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Matrix information:
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ADAN-name: SHO1_2VKN-23.PDB
Scoring matrix: SHO1_2VKN-23_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.18
Foldx random average score for Saccharomyces cerevisiae: 10.865 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2186557
Proteins after random average filtering: 5078
Total fragments: 1299427
Proteins after disorder filtering: 3439
Total fragments: 92470
Proteins after pattern filtering: 1620
Total fragments: 11450
Proteins after MINT filtering: 24
Total fragments: 420 ROC parameters:
TPR= 0.429
FPR= 0.318
ACC= 0.679
SPC= 0.682
MCC= 0.025 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
11.18
|
-1.91 |
0.00 |
| Best peptides |
RKIRRWF |
0.00
|
-3.84 |
-1.93 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTP |
8.40
|
-3.87 |
-1.96 |
|
PLTPNSK |
10.51
|
-4.04 |
-2.13 |
|
LPLTPNS |
10.58
|
-3.91 |
-2.00 |
| Q06604 |
LPTRPNK |
5.86
|
-5.06 |
-3.15 |
|
KGPRMPS |
6.78
|
-5.33 |
-3.42 |
|
RVKPAPP |
6.91
|
-5.94 |
-4.03 |
| P24583 |
LPPQPRK |
5.86
|
-3.08 |
-1.17 |
|
PPQPRKH |
9.02
|
-4.91 |
-3.00 |
|
PLPPQPR |
9.37
|
-5.33 |
-3.42 |
| Q06412 |
RPPPPPP |
6.29
|
-6.93 |
-5.02 |
|
RRPPPPP |
6.36
|
-4.76 |
-2.85 |
|
TKPPPPL |
7.04
|
-2.50 |
-0.59 |
| P40036 |
LPPLSPK |
8.20
|
-2.93 |
-1.02 |
|
KSLPTTP |
9.12
|
-3.51 |
-1.60 |
|
LPTTPGI |
9.60
|
-2.79 |
-0.88 |
| P09620 |
PISKPSI |
7.13
|
-1.95 |
-0.04 |
|
NPISKPS |
8.46
|
-4.19 |
-2.28 |
|
PDPSNIP |
9.24
|
-2.54 |
-0.63 |
| P13186 |
LPEREPP |
5.14
|
-3.87 |
-1.96 |
|
PPIPAAL |
7.47
|
-2.86 |
-0.95 |
|
IPAALPP |
8.50
|
-4.03 |
-2.12 |
| P32334 |
FSSPSSP |
9.09
|
-1.77 |
0.14 |
|
SPSSPTT |
9.81
|
-0.48 |
1.43 |
|
SSPSSPT |
10.56
|
-0.87 |
1.04 |
| P39083 |
LQSPATP |
8.93
|
-1.92 |
-0.01 |
|
QSPATPS |
9.38
|
-2.98 |
-1.07 |
| P38753 |
LPIQHPT |
6.69
|
-5.18 |
-3.27 |
|
TPVMPPQ |
7.74
|
-4.58 |
-2.67 |
|
PVPGPAL |
9.04
|
-3.58 |
-1.67 |
| Q08229 |
RPLPSTP |
7.58
|
-5.04 |
-3.13 |
|
PTIPPRS |
8.23
|
-1.98 |
-0.07 |
|
TPVQPGG |
8.75
|
-3.21 |
-1.30 |
| Q00246 |
KNLPRLP |
7.94
|
-6.40 |
-4.49 |
|
NLPRLPT |
8.00
|
-2.49 |
-0.58 |
|
LPESPGT |
8.07
|
-3.23 |
-1.32 |
| P32448 |
PTDSPQL |
7.78
|
-2.51 |
-0.60 |
|
TDSPQLP |
8.46
|
-3.82 |
-1.91 |
|
RVPTDSP |
9.45
|
-4.52 |
-2.61 |
| Q04439 |
KPKEPMF |
5.38
|
-1.54 |
0.37 |
|
KKPAPPP |
5.82
|
-4.90 |
-2.99 |
|
SKPKEPM |
6.97
|
0.53 |
2.44 |
| P35197 |
TPAKPPQ |
7.29
|
-0.86 |
1.05 |
|
STPAKPP |
8.98
|
-2.37 |
-0.46 |
|
PAKPPQE |
9.76
|
-3.36 |
-1.45 |
| Q12446 |
RLPAPPP |
5.57
|
-5.52 |
-3.61 |
|
RGPAPPP |
5.72
|
-5.08 |
-3.17 |
|
RPVPPPP |
5.87
|
-6.83 |
-4.92 |
| P08018 |
RAPRRPL |
3.38
|
-5.68 |
-3.77 |
|
APRRPLS |
7.29
|
-3.62 |
-1.71 |
|
HPTRPNV |
7.31
|
-6.37 |
-4.46 |
| P39969 |
RAPKPPS |
6.16
|
-2.89 |
-0.98 |
|
SPRRAPK |
6.45
|
-4.02 |
-2.11 |
|
QPPKSPL |
6.49
|
-4.21 |
-2.30 |
| Q03790 |
FPSAPQP |
6.79
|
-4.03 |
-2.12 |
|
TPSPFRP |
7.37
|
-0.97 |
0.94 |
|
KPTATPS |
8.09
|
-3.94 |
-2.03 |
| P41809 |
YPTTPYP |
8.36
|
-3.55 |
-1.64 |
|
SPSAPAA |
8.99
|
-2.61 |
-0.70 |
|
SPSAPVA |
9.26
|
-2.57 |
-0.66 |
| Q05080 |
KPDKPRP |
3.70
|
-4.31 |
-2.40 |
|
RQKPDKP |
6.95
|
-5.08 |
-3.17 |
|
PDKPRPI |
7.45
|
-2.21 |
-0.30 |
| P25344 |
NTPGPSP |
10.17
|
-2.73 |
-0.82 |
|
PGPSPNE |
10.35
|
-1.70 |
0.21 |
|
TPGPSPN |
10.78
|
-3.49 |
-1.58 |
| P53297 |
LPPKPIS |
7.00
|
-1.86 |
0.05 |
|
MPFQPQP |
7.15
|
-2.03 |
-0.12 |
|
HPSMPQM |
7.53
|
-5.02 |
-3.11 |
| P22147 |
IPKGEPF |
6.98
|
-3.05 |
-1.14 |
|
FPPPPPM |
7.15
|
-2.77 |
-0.86 |
|
QPISFPP |
7.30
|
-4.25 |
-2.34 |
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