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Matrix information:
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ADAN-name: SHO1_2VKN-10.PDB
Scoring matrix: SHO1_2VKN-10_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 16.13
Foldx random average score for Saccharomyces cerevisiae: 12.601 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 942723
Proteins after disorder filtering: 3236
Total fragments: 65913
Proteins after pattern filtering: 1596
Total fragments: 11277
Proteins after MINT filtering: 24
Total fragments: 407 ROC parameters:
TPR= 0.429
FPR= 0.313
ACC= 0.684
SPC= 0.687
MCC= 0.026 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
16.13
|
-2.50 |
0.00 |
| Best peptides |
RPRRDWRP |
0.00
|
-9.25 |
-6.75 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLTPNSKY |
8.63
|
-5.76 |
-3.26 |
|
LPLTPNSK |
10.33
|
-6.97 |
-4.47 |
|
SKPLPLTP |
10.86
|
-4.67 |
-2.17 |
| Q06604 |
KPLLPTRP |
4.25
|
-10.50 |
-8.00 |
|
LPTRPNKA |
5.84
|
-9.02 |
-6.52 |
|
PPPLPTRR |
5.96
|
-9.55 |
-7.05 |
| P24583 |
LPPQPRKH |
5.87
|
-10.10 |
-7.60 |
|
PLPPQPRK |
8.28
|
-7.35 |
-4.85 |
|
PPQPRKHD |
9.88
|
-6.96 |
-4.46 |
| Q06412 |
RPPPPPPL |
6.94
|
-9.92 |
-7.42 |
|
RRPPPPPP |
7.51
|
-8.57 |
-6.07 |
|
PPPPPPLL |
7.92
|
-8.12 |
-5.62 |
| P40036 |
LPTTPGIR |
8.16
|
-8.38 |
-5.88 |
|
LPPLSPKS |
8.72
|
-6.95 |
-4.45 |
|
IELPPLSP |
10.73
|
-7.19 |
-4.69 |
| P09620 |
PISKPSIH |
8.40
|
-6.69 |
-4.19 |
|
PSNIPQMH |
9.56
|
-7.27 |
-4.77 |
|
VPDPSNIP |
11.71
|
-4.34 |
-1.84 |
| P13186 |
RPPIPAAL |
6.66
|
-9.66 |
-7.16 |
|
PSYVPNRV |
8.29
|
-7.96 |
-5.46 |
|
IPMSPNYG |
9.12
|
-7.08 |
-4.58 |
| P32334 |
SPSSPTTT |
11.32
|
-5.03 |
-2.53 |
|
DFSSPSSP |
12.48
|
-4.22 |
-1.72 |
| P39083 |
SPATPSNV |
10.53
|
-5.86 |
-3.36 |
|
LLQSPATP |
11.52
|
-5.50 |
-3.00 |
| P38753 |
PVMPPQRQ |
7.47
|
-8.89 |
-6.39 |
|
TPVMPPQR |
8.03
|
-7.69 |
-5.19 |
|
ANNTPVMP |
9.86
|
-6.77 |
-4.27 |
| Q08229 |
NPTIPPRS |
4.93
|
-10.63 |
-8.13 |
|
NDYNPTIP |
9.91
|
-5.63 |
-3.13 |
|
TPVQPGGH |
10.21
|
-6.49 |
-3.99 |
| Q00246 |
LPRLPTPF |
9.38
|
-7.92 |
-5.42 |
|
EKNLPRLP |
9.41
|
-6.72 |
-4.22 |
|
LPESPGTL |
10.03
|
-6.21 |
-3.71 |
| P32448 |
SPQLPSKD |
7.71
|
-8.46 |
-5.96 |
|
RVPTDSPQ |
8.85
|
-6.31 |
-3.81 |
|
PTDSPQLP |
11.55
|
-5.64 |
-3.14 |
| Q04439 |
KPKEPMFE |
6.95
|
-7.77 |
-5.27 |
|
RPSPPTAA |
6.95
|
-8.77 |
-6.27 |
|
APPPPGMQ |
7.65
|
-7.88 |
-5.38 |
| P35197 |
TPAKPPQE |
7.36
|
-8.71 |
-6.21 |
|
FGSTPAKP |
8.07
|
-6.65 |
-4.15 |
|
QSRPDHLP |
8.97
|
-4.10 |
-1.60 |
| Q12446 |
APPPPPRR |
5.32
|
-10.01 |
-7.51 |
|
APPPPPRA |
5.53
|
-9.61 |
-7.11 |
|
PPPPPRRG |
5.58
|
-10.09 |
-7.59 |
| P08018 |
RAPRRPLS |
6.61
|
-7.03 |
-4.53 |
|
STQHPTRP |
8.21
|
-8.17 |
-5.67 |
|
RPNVAPHK |
8.33
|
-7.68 |
-5.18 |
| P39969 |
FKLLPPQP |
7.00
|
-8.24 |
-5.74 |
|
APKPPSYP |
7.02
|
-6.95 |
-4.45 |
|
SPAQPPKS |
7.07
|
-7.74 |
-5.24 |
| Q03790 |
ATPSPFRP |
8.23
|
-7.24 |
-4.74 |
|
FPSAPQPL |
9.98
|
-7.24 |
-4.74 |
|
LNGFPSAP |
10.98
|
-5.96 |
-3.46 |
| P41809 |
YPTTPYPS |
9.54
|
-7.39 |
-4.89 |
|
YTSSPSVP |
10.43
|
-5.18 |
-2.68 |
|
SPSVPVAV |
10.44
|
-6.27 |
-3.77 |
| Q05080 |
LRQKPDKP |
6.54
|
-9.53 |
-7.03 |
|
RQKPDKPR |
7.70
|
-5.68 |
-3.18 |
|
KPDKPRPI |
8.11
|
-7.44 |
-4.94 |
| P25344 |
TPGPSPNE |
11.65
|
-3.39 |
-0.89 |
| P53297 |
MFYHPSMP |
7.04
|
-8.92 |
-6.42 |
|
HPSMPQMM |
7.84
|
-8.36 |
-5.86 |
|
LPPKPISK |
8.05
|
-7.96 |
-5.46 |
| P22147 |
FPPPPPMT |
4.78
|
-10.71 |
-8.21 |
|
HPHQMPYP |
6.47
|
-7.19 |
-4.69 |
|
HPLHPHQM |
8.34
|
-8.54 |
-6.04 |
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