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Matrix information:
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ADAN-name: SHO1_2VKN-12.PDB
Scoring matrix: SHO1_2VKN-12_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.21
Foldx random average score for Saccharomyces cerevisiae: 11.812 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 908660
Proteins after disorder filtering: 3177
Total fragments: 53035
Proteins after pattern filtering: 1506
Total fragments: 8726
Proteins after MINT filtering: 24
Total fragments: 296 ROC parameters:
TPR= 0.429
FPR= 0.295
ACC= 0.702
SPC= 0.705
MCC= 0.031 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
14.21
|
-1.36 |
0.00 |
| Best peptides |
WRIERRWK |
0.00
|
-8.39 |
-7.03 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNSK |
10.13
|
-5.76 |
-4.40 |
|
SKPLPLTP |
11.03
|
-5.76 |
-4.40 |
| Q06604 |
PRMPSRGR |
6.43
|
-8.16 |
-6.80 |
|
FEKGPRMP |
7.10
|
-3.88 |
-2.52 |
|
PLLPTRPN |
8.45
|
-6.45 |
-5.09 |
| P24583 |
LPPQPRKH |
8.19
|
-4.34 |
-2.98 |
|
PLPPQPRK |
9.43
|
-4.52 |
-3.16 |
|
RANAPLPP |
11.16
|
-3.24 |
-1.88 |
| Q06412 |
RRPPPPPP |
8.36
|
-5.08 |
-3.72 |
|
ERRPPPPP |
8.46
|
-4.79 |
-3.43 |
|
NGFSPNSP |
8.51
|
-3.84 |
-2.48 |
| P40036 |
IELPPLSP |
9.92
|
-6.42 |
-5.06 |
|
PTTPGIRS |
11.09
|
-4.28 |
-2.92 |
|
ELPPLSPK |
11.40
|
-3.60 |
-2.24 |
| P09620 |
SNPISKPS |
9.60
|
-4.01 |
-2.65 |
|
NPISKPSI |
10.29
|
-4.90 |
-3.54 |
|
PDPSNIPQ |
11.29
|
-2.52 |
-1.16 |
| P13186 |
PSYVPNRV |
6.61
|
-5.45 |
-4.09 |
|
EPLPEREP |
9.33
|
-5.97 |
-4.61 |
|
PEREPPTY |
9.45
|
-3.76 |
-2.40 |
| P32334 |
SSPSSPTT |
11.58
|
-2.64 |
-1.28 |
| P39083 |
QSPATPSN |
11.15
|
-3.02 |
-1.66 |
|
PATPSNVS |
11.28
|
-4.57 |
-3.21 |
| P38753 |
NLPIQHPT |
9.69
|
-4.31 |
-2.95 |
|
NTPVMPPQ |
9.84
|
-3.31 |
-1.95 |
|
SPYPSNLP |
10.08
|
-5.86 |
-4.50 |
| Q08229 |
PTIPPRSK |
4.88
|
-6.13 |
-4.77 |
|
YNPTIPPR |
10.36
|
-3.62 |
-2.26 |
|
PTPVQPGG |
10.77
|
-3.45 |
-2.09 |
| Q00246 |
KNLPRLPT |
9.90
|
-6.83 |
-5.47 |
|
EKNLPRLP |
9.96
|
-4.62 |
-3.26 |
|
PRLPTPFA |
10.02
|
-5.21 |
-3.85 |
| P32448 |
DSPQLPSK |
10.31
|
-2.68 |
-1.32 |
|
PQLPSKDK |
11.50
|
-5.56 |
-4.20 |
| Q04439 |
PTPPQNRD |
8.37
|
-5.64 |
-4.28 |
|
KPKEPMFE |
8.74
|
-4.17 |
-2.81 |
|
ANIPPPPP |
9.18
|
-5.20 |
-3.84 |
| P35197 |
SRPDHLPP |
7.22
|
-5.52 |
-4.16 |
|
STPAKPPQ |
10.03
|
-4.11 |
-2.75 |
|
PAKPPQER |
10.44
|
-4.99 |
-3.63 |
| Q12446 |
PPPPPRRG |
6.92
|
-5.85 |
-4.49 |
|
NRPVPPPP |
7.67
|
-4.40 |
-3.04 |
|
PPPPRRGP |
7.77
|
-5.95 |
-4.59 |
| P08018 |
DGPPPRLP |
7.28
|
-5.08 |
-3.72 |
|
TQHPTRPN |
8.15
|
-5.86 |
-4.50 |
|
GPPPRLPS |
9.77
|
-6.17 |
-4.81 |
| P39969 |
SSPEENPI |
7.92
|
-4.53 |
-3.17 |
|
PRRAPKPP |
8.22
|
-4.72 |
-3.36 |
|
PKPPSYPS |
9.40
|
-4.82 |
-3.46 |
| Q03790 |
ATPSPFRP |
9.29
|
-4.15 |
-2.79 |
|
GKPTATPS |
10.91
|
-3.54 |
-2.18 |
|
NGFPSAPQ |
10.96
|
-4.36 |
-3.00 |
| P41809 |
PYPSPNSY |
9.00
|
-4.46 |
-3.10 |
|
TYPTTPYP |
10.80
|
-3.49 |
-2.13 |
|
TPYPSPNS |
11.17
|
-4.51 |
-3.15 |
| Q05080 |
QKPDKPRP |
8.20
|
-5.12 |
-3.76 |
|
RQKPDKPR |
10.06
|
-4.18 |
-2.82 |
|
PDKPRPIV |
10.26
|
-4.68 |
-3.32 |
| P25344 |
PGPSPNEA |
9.72
|
-4.31 |
-2.95 |
| P53297 |
GAPEGKPP |
9.42
|
-3.28 |
-1.92 |
|
GMYMPFQP |
9.49
|
-4.59 |
-3.23 |
|
SMPQMMPV |
9.61
|
-4.44 |
-3.08 |
| P22147 |
ISFPPPPP |
9.23
|
-4.81 |
-3.45 |
|
GQPISFPP |
9.35
|
-4.01 |
-2.65 |
|
MSIPPPAP |
9.52
|
-4.90 |
-3.54 |
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