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Matrix information:
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ADAN-name: SHO1_1QKX-29.PDB
Scoring matrix: SHO1_1QKX-29_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 24.48
Foldx random average score for Saccharomyces cerevisiae: 20.615 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2171323
Proteins after random average filtering: 5078
Total fragments: 931220
Proteins after disorder filtering: 3040
Total fragments: 53471
Proteins after pattern filtering: 1531
Total fragments: 11801
Proteins after MINT filtering: 23
Total fragments: 434 ROC parameters:
TPR= 0.411
FPR= 0.3
ACC= 0.697
SPC= 0.7
MCC= 0.025 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
24.48
|
5.03 |
0.00 |
| Best peptides |
HMPERIERRR |
0.00
|
0.70 |
-4.33 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLTPNSKYNG |
17.61
|
-2.36 |
-7.38 |
|
LPLTPNSKYN |
18.63
|
-1.50 |
-6.53 |
|
SKPLPLTPNS |
18.70
|
-4.55 |
-9.57 |
| Q06604 |
EKGPRMPSRG |
11.01
|
-5.81 |
-10.84 |
|
SPPPLPTRRD |
11.25
|
-7.22 |
-12.25 |
|
EKPLLPTRPN |
12.68
|
-9.24 |
-14.27 |
| P24583 |
APLPPQPRKH |
13.30
|
-6.44 |
-11.47 |
|
PLPPQPRKHD |
14.86
|
-8.62 |
-13.65 |
|
NAPLPPQPRK |
17.23
|
-5.71 |
-10.73 |
| Q06412 |
YVKERRPPPP |
12.53
|
-6.55 |
-11.57 |
|
EFFTKPPPPL |
13.86
|
-5.78 |
-10.81 |
|
PNSPKSPRDS |
14.23
|
-3.86 |
-8.88 |
| P40036 |
ELPPLSPKST |
13.53
|
-5.90 |
-10.93 |
|
SLPTTPGIRS |
16.58
|
-7.41 |
-12.44 |
|
KSLPTTPGIR |
17.41
|
-2.91 |
-7.94 |
| P09620 |
PDPSNIPQMH |
14.78
|
-4.40 |
-9.43 |
|
KLSNPISKPS |
15.86
|
-3.87 |
-8.89 |
|
VPDPSNIPQM |
16.54
|
-1.12 |
-6.15 |
| P13186 |
PLPEREPPTY |
11.40
|
-5.55 |
-10.57 |
|
SIPMSPNYGN |
15.48
|
-6.41 |
-11.44 |
|
KAPSYVPNRV |
15.68
|
-4.72 |
-9.75 |
| P32334 |
DFSSPSSPTT |
19.93
|
-0.04 |
-5.07 |
| P39083 |
DHLLQSPATP |
19.11
|
-2.77 |
-7.79 |
|
LLQSPATPSN |
19.98
|
-2.73 |
-7.76 |
| P38753 |
NTPVMPPQRQ |
14.34
|
-6.12 |
-11.15 |
|
NNTPVMPPQR |
15.00
|
-4.30 |
-9.32 |
|
PYPSNLPIQH |
15.22
|
-3.62 |
-8.64 |
| Q08229 |
YNPTIPPRSK |
9.67
|
-7.66 |
-12.69 |
|
DYNPTIPPRS |
12.21
|
-2.43 |
-7.46 |
|
PVQPGGHYKN |
17.94
|
-4.25 |
-9.28 |
| Q00246 |
KNLPRLPTPF |
13.40
|
-7.30 |
-12.32 |
|
NLPRLPTPFA |
18.59
|
-6.58 |
-11.61 |
|
SNLPESPGTL |
18.62
|
-2.40 |
-7.43 |
| P32448 |
PQLPSKDKSQ |
18.22
|
-5.01 |
-10.04 |
|
PRVPTDSPQL |
18.75
|
-4.14 |
-9.16 |
|
TDSPQLPSKD |
18.92
|
-2.99 |
-8.02 |
| Q04439 |
GRQANIPPPP |
14.30
|
-3.77 |
-8.79 |
|
NIPPPPPPPP |
15.02
|
-9.23 |
-14.26 |
|
SKKPAPPPPG |
15.49
|
-7.00 |
-12.03 |
| P35197 |
SRPDHLPPSQ |
15.09
|
-5.15 |
-10.18 |
|
PAKPPQERSA |
17.08
|
-4.41 |
-9.44 |
|
STPAKPPQER |
17.79
|
-6.99 |
-12.02 |
| Q12446 |
PPPPRASRPT |
9.17
|
-7.67 |
-12.70 |
|
PAPPPPPRRG |
11.29
|
-9.15 |
-14.18 |
|
RLPAPPPPPR |
13.40
|
-8.31 |
-13.34 |
| P08018 |
IVDGPPPRLP |
14.58
|
-10.10 |
-15.13 |
|
GPPPRLPSDK |
14.78
|
-5.01 |
-10.04 |
|
RAPRRPLSTQ |
16.85
|
-5.21 |
-10.23 |
| P39969 |
VSPRRAPKPP |
13.75
|
-6.38 |
-11.41 |
|
AQPPKSPLLN |
15.17
|
-4.99 |
-10.02 |
|
LLPPQPGSKK |
15.52
|
-5.87 |
-10.90 |
| Q03790 |
GFPSAPQPLF |
16.92
|
-4.96 |
-9.98 |
|
GKPTATPSPF |
18.06
|
-4.65 |
-9.68 |
|
GLNGFPSAPQ |
18.06
|
-4.27 |
-9.29 |
| P41809 |
STYPTTPYPS |
16.13
|
-4.22 |
-9.25 |
|
TYPTTPYPSP |
18.86
|
-4.15 |
-9.18 |
|
SSPSAPVAIS |
18.96
|
-5.54 |
-10.57 |
| Q05080 |
RQKPDKPRPI |
14.16
|
-5.47 |
-10.50 |
|
QKPDKPRPIV |
14.37
|
-7.74 |
-12.77 |
|
PDKPRPIVGE |
18.29
|
-4.19 |
-9.21 |
| P53297 |
AVPGMNPAMG |
12.40
|
-5.24 |
-10.27 |
|
SMPQMMPVMG |
13.56
|
-7.85 |
-12.88 |
|
SNSSLPPKPI |
14.86
|
-4.89 |
-9.91 |
| P22147 |
LHPHQMPYPN |
11.53
|
-5.92 |
-10.95 |
|
GLPYNIPPGF |
13.74
|
-6.53 |
-11.56 |
|
GQPISFPPPP |
13.98
|
-5.53 |
-10.56 |
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