|
Matrix information:
(Help)
ADAN-name: SHO1_2VKN-29.PDB
Scoring matrix: SHO1_2VKN-29_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.26
Foldx random average score for Saccharomyces cerevisiae: 17.500 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2171323
Proteins after random average filtering: 5078
Total fragments: 879323
Proteins after disorder filtering: 2972
Total fragments: 44234
Proteins after pattern filtering: 1512
Total fragments: 10687
Proteins after MINT filtering: 24
Total fragments: 340 ROC parameters:
TPR= 0.429
FPR= 0.296
ACC= 0.701
SPC= 0.704
MCC= 0.03 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
22.26
|
-3.28 |
0.00 |
| Best peptides |
HWDFRPPRWR |
0.00
|
-10.50 |
-7.22 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLPLTPNSKY |
14.24
|
-8.22 |
-4.94 |
|
LPLTPNSKYN |
15.42
|
-5.74 |
-2.46 |
|
KPLPLTPNSK |
16.76
|
-6.08 |
-2.80 |
| Q06604 |
LLPTRPNKAE |
9.46
|
-12.02 |
-8.74 |
|
EKPLLPTRPN |
9.55
|
-12.45 |
-9.17 |
|
KGPRMPSRGR |
10.42
|
-9.76 |
-6.48 |
| P24583 |
APLPPQPRKH |
11.06
|
-9.52 |
-6.24 |
|
PLPPQPRKHD |
11.77
|
-9.40 |
-6.12 |
|
ANAPLPPQPR |
12.92
|
-9.48 |
-6.20 |
| Q06412 |
VKERRPPPPP |
10.63
|
-12.51 |
-9.23 |
|
PNSPKSPRDS |
11.39
|
-6.22 |
-2.94 |
|
EFFTKPPPPL |
12.77
|
-8.91 |
-5.63 |
| P40036 |
ELPPLSPKST |
11.74
|
-7.43 |
-4.15 |
|
SLPTTPGIRS |
12.52
|
-9.66 |
-6.38 |
|
KIELPPLSPK |
15.22
|
-7.02 |
-3.74 |
| P09620 |
SNPISKPSIH |
15.55
|
-6.50 |
-3.22 |
|
TKLSNPISKP |
15.60
|
-8.80 |
-5.52 |
|
EVPDPSNIPQ |
15.60
|
-5.22 |
-1.94 |
| P13186 |
QQEPLPEREP |
11.12
|
-11.82 |
-8.54 |
|
PLPEREPPTY |
11.20
|
-9.14 |
-5.86 |
|
APSYVPNRVP |
12.54
|
-8.11 |
-4.83 |
| P32334 |
ADFSSPSSPT |
17.30
|
-5.55 |
-2.27 |
|
DFSSPSSPTT |
17.37
|
-3.39 |
-0.11 |
| P39083 |
HLLQSPATPS |
13.96
|
-8.06 |
-4.78 |
|
DHLLQSPATP |
16.14
|
-5.28 |
-2.00 |
|
QSPATPSNVS |
17.34
|
-6.85 |
-3.57 |
| P38753 |
TPVMPPQRQS |
13.06
|
-9.24 |
-5.96 |
|
NTPVMPPQRQ |
13.65
|
-8.87 |
-5.59 |
|
PYPSNLPIQH |
14.36
|
-9.68 |
-6.40 |
| Q08229 |
YNPTIPPRSK |
8.06
|
-11.55 |
-8.27 |
|
TNDYNPTIPP |
14.00
|
-6.26 |
-2.98 |
|
LTRPLPSTPN |
15.76
|
-7.08 |
-3.80 |
| Q00246 |
KNLPRLPTPF |
10.91
|
-11.11 |
-7.83 |
|
LDEKNLPRLP |
13.31
|
-9.16 |
-5.88 |
|
NLPRLPTPFA |
13.55
|
-7.99 |
-4.71 |
| P32448 |
DSPQLPSKDK |
14.13
|
-7.84 |
-4.56 |
|
PQLPSKDKSQ |
15.93
|
-7.53 |
-4.25 |
|
RVPTDSPQLP |
16.45
|
-4.81 |
-1.53 |
| Q04439 |
NNIPTPPQNR |
12.89
|
-9.48 |
-6.20 |
|
PPPPPSSKPK |
12.96
|
-7.26 |
-3.98 |
|
SKKPAPPPPG |
13.71
|
-8.50 |
-5.22 |
| P35197 |
STPAKPPQER |
12.01
|
-9.69 |
-6.41 |
|
PAKPPQERSA |
12.96
|
-8.79 |
-5.51 |
|
GFGSTPAKPP |
13.82
|
-8.35 |
-5.07 |
| Q12446 |
PPPPRASRPT |
8.27
|
-12.04 |
-8.76 |
|
PAPPPPPRRG |
10.09
|
-11.90 |
-8.62 |
|
PLPQLPNRNN |
10.73
|
-11.68 |
-8.40 |
| P08018 |
IVDGPPPRLP |
10.43
|
-8.29 |
-5.01 |
|
RAPRRPLSTQ |
12.69
|
-8.19 |
-4.91 |
|
GPPPRLPSDK |
12.79
|
-9.63 |
-6.35 |
| P39969 |
VSPRRAPKPP |
9.94
|
-8.39 |
-5.11 |
|
CFKLLPPQPG |
11.73
|
-8.18 |
-4.90 |
|
SPIPSPTRNS |
12.38
|
-8.94 |
-5.66 |
| Q03790 |
GFPSAPQPLF |
14.74
|
-7.55 |
-4.27 |
|
TFDGKPTATP |
15.25
|
-6.91 |
-3.63 |
|
GKPTATPSPF |
15.63
|
-5.70 |
-2.42 |
| P41809 |
ALSTYPTTPY |
14.73
|
-8.98 |
-5.70 |
|
TTPYPSPNSY |
16.11
|
-5.07 |
-1.79 |
|
TYPTTPYPSP |
16.65
|
-7.14 |
-3.86 |
| Q05080 |
RQKPDKPRPI |
12.19
|
-8.65 |
-5.37 |
|
QKPDKPRPIV |
13.91
|
-8.96 |
-5.68 |
|
PDKPRPIVGE |
14.29
|
-7.34 |
-4.06 |
| P25344 |
NTPGPSPNEA |
16.90
|
-4.42 |
-1.14 |
| P53297 |
SNSSLPPKPI |
12.11
|
-8.11 |
-4.83 |
|
SLPPKPISKT |
12.47
|
-10.09 |
-6.81 |
|
PFQPQPMFYH |
12.88
|
-9.48 |
-6.20 |
| P22147 |
LNIPTPPHPM |
11.98
|
-10.47 |
-7.19 |
|
LHPHQMPYPN |
12.39
|
-12.03 |
-8.75 |
|
SFPPPPPMTN |
13.39
|
-9.69 |
-6.41 |
|
