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Matrix information:
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ADAN-name: SHO1_2VKN-20.PDB
Scoring matrix: SHO1_2VKN-20_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.97
Foldx random average score for Saccharomyces cerevisiae: 16.167 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5078
Total fragments: 992554
Proteins after disorder filtering: 3211
Total fragments: 74017
Proteins after pattern filtering: 1492
Total fragments: 6849
Proteins after MINT filtering: 24
Total fragments: 216 ROC parameters:
TPR= 0.429
FPR= 0.292
ACC= 0.705
SPC= 0.708
MCC= 0.031 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
15.97
|
-2.59 |
0.00 |
| Best peptides |
WPPRFGRHM |
0.00
|
-13.32 |
-10.73 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNSKY |
9.50
|
-7.41 |
-4.83 |
|
PLTPNSKYN |
12.09
|
-4.82 |
-2.24 |
|
KPLPLTPNS |
14.49
|
-4.28 |
-1.70 |
| Q06604 |
PPSPPAKRI |
9.29
|
-9.20 |
-6.61 |
|
LPTRPNKAE |
9.41
|
-9.26 |
-6.67 |
|
GPRMPSRGR |
9.58
|
-9.74 |
-7.16 |
| P24583 |
LPPQPRKHD |
7.66
|
-8.34 |
-5.75 |
|
APLPPQPRK |
10.82
|
-7.60 |
-5.01 |
|
PPQPRKHDK |
13.72
|
-3.45 |
-0.87 |
| Q06412 |
KPPPPLSTS |
9.64
|
-6.10 |
-3.51 |
|
PPPPLSTSR |
9.74
|
-6.45 |
-3.87 |
|
PPPPLLYST |
11.04
|
-5.89 |
-3.30 |
| P40036 |
LPTTPGIRS |
7.82
|
-6.07 |
-3.49 |
|
PPLSPKSTV |
11.54
|
-5.74 |
-3.16 |
|
ELPPLSPKS |
14.03
|
-4.48 |
-1.90 |
| P09620 |
PDPSNIPQM |
12.72
|
-3.28 |
-0.69 |
|
LSNPISKPS |
13.03
|
-4.48 |
-1.90 |
|
PSNIPQMHA |
15.24
|
-3.72 |
-1.14 |
| P13186 |
IPLTPLATN |
11.77
|
-5.28 |
-2.70 |
|
IPMSPNYGN |
11.83
|
-5.59 |
-3.00 |
|
PMSPNYGNQ |
13.47
|
-4.24 |
-1.66 |
| P32334 |
FSSPSSPTT |
13.49
|
-4.41 |
-1.83 |
|
DFSSPSSPT |
15.13
|
-1.92 |
0.67 |
|
SPSSPTTTD |
15.50
|
-3.60 |
-1.02 |
| P39083 |
SPATPSNVS |
14.00
|
-6.71 |
-4.13 |
|
LLQSPATPS |
14.68
|
-3.27 |
-0.69 |
| P38753 |
SPPVPGPAL |
9.17
|
-7.31 |
-4.72 |
|
PVMPPQRQS |
12.32
|
-6.99 |
-4.41 |
|
NLPIQHPTN |
14.55
|
-5.55 |
-2.96 |
| Q08229 |
TPVQPGGHY |
8.09
|
-8.02 |
-5.43 |
|
LPTPVQPGG |
12.11
|
-5.87 |
-3.29 |
|
PVQPGGHYK |
12.24
|
-6.76 |
-4.17 |
| Q00246 |
LPESPGTLD |
13.84
|
-2.65 |
-0.06 |
|
SNLPESPGT |
15.07
|
-3.52 |
-0.94 |
| P32448 |
RVPTDSPQL |
9.40
|
-6.26 |
-3.67 |
|
TDSPQLPSK |
11.65
|
-4.96 |
-2.38 |
|
PRVPTDSPQ |
12.26
|
-4.38 |
-1.79 |
| Q04439 |
APPPPGMQN |
9.38
|
-6.27 |
-3.68 |
|
IPTPPQNRD |
10.66
|
-8.67 |
-6.09 |
|
RPSPPTAAT |
12.79
|
-6.86 |
-4.28 |
| P35197 |
PAKPPQERS |
15.54
|
-4.39 |
-1.80 |
| Q12446 |
RPLPQLPNR |
8.04
|
-6.60 |
-4.01 |
|
PPPPPHRHV |
8.55
|
-11.59 |
-9.00 |
|
LPDPPQHNS |
10.09
|
-6.92 |
-4.34 |
| P08018 |
APRRPLSTQ |
9.94
|
-7.93 |
-5.34 |
|
GPPPRLPSD |
10.65
|
-5.28 |
-2.70 |
|
PRRPLSTQH |
11.77
|
-4.33 |
-1.75 |
| P39969 |
LPPQPGSKK |
6.23
|
-8.23 |
-5.65 |
|
LSPIPSPTR |
12.09
|
-5.47 |
-2.88 |
|
APKPPSYPS |
12.11
|
-6.28 |
-3.70 |
| Q03790 |
PTATPSPFR |
11.51
|
-4.45 |
-1.87 |
|
FPSAPQPLF |
15.83
|
-5.50 |
-2.92 |
| P41809 |
YTSSPSAPV |
13.39
|
-4.76 |
-2.17 |
|
YTSSPSVPV |
13.75
|
-3.64 |
-1.06 |
|
YTSSPSAPA |
13.85
|
-3.50 |
-0.92 |
| Q05080 |
LRQKPDKPR |
8.96
|
-7.29 |
-4.71 |
|
KPDKPRPIV |
14.62
|
-6.79 |
-4.21 |
|
RQKPDKPRP |
15.99
|
-7.29 |
-4.71 |
| P25344 |
NTPGPSPNE |
14.08
|
-3.10 |
-0.52 |
| P53297 |
LPPKPISKT |
9.99
|
-7.03 |
-4.45 |
|
MPFQPQPMF |
10.17
|
-8.18 |
-5.59 |
|
SPHVPAGFM |
11.72
|
-7.80 |
-5.21 |
| P22147 |
PPAPHGFGQ |
10.41
|
-5.58 |
-3.00 |
|
PPPPPMTNV |
11.36
|
-6.77 |
-4.18 |
|
IPTPPHPMN |
12.29
|
-6.43 |
-3.84 |
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