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Matrix information:
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ADAN-name: SHO1_1QKX-8.PDB
Scoring matrix: SHO1_1QKX-8_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.13
Foldx random average score for Saccharomyces cerevisiae: 12.131 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 855061
Proteins after disorder filtering: 3091
Total fragments: 50122
Proteins after pattern filtering: 1439
Total fragments: 7087
Proteins after MINT filtering: 21
Total fragments: 229 ROC parameters:
TPR= 0.375
FPR= 0.282
ACC= 0.714
SPC= 0.718
MCC= 0.021 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
15.13
|
0.89 |
0.00 |
| Best peptides |
KWFWKFER |
0.00
|
0.74 |
-0.15 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLTPNSKY |
10.91
|
-3.75 |
-4.64 |
|
LPLTPNSK |
11.64
|
-3.77 |
-4.66 |
| Q06604 |
PRMPSRGR |
5.99
|
-5.11 |
-6.00 |
|
KGPRMPSR |
7.65
|
-6.47 |
-7.36 |
|
KNKPKPTP |
7.85
|
-4.67 |
-5.56 |
| P24583 |
APLPPQPR |
8.60
|
-5.95 |
-6.84 |
|
ANAPLPPQ |
10.73
|
-4.40 |
-5.29 |
|
PLPPQPRK |
11.03
|
-2.85 |
-3.74 |
| P13186 |
APSYVPNR |
8.80
|
-5.22 |
-6.11 |
|
SIPMSPNY |
9.47
|
-1.86 |
-2.75 |
|
PEREPPTY |
9.89
|
-3.41 |
-4.30 |
| P41809 |
PYPSPNSY |
9.43
|
-1.68 |
-2.57 |
|
STYPTTPY |
11.06
|
-4.60 |
-5.49 |
|
TPYPSPNS |
11.54
|
-2.75 |
-3.64 |
| Q05080 |
QKPDKPRP |
8.40
|
-3.24 |
-4.13 |
|
RQKPDKPR |
8.83
|
-5.31 |
-6.20 |
|
KPDKPRPI |
9.84
|
-4.66 |
-5.55 |
| Q08229 |
YNPTIPPR |
7.66
|
-2.75 |
-3.64 |
| P40036 |
LPTTPGIR |
11.21
|
-2.32 |
-3.21 |
|
PLSPKSTV |
11.32
|
-1.99 |
-2.88 |
| Q00246 |
KNLPRLPT |
8.67
|
-6.40 |
-7.29 |
|
LPRLPTPF |
9.66
|
-3.63 |
-4.52 |
|
EKNLPRLP |
11.55
|
-3.07 |
-3.96 |
| P53297 |
APEGKPPQ |
7.86
|
-5.08 |
-5.97 |
|
MYMPFQPQ |
8.07
|
-3.97 |
-4.86 |
|
FYHPSMPQ |
8.60
|
-3.73 |
-4.62 |
| P22147 |
PYNIPPGF |
8.52
|
-5.66 |
-6.55 |
|
GLHPLHPH |
9.66
|
-4.37 |
-5.26 |
|
LHPHQMPY |
9.98
|
-1.64 |
-2.53 |
| P32448 |
PQLPSKDK |
11.01
|
-4.83 |
-5.72 |
|
VPTDSPQL |
11.59
|
-3.39 |
-4.28 |
| P35197 |
PAKPPQER |
7.88
|
-4.66 |
-5.55 |
|
STPAKPPQ |
9.37
|
-2.19 |
-3.08 |
|
SRPDHLPP |
10.99
|
-3.97 |
-4.86 |
| Q12446 |
PPPPRASR |
7.50
|
-4.68 |
-5.57 |
|
APPPPPRR |
8.05
|
-4.37 |
-5.26 |
|
VPPPPPMR |
8.26
|
-3.78 |
-4.67 |
| P08018 |
GPPPRLPS |
9.49
|
-3.92 |
-4.81 |
|
PRLPSDKF |
9.63
|
-3.42 |
-4.31 |
|
PPRLPSDK |
10.74
|
-3.18 |
-4.07 |
| P39969 |
RRAPKPPS |
7.44
|
-5.76 |
-6.65 |
|
SPIPSPTR |
8.52
|
-5.92 |
-6.81 |
|
AQPPKSPL |
9.23
|
-1.48 |
-2.37 |
| P09620 |
NPISKPSI |
8.79
|
-5.08 |
-5.97 |
|
VPDPSNIP |
10.79
|
-2.84 |
-3.73 |
|
PISKPSIH |
11.19
|
-1.65 |
-2.54 |
| Q03790 |
PSAPQPLF |
10.88
|
-3.63 |
-4.52 |
|
NGFPSAPQ |
10.92
|
-3.78 |
-4.67 |
|
PTATPSPF |
11.84
|
-1.75 |
-2.64 |
| Q04439 |
SSKPKEPM |
7.12
|
-4.26 |
-5.15 |
|
PKEPMFEA |
9.00
|
-4.76 |
-5.65 |
|
SKKPAPPP |
9.36
|
-4.27 |
-5.16 |
| Q06412 |
PNSPKSPR |
5.36
|
-4.55 |
-5.44 |
|
ERRPPPPP |
9.20
|
-4.58 |
-5.47 |
|
PKSPRDSS |
9.85
|
-5.42 |
-6.31 |
| P38753 |
TPVMPPQR |
9.21
|
-6.31 |
-7.20 |
|
PYPSNLPI |
9.23
|
-2.26 |
-3.15 |
|
SPYPSNLP |
10.72
|
-3.25 |
-4.14 |
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