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Matrix information:
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ADAN-name: SHO1_1QKX-9.PDB
Scoring matrix: SHO1_1QKX-9_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 13.09
Foldx random average score for Saccharomyces cerevisiae: 11.544 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 931381
Proteins after disorder filtering: 3144
Total fragments: 41021
Proteins after pattern filtering: 1455
Total fragments: 6666
Proteins after MINT filtering: 23
Total fragments: 193 ROC parameters:
TPR= 0.411
FPR= 0.285
ACC= 0.712
SPC= 0.715
MCC= 0.029 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
13.09
|
0.88 |
0.00 |
| Best peptides |
LDWRPEKY |
0.00
|
1.11 |
0.23 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
SKPLPLTP |
11.10
|
-5.85 |
-6.73 |
|
PLTPNSKY |
11.41
|
-5.72 |
-6.60 |
| Q06604 |
KGPRMPSR |
4.79
|
-5.93 |
-6.81 |
|
LPTRPNKA |
7.85
|
-5.46 |
-6.34 |
|
NEEKPLLP |
8.20
|
-6.75 |
-7.63 |
| P24583 |
RANAPLPP |
8.76
|
-6.88 |
-7.76 |
|
LPPQPRKH |
10.19
|
-5.74 |
-6.62 |
|
PLPPQPRK |
10.21
|
-6.97 |
-7.85 |
| Q06412 |
KERRPPPP |
4.18
|
-8.94 |
-9.82 |
|
FFTKPPPP |
5.74
|
-8.58 |
-9.46 |
|
RRPPPPPP |
8.33
|
-9.55 |
-10.43 |
| P40036 |
LPTTPGIR |
10.57
|
-5.75 |
-6.63 |
|
IELPPLSP |
11.23
|
-5.12 |
-6.00 |
|
SLPTTPGI |
11.32
|
-5.33 |
-6.21 |
| P09620 |
PSNIPQMH |
10.05
|
-6.49 |
-7.37 |
|
PISKPSIH |
11.09
|
-7.35 |
-8.23 |
|
PDPSNIPQ |
11.32
|
-3.58 |
-4.46 |
| P13186 |
QQQAPLMP |
8.76
|
-6.36 |
-7.24 |
|
PSYVPNRV |
8.78
|
-5.72 |
-6.60 |
|
LPEREPPT |
9.16
|
-3.71 |
-4.59 |
| P39083 |
LLQSPATP |
9.24
|
-6.01 |
-6.89 |
| P38753 |
AHISPPVP |
8.53
|
-5.07 |
-5.95 |
|
ANNTPVMP |
10.12
|
-5.71 |
-6.59 |
|
PVPGPALY |
10.53
|
-5.23 |
-6.11 |
| Q08229 |
NDYNPTIP |
10.51
|
-4.76 |
-5.64 |
|
YNPTIPPR |
10.81
|
-5.08 |
-5.96 |
| Q00246 |
NLPRLPTP |
7.27
|
-7.30 |
-8.18 |
|
EKNLPRLP |
9.83
|
-6.73 |
-7.61 |
|
SSNLPESP |
11.33
|
-3.96 |
-4.84 |
| P32448 |
DSPQLPSK |
10.86
|
-3.70 |
-4.58 |
| Q04439 |
KKPAPPPP |
6.66
|
-8.32 |
-9.20 |
|
SNARPSPP |
8.05
|
-5.00 |
-5.88 |
|
SKPKEPMF |
8.23
|
-5.67 |
-6.55 |
| P35197 |
FGSTPAKP |
6.57
|
-6.43 |
-7.31 |
|
PDHLPPSQ |
10.27
|
-6.30 |
-7.18 |
| Q12446 |
PFPIPEIP |
5.91
|
-7.75 |
-8.63 |
|
KHKAPPPP |
6.03
|
-6.09 |
-6.97 |
|
RNNRPVPP |
6.27
|
-7.39 |
-8.27 |
| P08018 |
RAPRRPLS |
5.77
|
-7.71 |
-8.59 |
|
QHPTRPNV |
9.82
|
-3.84 |
-4.72 |
|
DGPPPRLP |
9.91
|
-5.20 |
-6.08 |
| P39969 |
RAPKPPSY |
7.71
|
-7.63 |
-8.51 |
|
FKLLPPQP |
8.15
|
-8.57 |
-9.45 |
|
VSPRRAPK |
8.21
|
-3.55 |
-4.43 |
| Q03790 |
LNGFPSAP |
9.81
|
-4.10 |
-4.98 |
|
GFPSAPQP |
10.13
|
-4.73 |
-5.61 |
|
ATPSPFRP |
10.32
|
-6.21 |
-7.09 |
| P41809 |
PYPSPNSY |
9.09
|
-3.61 |
-4.49 |
|
TYPTTPYP |
9.82
|
-5.69 |
-6.57 |
|
LSTYPTTP |
10.72
|
-4.45 |
-5.33 |
| Q05080 |
LRQKPDKP |
6.36
|
-7.44 |
-8.32 |
|
PDKPRPIV |
9.30
|
-5.45 |
-6.33 |
|
QKPDKPRP |
10.54
|
-7.14 |
-8.02 |
| P25344 |
PGPSPNEA |
10.44
|
-2.41 |
-3.29 |
| P53297 |
YHPSMPQM |
6.57
|
-5.51 |
-6.39 |
|
MFYHPSMP |
7.16
|
-7.96 |
-8.84 |
|
PEGKPPQK |
8.31
|
-7.76 |
-8.64 |
| P22147 |
LHPHQMPY |
7.76
|
-2.39 |
-3.27 |
|
SFPPPPPM |
8.28
|
-6.79 |
-7.67 |
|
PYNIPPGF |
8.42
|
-6.06 |
-6.94 |
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