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Matrix information:
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ADAN-name: SHO1_2VKN-15.PDB
Scoring matrix: SHO1_2VKN-15_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 20.63
Foldx random average score for Saccharomyces cerevisiae: 16.305 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5078
Total fragments: 849148
Proteins after disorder filtering: 2797
Total fragments: 31026
Proteins after pattern filtering: 1168
Total fragments: 3823
Proteins after MINT filtering: 21
Total fragments: 125 ROC parameters:
TPR= 0.375
FPR= 0.228
ACC= 0.767
SPC= 0.772
MCC= 0.036 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
20.63
|
-1.02 |
0.00 |
| Best peptides |
RRRRIRRMK |
0.00
|
-10.14 |
-9.12 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNSKY |
15.46
|
-6.89 |
-5.87 |
|
PLPLTPNSK |
15.74
|
-5.96 |
-4.94 |
| Q06604 |
PLLPTRPNK |
11.11
|
-9.48 |
-8.46 |
|
PPLPTRRDH |
12.20
|
-8.08 |
-7.05 |
|
NIPSSKPAG |
12.51
|
-4.09 |
-3.06 |
| P24583 |
PPQPRKHDK |
11.22
|
-7.96 |
-6.94 |
|
LPPQPRKHD |
12.60
|
-8.24 |
-7.21 |
|
APLPPQPRK |
14.97
|
-6.60 |
-5.57 |
| P13186 |
LPEREPPTY |
13.24
|
-6.90 |
-5.88 |
|
RPPIPAALP |
13.89
|
-6.99 |
-5.96 |
|
APSYVPNRV |
15.62
|
-4.36 |
-3.34 |
| P22147 |
HPLHPHQMP |
12.86
|
-6.97 |
-5.95 |
|
IPTPPHPMN |
14.17
|
-6.59 |
-5.56 |
|
LHPLHPHQM |
15.21
|
-5.65 |
-4.63 |
| Q05080 |
KPDKPRPIV |
8.70
|
-9.02 |
-7.99 |
|
RQKPDKPRP |
10.80
|
-5.99 |
-4.96 |
| P38753 |
NLPIQHPTN |
12.59
|
-6.24 |
-5.21 |
|
NTPVMPPQR |
16.05
|
-5.90 |
-4.88 |
| Q08229 |
NPTIPPRSK |
11.59
|
-7.04 |
-6.02 |
|
RPLPSTPNE |
14.99
|
-4.57 |
-3.55 |
|
LPSTPNEDS |
16.24
|
-5.97 |
-4.95 |
| P40036 |
PPLSPKSTV |
12.12
|
-5.12 |
-4.10 |
|
IELPPLSPK |
15.82
|
-5.83 |
-4.80 |
|
LPPLSPKST |
15.95
|
-5.29 |
-4.27 |
| Q00246 |
NLPRLPTPF |
14.14
|
-5.27 |
-4.24 |
|
EKNLPRLPT |
15.94
|
-7.30 |
-6.28 |
|
LPRLPTPFA |
15.94
|
-5.84 |
-4.81 |
| P53297 |
YHPSMPQMM |
12.81
|
-5.45 |
-4.43 |
|
MPQMMPVMG |
14.00
|
-8.00 |
-6.97 |
|
LPPKPISKT |
14.29
|
-5.69 |
-4.67 |
| Q04439 |
PSSKPKEPM |
12.66
|
-5.23 |
-4.21 |
|
PPPSSKPKE |
13.94
|
-4.85 |
-3.82 |
|
RPSPPTAAT |
14.57
|
-4.61 |
-3.59 |
| P32448 |
PQLPSKDKS |
13.74
|
-3.53 |
-2.50 |
|
SPQLPSKDK |
15.08
|
-5.85 |
-4.82 |
|
RVPTDSPQL |
15.30
|
-4.75 |
-3.73 |
| P35197 |
RPDHLPPSQ |
13.08
|
-4.88 |
-3.86 |
|
NQSRPDHLP |
15.64
|
-7.01 |
-5.98 |
| Q12446 |
PQLPNRNNR |
12.30
|
-9.97 |
-8.95 |
|
PPPPPRASR |
12.42
|
-10.80 |
-9.78 |
|
PPPPHRHVT |
12.60
|
-9.37 |
-8.34 |
| P08018 |
PPPRLPSDK |
11.40
|
-10.34 |
-9.31 |
|
RAPRRPLST |
11.89
|
-8.07 |
-7.04 |
|
TQHPTRPNV |
12.74
|
-6.65 |
-5.63 |
| P39969 |
RRAPKPPSY |
13.61
|
-4.87 |
-3.85 |
|
PRRAPKPPS |
14.68
|
-4.97 |
-3.94 |
|
LPPQPGSKK |
14.83
|
-5.93 |
-4.90 |
| P09620 |
SNPISKPSI |
12.00
|
-5.37 |
-4.35 |
|
NPISKPSIH |
14.88
|
-4.37 |
-3.35 |
| Q03790 |
FPSAPQPLF |
15.83
|
-5.94 |
-4.92 |
| P39083 |
PATPSNVSM |
16.20
|
-4.84 |
-3.81 |
| Q06412 |
SPKSPRDSS |
14.13
|
-6.04 |
-5.02 |
|
RPPPPPPLL |
14.19
|
-8.54 |
-7.51 |
|
SPNSPKSPR |
14.30
|
-6.37 |
-5.35 |
|
