|
Matrix information:
(Help)
ADAN-name: SHO1_2VKN-30.PDB
Scoring matrix: SHO1_2VKN-30_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 22.92
Foldx random average score for Saccharomyces cerevisiae: 16.791 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5078
Total fragments: 1029459
Proteins after disorder filtering: 3073
Total fragments: 49592
Proteins after pattern filtering: 1562
Total fragments: 11285
Proteins after MINT filtering: 24
Total fragments: 386 ROC parameters:
TPR= 0.429
FPR= 0.306
ACC= 0.691
SPC= 0.694
MCC= 0.028 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
22.92
|
-3.26 |
0.00 |
| Best peptides |
RDLRENRPF |
0.00
|
-10.23 |
-6.97 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPNS |
12.03
|
-9.53 |
-6.27 |
|
LPLTPNSKY |
12.64
|
-5.02 |
-1.76 |
|
PLTPNSKYN |
15.66
|
-7.84 |
-4.58 |
| Q06604 |
KPLLPTRPN |
8.61
|
-7.75 |
-4.49 |
|
PPLPTRRDH |
9.06
|
-9.05 |
-5.79 |
|
SFEKGPRMP |
10.05
|
-7.00 |
-3.74 |
| P24583 |
PLPPQPRKH |
12.12
|
-9.09 |
-5.83 |
|
RANAPLPPQ |
12.50
|
-9.49 |
-6.23 |
|
APLPPQPRK |
12.66
|
-9.92 |
-6.66 |
| Q06412 |
RRPPPPPPL |
10.20
|
-11.71 |
-8.45 |
|
KERRPPPPP |
11.12
|
-9.46 |
-6.20 |
|
RPPPPPPLL |
11.20
|
-11.41 |
-8.15 |
| P40036 |
KIELPPLSP |
11.36
|
-8.57 |
-5.31 |
|
KSLPTTPGI |
11.85
|
-8.92 |
-5.66 |
|
IELPPLSPK |
12.72
|
-8.95 |
-5.69 |
| P09620 |
LSNPISKPS |
13.39
|
-7.46 |
-4.20 |
|
VPDPSNIPQ |
14.40
|
-8.20 |
-4.94 |
|
SNPISKPSI |
15.20
|
-7.46 |
-4.20 |
| P13186 |
LPEREPPTY |
10.45
|
-9.04 |
-5.78 |
|
PSYVPNRVP |
10.77
|
-7.46 |
-4.20 |
|
QEPLPEREP |
11.48
|
-8.80 |
-5.54 |
| P32334 |
FSSPSSPTT |
16.04
|
-6.93 |
-3.67 |
| P39083 |
HLLQSPATP |
13.59
|
-6.23 |
-2.97 |
|
PATPSNVSM |
13.92
|
-8.25 |
-4.99 |
| P38753 |
SNLPIQHPT |
11.25
|
-8.64 |
-5.38 |
|
SPYPSNLPI |
11.32
|
-8.11 |
-4.85 |
|
TPVMPPQRQ |
13.26
|
-7.40 |
-4.14 |
| Q08229 |
RPLPSTPNE |
10.04
|
-10.55 |
-7.29 |
|
NPTIPPRSK |
11.96
|
-7.70 |
-4.44 |
|
DYNPTIPPR |
15.40
|
-8.15 |
-4.89 |
| Q00246 |
KNLPRLPTP |
8.91
|
-10.63 |
-7.37 |
|
SNLPESPGT |
12.48
|
-7.88 |
-4.62 |
|
EKNLPRLPT |
14.44
|
-7.68 |
-4.42 |
| P32448 |
TDSPQLPSK |
13.60
|
-8.14 |
-4.88 |
|
SPQLPSKDK |
14.45
|
-4.96 |
-1.70 |
|
PQLPSKDKS |
14.55
|
-6.65 |
-3.39 |
| Q04439 |
ANIPPPPPP |
11.66
|
-9.63 |
-6.37 |
|
PTPPQNRDV |
11.96
|
-8.24 |
-4.98 |
|
KPAPPPPGM |
12.51
|
-10.77 |
-7.51 |
| P35197 |
NQSRPDHLP |
11.99
|
-7.13 |
-3.87 |
|
RPDHLPPSQ |
13.67
|
-8.98 |
-5.72 |
|
TPAKPPQER |
14.20
|
-6.91 |
-3.65 |
| Q12446 |
RPLPQLPNR |
7.75
|
-11.25 |
-7.99 |
|
RPVPPPPPM |
8.59
|
-11.79 |
-8.53 |
|
VRLPAPPPP |
9.97
|
-8.62 |
-5.36 |
| P08018 |
RAPRRPLST |
10.23
|
-9.96 |
-6.70 |
|
PRLPSDKFS |
10.35
|
-8.99 |
-5.73 |
|
VDGPPPRLP |
11.26
|
-7.65 |
-4.39 |
| P39969 |
FKLLPPQPG |
10.88
|
-7.73 |
-4.47 |
|
RRAPKPPSY |
10.95
|
-10.11 |
-6.85 |
|
KLLPPQPGS |
11.21
|
-10.69 |
-7.43 |
| Q03790 |
TATPSPFRP |
11.88
|
-6.49 |
-3.23 |
|
PSAPQPLFM |
14.25
|
-8.22 |
-4.96 |
|
KPTATPSPF |
15.61
|
-7.06 |
-3.80 |
| P41809 |
TPYPSPNSY |
14.12
|
-7.05 |
-3.79 |
|
TYPTTPYPS |
14.76
|
-5.52 |
-2.26 |
|
STYPTTPYP |
15.25
|
-7.19 |
-3.93 |
| Q05080 |
LRQKPDKPR |
10.20
|
-8.77 |
-5.51 |
|
RQKPDKPRP |
11.64
|
-10.95 |
-7.69 |
|
QKPDKPRPI |
12.36
|
-6.32 |
-3.06 |
| P25344 |
TANTPGPSP |
16.73
|
-4.39 |
-1.13 |
| P53297 |
SSLPPKPIS |
11.12
|
-8.94 |
-5.68 |
|
YMPFQPQPM |
13.14
|
-7.76 |
-4.50 |
|
PFQPQPMFY |
13.41
|
-8.11 |
-4.85 |
| P22147 |
VGLPYNIPP |
9.99
|
-8.61 |
-5.35 |
|
NGLHPLHPH |
11.29
|
-7.77 |
-4.51 |
|
LNIPTPPHP |
11.52
|
-9.72 |
-6.46 |
|
