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Matrix information:
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ADAN-name: SHO1_1QKX-7.PDB
Scoring matrix: SHO1_1QKX-7_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 12.44
Foldx random average score for Saccharomyces cerevisiae: 10.053 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 867045
Proteins after disorder filtering: 3185
Total fragments: 54176
Proteins after pattern filtering: 1562
Total fragments: 10904
Proteins after MINT filtering: 23
Total fragments: 370 ROC parameters:
TPR= 0.411
FPR= 0.306
ACC= 0.69
SPC= 0.694
MCC= 0.024 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AGAAAAAA |
12.44
|
-3.63 |
0.00 |
| Best peptides |
MPRREPFR |
0.00
|
1.22 |
4.85 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPN |
9.08
|
-5.98 |
-2.35 |
|
PLTPNSKY |
9.28
|
-3.57 |
0.06 |
|
PLPLTPNS |
9.47
|
-3.12 |
0.51 |
| Q06604 |
PPPLPTRR |
4.36
|
-7.12 |
-3.49 |
|
PPSPPAKR |
5.53
|
-6.54 |
-2.91 |
|
GPRMPSRG |
6.58
|
-7.51 |
-3.88 |
| P24583 |
PLPPQPRK |
5.57
|
-6.17 |
-2.54 |
|
APLPPQPR |
6.91
|
-5.45 |
-1.82 |
|
NAPLPPQP |
8.09
|
-5.82 |
-2.19 |
| Q06412 |
RPPPPPPL |
4.91
|
-7.34 |
-3.71 |
|
PPPPPPLL |
5.25
|
-8.45 |
-4.82 |
|
PPPPPLLY |
5.47
|
-7.94 |
-4.31 |
| P40036 |
ELPPLSPK |
7.49
|
-5.32 |
-1.69 |
|
PPLSPKST |
8.53
|
-3.70 |
-0.07 |
|
PLSPKSTV |
9.74
|
-4.85 |
-1.22 |
| P09620 |
PISKPSIH |
5.88
|
-6.07 |
-2.44 |
|
DPSNIPQM |
9.14
|
-3.10 |
0.53 |
|
NPISKPSI |
9.19
|
-3.47 |
0.16 |
| P13186 |
NIPLTPLA |
7.86
|
-3.45 |
0.18 |
|
PAALPPSD |
8.02
|
-4.52 |
-0.89 |
|
RPPIPAAL |
8.08
|
-4.82 |
-1.19 |
| P32334 |
SPSSPTTT |
9.44
|
-2.06 |
1.57 |
| P38753 |
TPVMPPQR |
4.62
|
-5.29 |
-1.66 |
|
YPSNLPIQ |
5.71
|
-6.26 |
-2.63 |
|
PSNLPIQH |
6.94
|
-5.04 |
-1.41 |
| Q08229 |
TPVQPGGH |
6.98
|
-1.95 |
1.68 |
|
NPTIPPRS |
8.09
|
-6.11 |
-2.48 |
|
PTIPPRSK |
8.19
|
-5.17 |
-1.54 |
| Q00246 |
NLPRLPTP |
7.77
|
-5.99 |
-2.36 |
|
EKNLPRLP |
7.89
|
-5.29 |
-1.66 |
|
PRLPTPFA |
8.30
|
-4.85 |
-1.22 |
| P32448 |
SPQLPSKD |
7.33
|
-4.54 |
-0.91 |
|
TDSPQLPS |
8.28
|
-1.55 |
2.08 |
|
DSPQLPSK |
8.32
|
-4.84 |
-1.21 |
| Q04439 |
RPSPPTAA |
6.71
|
-4.79 |
-1.16 |
|
SKPKEPMF |
6.71
|
-5.73 |
-2.10 |
|
PPPPPPPS |
6.72
|
-6.74 |
-3.11 |
| P35197 |
RPDHLPPS |
5.06
|
-7.16 |
-3.53 |
|
TPAKPPQE |
5.93
|
-4.01 |
-0.38 |
|
PDHLPPSQ |
7.70
|
-5.00 |
-1.37 |
| Q12446 |
APPPPPRR |
4.35
|
-7.23 |
-3.60 |
|
PPPPPAFL |
5.14
|
-7.35 |
-3.72 |
|
APPPPPHR |
5.30
|
-7.37 |
-3.74 |
| P08018 |
RAPRRPLS |
4.24
|
-6.79 |
-3.16 |
|
HPTRPNVA |
5.93
|
-4.95 |
-1.32 |
|
PPPRLPSD |
5.99
|
-6.36 |
-2.73 |
| P39969 |
RAPKPPSY |
5.33
|
-5.45 |
-1.82 |
|
PPKSPLLN |
6.45
|
-6.58 |
-2.95 |
|
SPAQPPKS |
6.80
|
-5.78 |
-2.15 |
| Q03790 |
PSAPQPLF |
6.62
|
-5.97 |
-2.34 |
|
FPSAPQPL |
7.64
|
-4.69 |
-1.06 |
|
ATPSPFRP |
8.42
|
-4.09 |
-0.46 |
| P41809 |
TTPYPSPN |
7.15
|
-2.97 |
0.66 |
|
YPTTPYPS |
8.33
|
-3.55 |
0.08 |
|
PYPSPNSY |
8.73
|
-3.30 |
0.33 |
| Q05080 |
PDKPRPIV |
7.24
|
-5.48 |
-1.85 |
|
KPDKPRPI |
8.18
|
-5.46 |
-1.83 |
|
RQKPDKPR |
8.20
|
-4.49 |
-0.86 |
| P25344 |
PGPSPNEA |
9.53
|
-3.70 |
-0.07 |
| P53297 |
MPQMMPVM |
5.33
|
-7.86 |
-4.23 |
|
MPFQPQPM |
5.75
|
-5.47 |
-1.84 |
|
HPSMPQMM |
6.00
|
-6.92 |
-3.29 |
| P22147 |
FPPPPPMT |
5.34
|
-6.71 |
-3.08 |
|
HPLHPHQM |
5.43
|
-6.79 |
-3.16 |
|
TPPHPMNV |
6.11
|
-3.58 |
0.05 |
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