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Matrix information:
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ADAN-name: SHO1_2VKN-16.PDB
Scoring matrix: SHO1_2VKN-16_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 19.53
Foldx random average score for Saccharomyces cerevisiae: 20.154 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5078
Total fragments: 1047131
Proteins after disorder filtering: 3245
Total fragments: 85306
Proteins after pattern filtering: 1581
Total fragments: 9979
Proteins after MINT filtering: 24
Total fragments: 315 ROC parameters:
TPR= 0.429
FPR= 0.31
ACC= 0.687
SPC= 0.69
MCC= 0.027 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
19.53
|
2.78 |
0.00 |
| Best peptides |
RHPLWSRKG |
0.00
|
-2.65 |
-5.43 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNSKY |
12.42
|
-4.10 |
-6.88 |
|
SKPLPLTPN |
16.93
|
-2.60 |
-5.38 |
|
PLPLTPNSK |
17.19
|
-2.28 |
-5.06 |
| Q06604 |
KPLLPTRPN |
10.09
|
-7.09 |
-9.87 |
|
PPPLPTRRD |
10.92
|
-7.77 |
-10.55 |
|
GPRMPSRGR |
12.44
|
-7.74 |
-10.52 |
| P24583 |
PLPPQPRKH |
13.81
|
-2.54 |
-5.32 |
|
LPPQPRKHD |
15.58
|
-4.95 |
-7.73 |
| Q06412 |
NSPKSPRDS |
15.18
|
-0.36 |
-3.14 |
|
PMVSPSSQS |
16.82
|
-0.85 |
-3.63 |
|
KPPPPLSTS |
17.01
|
-3.28 |
-6.06 |
| P40036 |
LPTTPGIRS |
13.83
|
-3.59 |
-6.37 |
|
SKSLPTTPG |
14.73
|
-2.31 |
-5.09 |
|
PTTPGIRSG |
16.95
|
-0.46 |
-3.24 |
| P09620 |
NPISKPSIH |
17.00
|
-0.24 |
-3.02 |
|
PSNIPQMHA |
17.37
|
-0.48 |
-3.26 |
|
KLSNPISKP |
17.98
|
-3.47 |
-6.25 |
| P13186 |
QEPLPEREP |
12.46
|
-4.71 |
-7.49 |
|
LPEREPPTY |
13.17
|
-6.05 |
-8.83 |
|
RPPIPAALP |
14.52
|
-4.84 |
-7.62 |
| P32334 |
SPSSPTTTD |
18.78
|
-0.98 |
-3.76 |
|
ADFSSPSSP |
19.23
|
-1.61 |
-4.39 |
| P39083 |
SPATPSNVS |
15.15
|
-1.17 |
-3.95 |
|
HLLQSPATP |
18.86
|
-0.93 |
-3.71 |
|
LLQSPATPS |
19.21
|
0.05 |
-2.73 |
| P38753 |
YPSNLPIQH |
14.57
|
-2.42 |
-5.20 |
|
AHISPPVPG |
15.25
|
-0.29 |
-3.07 |
|
NLPIQHPTN |
15.38
|
-1.94 |
-4.72 |
| Q08229 |
NPTIPPRSK |
11.79
|
-5.30 |
-8.08 |
|
TPVQPGGHY |
13.97
|
-0.73 |
-3.51 |
|
TRPLPSTPN |
14.76
|
-3.11 |
-5.89 |
| Q00246 |
LPRLPTPFA |
12.91
|
-3.30 |
-6.08 |
|
NLPRLPTPF |
14.52
|
-1.82 |
-4.60 |
|
DEKNLPRLP |
15.16
|
-2.73 |
-5.51 |
| P32448 |
SPQLPSKDK |
17.40
|
-3.46 |
-6.24 |
|
DSPQLPSKD |
19.33
|
-0.30 |
-3.08 |
|
VPTDSPQLP |
19.44
|
-1.93 |
-4.71 |
| Q04439 |
RHSKKPAPP |
15.52
|
-2.56 |
-5.34 |
|
KKPAPPPPG |
15.90
|
-3.54 |
-6.32 |
|
KPKEPMFEA |
16.38
|
-0.12 |
-2.90 |
| P35197 |
PDHLPPSQG |
12.73
|
-5.00 |
-7.78 |
|
RPDHLPPSQ |
17.07
|
-3.32 |
-6.10 |
|
NQSRPDHLP |
17.54
|
-2.53 |
-5.31 |
| Q12446 |
LPQLPNRNN |
9.06
|
-6.96 |
-9.74 |
|
APPPPPRRG |
10.08
|
-6.98 |
-9.76 |
|
LPPLPNQFA |
12.40
|
-4.17 |
-6.95 |
| P08018 |
PPRLPSDKF |
11.79
|
-4.37 |
-7.15 |
|
QHPTRPNVA |
13.09
|
-0.35 |
-3.13 |
|
VDGPPPRLP |
16.34
|
-3.60 |
-6.38 |
| P39969 |
FKLLPPQPG |
12.15
|
-4.98 |
-7.76 |
|
PPQPGSKKG |
14.31
|
-2.13 |
-4.91 |
|
RAPKPPSYP |
14.49
|
-4.30 |
-7.08 |
| Q03790 |
FPSAPQPLF |
13.48
|
-2.80 |
-5.58 |
|
KPTATPSPF |
15.71
|
-2.36 |
-5.14 |
|
FDGKPTATP |
16.51
|
-6.12 |
-8.90 |
| P41809 |
YPTTPYPSP |
15.72
|
-3.47 |
-6.25 |
|
TPYPSPNSY |
15.91
|
-2.50 |
-5.28 |
|
LSTYPTTPY |
17.92
|
-0.04 |
-2.82 |
| Q05080 |
RQKPDKPRP |
17.91
|
-2.80 |
-5.58 |
|
PDKPRPIVG |
18.46
|
0.85 |
-1.93 |
|
KPDKPRPIV |
18.77
|
0.04 |
-2.74 |
| P25344 |
TANTPGPSP |
18.21
|
-1.34 |
-4.12 |
|
TPGPSPNEA |
18.97
|
0.66 |
-2.12 |
| P53297 |
MPQMMPVMG |
12.10
|
-4.35 |
-7.13 |
|
MPFQPQPMF |
12.68
|
-3.00 |
-5.78 |
|
YPGGIPFQG |
14.58
|
-2.12 |
-4.90 |
| P22147 |
LHPLHPHQM |
13.35
|
-3.96 |
-6.74 |
|
LPYNIPPGF |
14.46
|
-4.31 |
-7.09 |
|
PPPAPHGFG |
14.86
|
-2.30 |
-5.08 |
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