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Matrix information:
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ADAN-name: SHO1_2VKN-11.PDB
Scoring matrix: SHO1_2VKN-11_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 17.15
Foldx random average score for Saccharomyces cerevisiae: 14.372 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2186557
Proteins after random average filtering: 5078
Total fragments: 904455
Proteins after disorder filtering: 3285
Total fragments: 60698
Proteins after pattern filtering: 1586
Total fragments: 10300
Proteins after MINT filtering: 24
Total fragments: 335 ROC parameters:
TPR= 0.429
FPR= 0.311
ACC= 0.686
SPC= 0.689
MCC= 0.026 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
17.15
|
-1.87 |
0.00 |
| Best peptides |
WKPRFPR |
0.00
|
-7.63 |
-5.76 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTP |
11.70
|
-8.28 |
-6.41 |
|
PLTPNSK |
12.54
|
-5.40 |
-3.53 |
|
LPLTPNS |
13.62
|
-6.33 |
-4.46 |
| Q06604 |
LPTRPNK |
5.52
|
-9.23 |
-7.36 |
|
GPRMPSR |
6.80
|
-7.98 |
-6.11 |
|
KPLLPTR |
6.97
|
-9.56 |
-7.69 |
| P24583 |
LPPQPRK |
8.29
|
-8.16 |
-6.29 |
|
PLPPQPR |
9.70
|
-7.82 |
-5.95 |
|
NAPLPPQ |
12.99
|
-7.12 |
-5.25 |
| Q06412 |
NSPKSPR |
7.40
|
-3.85 |
-1.98 |
|
RPPPPPP |
9.67
|
-11.22 |
-9.35 |
|
FSPNSPK |
10.08
|
-4.23 |
-2.36 |
| P40036 |
LPPLSPK |
10.98
|
-5.68 |
-3.81 |
|
PTTPGIR |
11.73
|
-4.96 |
-3.09 |
|
LPTTPGI |
12.76
|
-6.16 |
-4.29 |
| P09620 |
PISKPSI |
10.35
|
-6.17 |
-4.30 |
|
DPSNIPQ |
12.58
|
-5.61 |
-3.74 |
|
PDPSNIP |
14.25
|
-4.44 |
-2.57 |
| P13186 |
PSYVPNR |
6.91
|
-7.89 |
-6.02 |
|
LPEREPP |
8.78
|
-8.40 |
-6.53 |
|
IPAALPP |
11.66
|
-8.10 |
-6.23 |
| P32334 |
SPSSPTT |
13.56
|
-5.03 |
-3.16 |
|
FSSPSSP |
13.56
|
-3.69 |
-1.82 |
| P39083 |
SPATPSN |
12.32
|
-5.42 |
-3.55 |
|
QSPATPS |
14.09
|
-2.40 |
-0.53 |
| P38753 |
PVMPPQR |
9.49
|
-8.15 |
-6.28 |
|
SPPVPGP |
10.45
|
-6.95 |
-5.08 |
|
YPSNLPI |
10.86
|
-8.14 |
-6.27 |
| Q08229 |
NPTIPPR |
8.36
|
-10.56 |
-8.69 |
|
YNPTIPP |
11.74
|
-6.84 |
-4.97 |
|
TPVQPGG |
13.06
|
-5.98 |
-4.11 |
| Q00246 |
NLPRLPT |
9.23
|
-7.76 |
-5.89 |
|
LPESPGT |
12.36
|
-7.03 |
-5.16 |
|
LPRLPTP |
12.84
|
-8.11 |
-6.24 |
| P32448 |
SPQLPSK |
10.33
|
-6.54 |
-4.67 |
|
RVPTDSP |
12.55
|
-6.38 |
-4.51 |
| Q04439 |
PPSSKPK |
9.87
|
-6.64 |
-4.77 |
|
KPAPPPP |
10.01
|
-10.45 |
-8.58 |
|
PTPPQNR |
10.02
|
-6.09 |
-4.22 |
| P35197 |
TPAKPPQ |
8.83
|
-7.87 |
-6.00 |
|
RPDHLPP |
11.32
|
-9.95 |
-8.08 |
|
PDHLPPS |
13.71
|
-7.07 |
-5.20 |
| Q12446 |
APPPPPR |
5.93
|
-10.57 |
-8.70 |
|
PPPPPRR |
6.14
|
-9.63 |
-7.76 |
|
PPPPPHR |
6.22
|
-11.58 |
-9.71 |
| P08018 |
PPPRLPS |
8.23
|
-9.26 |
-7.39 |
|
HPTRPNV |
8.58
|
-8.47 |
-6.60 |
|
APRRPLS |
8.79
|
-7.94 |
-6.07 |
| P39969 |
SPRRAPK |
6.72
|
-6.76 |
-4.89 |
|
PIPSPTR |
8.00
|
-7.39 |
-5.52 |
|
SPAQPPK |
8.79
|
-7.17 |
-5.30 |
| Q03790 |
FPSAPQP |
11.32
|
-8.19 |
-6.32 |
|
TPSPFRP |
11.66
|
-7.48 |
-5.61 |
|
PTATPSP |
12.97
|
-4.96 |
-3.09 |
| P41809 |
YPTTPYP |
11.34
|
-7.40 |
-5.53 |
|
SPSVPVA |
12.09
|
-6.40 |
-4.53 |
|
TTPYPSP |
12.27
|
-4.72 |
-2.85 |
| Q05080 |
QKPDKPR |
8.21
|
-6.97 |
-5.10 |
|
KPDKPRP |
9.06
|
-9.36 |
-7.49 |
|
PDKPRPI |
13.88
|
-5.54 |
-3.67 |
| P25344 |
NTPGPSP |
13.56
|
-3.81 |
-1.94 |
|
TPGPSPN |
14.00
|
-3.84 |
-1.97 |
| P53297 |
PPKPISK |
9.06
|
-8.14 |
-6.27 |
|
PEGKPPQ |
9.93
|
-6.96 |
-5.09 |
|
LPPKPIS |
10.17
|
-7.72 |
-5.85 |
| P22147 |
FPPPPPM |
8.63
|
-9.62 |
-7.75 |
|
TPPHPMN |
11.11
|
-7.34 |
-5.47 |
|
HPLHPHQ |
11.23
|
-5.94 |
-4.07 |
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