|
Matrix information:
(Help)
ADAN-name: SHO1_2VKN-14.PDB
Scoring matrix: SHO1_2VKN-14_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.48
Foldx random average score for Saccharomyces cerevisiae: 14.680 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5078
Total fragments: 850225
Proteins after disorder filtering: 2900
Total fragments: 28284
Proteins after pattern filtering: 1198
Total fragments: 3571
Proteins after MINT filtering: 20
Total fragments: 105 ROC parameters:
TPR= 0.357
FPR= 0.235
ACC= 0.761
SPC= 0.765
MCC= 0.03 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
18.48
|
-2.13 |
0.00 |
| Best peptides |
WPFRIRRLF |
0.00
|
-9.91 |
-7.78 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNSKY |
14.22
|
-6.28 |
-4.15 |
| Q06604 |
PPLPTRRDH |
8.84
|
-8.91 |
-6.78 |
|
PLLPTRPNK |
11.21
|
-7.67 |
-5.54 |
|
PTRPNKAEV |
11.51
|
-4.30 |
-2.17 |
| P24583 |
PPQPRKHDK |
9.82
|
-6.30 |
-4.17 |
|
LPPQPRKHD |
10.97
|
-6.27 |
-4.14 |
| P13186 |
LPEREPPTY |
11.75
|
-7.12 |
-4.99 |
|
APSYVPNRV |
13.67
|
-4.45 |
-2.32 |
|
IPLTPLATN |
13.85
|
-6.31 |
-4.18 |
| P22147 |
IPTPPHPMN |
11.32
|
-7.71 |
-5.58 |
|
LPYNIPPGF |
12.63
|
-6.11 |
-3.98 |
|
PPPAPHGFG |
12.65
|
-7.14 |
-5.01 |
| Q05080 |
KPDKPRPIV |
6.84
|
-9.41 |
-7.28 |
| Q08229 |
NPTIPPRSK |
12.34
|
-7.78 |
-5.65 |
|
PTIPPRSKD |
14.51
|
-2.99 |
-0.86 |
| P40036 |
PPLSPKSTV |
9.73
|
-6.49 |
-4.36 |
|
LPPLSPKST |
13.72
|
-7.30 |
-5.17 |
|
SLPTTPGIR |
14.26
|
-5.59 |
-3.46 |
| Q00246 |
NLPRLPTPF |
11.32
|
-6.37 |
-4.24 |
|
EKNLPRLPT |
11.46
|
-7.43 |
-5.30 |
| P53297 |
MPFQPQPMF |
10.51
|
-8.17 |
-6.04 |
|
MPQMMPVMG |
11.37
|
-7.87 |
-5.74 |
|
MFYHPSMPQ |
13.23
|
-5.83 |
-3.70 |
| Q04439 |
PSSKPKEPM |
11.15
|
-6.39 |
-4.26 |
|
PPPSSKPKE |
11.68
|
-4.98 |
-2.85 |
|
KPKEPMFEA |
14.03
|
-6.29 |
-4.16 |
| P32448 |
PQLPSKDKS |
13.85
|
-3.42 |
-1.29 |
|
SPQLPSKDK |
13.98
|
-6.60 |
-4.47 |
|
RVPTDSPQL |
14.33
|
-6.48 |
-4.35 |
| P35197 |
RPDHLPPSQ |
12.99
|
-6.11 |
-3.98 |
|
TPAKPPQER |
13.40
|
-6.41 |
-4.28 |
| Q12446 |
PPPPHRHVT |
9.49
|
-8.71 |
-6.58 |
|
PPPPPRASR |
9.59
|
-13.30 |
-11.17 |
|
PPPPMRTTT |
9.69
|
-9.87 |
-7.74 |
| P08018 |
PPPRLPSDK |
10.40
|
-9.04 |
-6.91 |
|
TQHPTRPNV |
11.49
|
-5.24 |
-3.11 |
|
RAPRRPLST |
11.76
|
-9.32 |
-7.19 |
| P39969 |
QPPKSPLLN |
12.89
|
-5.49 |
-3.36 |
|
PAQPPKSPL |
13.38
|
-5.33 |
-3.20 |
|
LSPIPSPTR |
13.55
|
-6.92 |
-4.79 |
| P09620 |
SNPISKPSI |
10.32
|
-5.91 |
-3.78 |
|
NPISKPSIH |
13.74
|
-5.08 |
-2.95 |
|
DPSNIPQMH |
14.10
|
-4.76 |
-2.63 |
| Q03790 |
FPSAPQPLF |
13.24
|
-7.96 |
-5.83 |
|
KPTATPSPF |
13.75
|
-5.65 |
-3.52 |
| Q06412 |
SPNSPKSPR |
11.39
|
-5.42 |
-3.29 |
|
SPKSPRDSS |
12.10
|
-5.73 |
-3.60 |
|
RPPPPPPLL |
13.11
|
-7.82 |
-5.69 |
| P38753 |
NLPIQHPTN |
9.56
|
-8.25 |
-6.12 |
|
TPVMPPQRQ |
13.94
|
-5.24 |
-3.11 |
|
NTPVMPPQR |
14.13
|
-7.13 |
-5.00 |
|
