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Matrix information:
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ADAN-name: SHO1_2VKN-26.PDB
Scoring matrix: SHO1_2VKN-26_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.4
Foldx random average score for Saccharomyces cerevisiae: 14.644 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5077
Total fragments: 933500
Proteins after disorder filtering: 2991
Total fragments: 47495
Proteins after pattern filtering: 1534
Total fragments: 11427
Proteins after MINT filtering: 21
Total fragments: 408 ROC parameters:
TPR= 0.375
FPR= 0.301
ACC= 0.695
SPC= 0.699
MCC= 0.017 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
17.40
|
-2.10 |
0.00 |
| Best peptides |
DDRPRRFPR |
0.00
|
-13.68 |
-11.58 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLPLTPNSK |
13.72
|
-6.98 |
-4.88 |
|
SKPLPLTPN |
13.95
|
-6.04 |
-3.94 |
|
KPLPLTPNS |
14.09
|
-7.85 |
-5.75 |
| Q06604 |
PPLPTRRDH |
7.26
|
-8.93 |
-6.83 |
|
EEKPLLPTR |
7.50
|
-9.95 |
-7.85 |
|
GPRMPSRGR |
8.12
|
-6.62 |
-4.52 |
| P24583 |
PPQPRKHDK |
8.66
|
-9.11 |
-7.01 |
|
NAPLPPQPR |
9.40
|
-8.73 |
-6.63 |
|
PLPPQPRKH |
9.52
|
-9.11 |
-7.01 |
| P13186 |
EPLPEREPP |
9.50
|
-10.80 |
-8.70 |
|
KAPSYVPNR |
9.56
|
-7.54 |
-5.44 |
|
IPMSPNYGN |
11.22
|
-6.79 |
-4.69 |
| P41809 |
TYPTTPYPS |
11.76
|
-6.80 |
-4.70 |
|
TSSPSVPVA |
13.53
|
-6.90 |
-4.80 |
|
SSPSAPAAI |
13.79
|
-4.34 |
-2.24 |
| Q05080 |
RQKPDKPRP |
9.85
|
-9.06 |
-6.96 |
|
LRQKPDKPR |
9.97
|
-7.56 |
-5.46 |
|
QKPDKPRPI |
10.39
|
-5.39 |
-3.29 |
| Q08229 |
DYNPTIPPR |
7.15
|
-9.58 |
-7.48 |
|
NPTIPPRSK |
11.80
|
-4.96 |
-2.86 |
|
LTRPLPSTP |
12.18
|
-6.53 |
-4.43 |
| P40036 |
IELPPLSPK |
11.95
|
-6.28 |
-4.18 |
|
PTTPGIRSG |
12.29
|
-5.64 |
-3.54 |
|
SLPTTPGIR |
12.58
|
-6.75 |
-4.65 |
| Q00246 |
DEKNLPRLP |
10.54
|
-5.63 |
-3.53 |
|
EKNLPRLPT |
11.58
|
-9.91 |
-7.81 |
|
KNLPRLPTP |
12.02
|
-9.04 |
-6.94 |
| P53297 |
SLPPKPISK |
9.33
|
-9.85 |
-7.75 |
|
MGMYMPFQP |
9.84
|
-7.19 |
-5.09 |
|
PSMPQMMPV |
9.85
|
-8.64 |
-6.54 |
| P22147 |
IPPPAPHGF |
9.80
|
-8.69 |
-6.59 |
|
FPPPPPMTN |
10.28
|
-9.39 |
-7.29 |
|
FGQPISFPP |
10.88
|
-7.53 |
-5.43 |
| P32448 |
TDSPQLPSK |
11.84
|
-7.73 |
-5.63 |
|
PQLPSKDKS |
12.36
|
-6.47 |
-4.37 |
|
SPQLPSKDK |
12.57
|
-6.33 |
-4.23 |
| P35197 |
TPAKPPQER |
8.79
|
-6.71 |
-4.61 |
|
QSRPDHLPP |
11.12
|
-8.91 |
-6.81 |
|
SRPDHLPPS |
12.21
|
-6.90 |
-4.80 |
| Q12446 |
PPPPPRASR |
6.25
|
-11.65 |
-9.55 |
|
PPPPPRRGP |
7.74
|
-9.09 |
-6.99 |
|
PAPPPPPHR |
8.09
|
-9.78 |
-7.68 |
| P08018 |
DGPPPRLPS |
8.72
|
-13.96 |
-11.86 |
|
PTRPNVAPH |
9.92
|
-6.92 |
-4.82 |
|
STQHPTRPN |
10.47
|
-4.49 |
-2.39 |
| P39969 |
LSPIPSPTR |
10.40
|
-6.98 |
-4.88 |
|
PAQPPKSPL |
10.64
|
-6.88 |
-4.78 |
|
PRRAPKPPS |
10.88
|
-6.65 |
-4.55 |
| P09620 |
SNPISKPSI |
10.62
|
-5.90 |
-3.80 |
|
PDPSNIPQM |
11.32
|
-7.78 |
-5.68 |
|
PSNIPQMHA |
13.31
|
-5.20 |
-3.10 |
| Q03790 |
TATPSPFRP |
11.48
|
-7.81 |
-5.71 |
|
PSAPQPLFM |
12.41
|
-7.23 |
-5.13 |
|
PTATPSPFR |
13.08
|
-6.12 |
-4.02 |
| Q04439 |
SSKPKEPMF |
9.71
|
-8.36 |
-6.26 |
|
PSPPTAATR |
10.23
|
-6.97 |
-4.87 |
|
SKKPAPPPP |
10.33
|
-8.82 |
-6.72 |
| Q06412 |
ERRPPPPPP |
8.86
|
-9.45 |
-7.35 |
|
SPNSPKSPR |
10.09
|
-3.96 |
-1.86 |
|
RRPPPPPPL |
10.24
|
-8.83 |
-6.73 |
| P38753 |
PVMPPQRQS |
10.77
|
-7.59 |
-5.49 |
|
NTPVMPPQR |
10.88
|
-9.05 |
-6.95 |
|
SNLPIQHPT |
12.72
|
-7.10 |
-5.00 |
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