
RPSPPTAATR |
10.82
|
-7.40 |
-5.50 |
|
HSKKPAPPPP |
12.66
|
-6.04 |
-4.14 |
|
SNARPSPPTA |
12.89
|
-5.49 |
-3.59 |
| P35197 |
NQSRPDHLPP |
10.41
|
-7.52 |
-5.62 |
|
FGSTPAKPPQ |
12.24
|
-6.82 |
-4.92 |
|
TPAKPPQERS |
13.13
|
-7.89 |
-5.99 |
| Q12446 |
APPPPPRASR |
8.32
|
-11.76 |
-9.86 |
|
LPQLPNRNNR |
8.50
|
-11.25 |
-9.35 |
|
RPVPPPPPMR |
8.83
|
-9.54 |
-7.64 |
| P08018 |
HPTRPNVAPH |
9.00
|
-8.45 |
-6.55 |
|
RAPRRPLSTQ |
10.25
|
-5.55 |
-3.65 |
|
VDGPPPRLPS |
10.28
|
-8.89 |
-6.99 |
| P39969 |
SPRRAPKPPS |
8.99
|
-7.35 |
-5.45 |
|
FKLLPPQPGS |
11.31
|
-8.02 |
-6.12 |
|
SPAQPPKSPL |
11.96
|
-6.38 |
-4.48 |
| Q03790 |
FDGKPTATPS |
12.89
|
-6.72 |
-4.82 |
|
FPSAPQPLFM |
15.00
|
-6.51 |
-4.61 |
|
LNGFPSAPQP |
15.34
|
-5.30 |
-3.40 |
| P41809 |
YPTTPYPSPN |
13.76
|
-6.16 |
-4.26 |
|
SPSVPVAVSS |
14.70
|
-6.50 |
-4.60 |
|
LSTYPTTPYP |
15.90
|
-4.76 |
-2.86 |
| Q05080 |
LRQKPDKPRP |
9.30
|
-10.60 |
-8.70 |
|
RQKPDKPRPI |
12.78
|
-4.23 |
-2.33 |
|
KPDKPRPIVG |
12.82
|
-7.41 |
-5.51 |
| P25344 |
TANTPGPSPN |
17.07
|
-4.64 |
-2.74 |
| P53297 |
HPSMPQMMPV |
11.06
|
-8.71 |
-6.81 |
|
NSSLPPKPIS |
11.89
|
-6.10 |
-4.20 |
|
MFYHPSMPQM |
12.57
|
-9.36 |
-7.46 |
| P22147 |
FPPPPPMTNV |
11.40
|
-11.57 |
-9.67 |
|
HPHQMPYPNM |
11.48
|
-7.39 |
-5.49 |
|
HPLHPHQMPY |
12.77
|
-7.68 |
-5.78 |
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