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Matrix information:
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ADAN-name: SHO1_2VKN-28.PDB
Scoring matrix: SHO1_2VKN-28_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.96
Foldx random average score for Saccharomyces cerevisiae: 18.371 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2171323
Proteins after random average filtering: 5078
Total fragments: 1118788
Proteins after disorder filtering: 3110
Total fragments: 56777
Proteins after pattern filtering: 1514
Total fragments: 9189
Proteins after MINT filtering: 24
Total fragments: 320 ROC parameters:
TPR= 0.429
FPR= 0.297
ACC= 0.7
SPC= 0.703
MCC= 0.03 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
19.96
|
-3.27 |
0.00 |
| Best peptides |
RPPRFPRKSR |
0.00
|
-18.49 |
-15.22 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPNSK |
10.96
|
-11.01 |
-7.74 |
|
LPLTPNSKYN |
14.09
|
-10.07 |
-6.80 |
|
SKPLPLTPNS |
17.76
|
-8.66 |
-5.39 |
| Q06604 |
KPLLPTRPNK |
9.12
|
-15.63 |
-12.36 |
|
RVKPAPPVSR |
10.45
|
-9.43 |
-6.16 |
|
PPPLPTRRDH |
10.51
|
-14.49 |
-11.22 |
| P24583 |
LPPQPRKHDK |
10.38
|
-13.11 |
-9.84 |
|
APLPPQPRKH |
14.70
|
-10.47 |
-7.20 |
|
NAPLPPQPRK |
14.74
|
-9.53 |
-6.26 |
| Q06412 |
KPPPPLSTSR |
9.01
|
-12.59 |
-9.32 |
|
NSPKSPRDSS |
11.82
|
-7.48 |
-4.21 |
|
RPPPPPPLLY |
11.93
|
-12.43 |
-9.16 |
| P40036 |
IELPPLSPKS |
14.23
|
-10.72 |
-7.45 |
|
LPTTPGIRSG |
14.32
|
-9.27 |
-6.00 |
|
KSLPTTPGIR |
15.34
|
-7.68 |
-4.41 |
| P09620 |
PDPSNIPQMH |
15.06
|
-7.74 |
-4.47 |
|
DPSNIPQMHA |
15.66
|
-10.58 |
-7.31 |
|
VPDPSNIPQM |
15.83
|
-8.67 |
-5.40 |
| P13186 |
IPAALPPSDM |
12.61
|
-11.15 |
-7.88 |
|
IPMSPNYGNQ |
13.19
|
-10.94 |
-7.67 |
|
FKAPSYVPNR |
14.39
|
-9.26 |
-5.99 |
| P32334 |
SPSSPTTTDI |
17.72
|
-7.88 |
-4.61 |
| P39083 |
SPATPSNVSM |
14.22
|
-9.59 |
-6.32 |
|
LLQSPATPSN |
15.40
|
-7.49 |
-4.22 |
| P38753 |
PVMPPQRQSY |
12.36
|
-11.83 |
-8.56 |
|
LPIQHPTNSA |
13.46
|
-8.65 |
-5.38 |
|
NTPVMPPQRQ |
15.92
|
-8.30 |
-5.03 |
| Q08229 |
NPTIPPRSKD |
11.35
|
-11.55 |
-8.28 |
|
YNPTIPPRSK |
11.82
|
-9.21 |
-5.94 |
|
PTIPPRSKDR |
11.95
|
-9.44 |
-6.17 |
| Q00246 |
NLPRLPTPFA |
12.74
|
-12.64 |
-9.37 |
|
LPESPGTLDE |
13.61
|
-9.94 |
-6.67 |
|
PESPGTLDEK |
17.75
|
-7.61 |
-4.34 |
| P32448 |
DSPQLPSKDK |
14.26
|
-9.71 |
-6.44 |
|
PTDSPQLPSK |
14.67
|
-6.82 |
-3.55 |
|
PQLPSKDKSQ |
17.83
|
-3.88 |
-0.61 |
| Q04439 |
RPSPPTAATR |
9.72
|
-12.27 |
-9.00 |
|
KPAPPPPGMQ |
11.28
|
-11.21 |
-7.94 |
|
PPPPPPPSSK |
11.57
|
-11.22 |
-7.95 |
| P35197 |
RPDHLPPSQG |
13.41
|
-12.42 |
-9.15 |
|
TPAKPPQERS |
14.59
|
-9.91 |
-6.64 |
|
SRPDHLPPSQ |
16.07
|
-4.74 |
-1.47 |
| Q12446 |
APPPPPRASR |
7.19
|
-14.20 |
-10.93 |
|
RPVPPPPPMR |
9.62
|
-13.06 |
-9.79 |
|
IPEIPSTQSA |
10.42
|
-9.58 |
-6.31 |
| P08018 |
RAPRRPLSTQ |
9.57
|
-9.89 |
-6.62 |
|
APRRPLSTQH |
12.42
|
-14.38 |
-11.11 |
|
PPPRLPSDKF |
13.97
|
-13.55 |
-10.28 |
| P39969 |
KPPSYPSPAQ |
11.66
|
-10.80 |
-7.53 |
|
KLLPPQPGSK |
12.00
|
-11.20 |
-7.93 |
|
ALSPIPSPTR |
13.53
|
-9.50 |
-6.23 |
| Q03790 |
FPSAPQPLFM |
13.23
|
-11.40 |
-8.13 |
|
KPTATPSPFR |
15.49
|
-9.12 |
-5.85 |
|
FDGKPTATPS |
17.16
|
-8.88 |
-5.61 |
| P41809 |
YTSSPSAPVA |
14.68
|
-7.63 |
-4.36 |
|
YTSSPSVPVA |
14.95
|
-7.93 |
-4.66 |
|
YTSSPSAPAA |
15.32
|
-8.18 |
-4.91 |
| Q05080 |
KPDKPRPIVG |
12.37
|
-12.22 |
-8.95 |
|
QKPDKPRPIV |
14.83
|
-10.09 |
-6.82 |
|
PDKPRPIVGE |
17.74
|
-6.72 |
-3.45 |
| P25344 |
NTPGPSPNEA |
17.19
|
-6.94 |
-3.67 |
| P53297 |
SSLPPKPISK |
14.08
|
-8.73 |
-5.46 |
|
PEGKPPQKTS |
14.40
|
-8.09 |
-4.82 |
|
YPGGIPFQGM |
14.45
|
-11.55 |
-8.28 |
| P22147 |
IPPPAPHGFG |
13.01
|
-10.06 |
-6.79 |
|
NIPTPPHPMN |
13.41
|
-9.82 |
-6.55 |
|
LPYNIPPGFM |
13.54
|
-11.40 |
-8.13 |
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