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Matrix information:
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ADAN-name: SHO1_1QKX-28.PDB
Scoring matrix: SHO1_1QKX-28_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.82
Foldx random average score for Saccharomyces cerevisiae: 18.934 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2171323
Proteins after random average filtering: 5078
Total fragments: 1101549
Proteins after disorder filtering: 3137
Total fragments: 62922
Proteins after pattern filtering: 1512
Total fragments: 9345
Proteins after MINT filtering: 24
Total fragments: 365 ROC parameters:
TPR= 0.429
FPR= 0.296
ACC= 0.701
SPC= 0.704
MCC= 0.03 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAAA |
19.82
|
1.21 |
0.00 |
| Best peptides |
WPHRFPRRFV |
0.00
|
-3.65 |
-4.86 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNSKYN |
12.71
|
-7.15 |
-8.36 |
|
KPLPLTPNSK |
16.24
|
-6.22 |
-7.43 |
|
SKPLPLTPNS |
17.23
|
-3.41 |
-4.62 |
| Q06604 |
LPTRPNKAEV |
8.18
|
-10.72 |
-11.93 |
|
KPAPPVSRST |
11.48
|
-5.89 |
-7.10 |
|
PPPLPTRRDH |
11.88
|
-9.87 |
-11.08 |
| P24583 |
LPPQPRKHDK |
14.65
|
-8.08 |
-9.29 |
|
APLPPQPRKH |
14.90
|
-6.41 |
-7.62 |
|
PPQPRKHDKT |
15.49
|
-5.82 |
-7.03 |
| Q06412 |
FFTKPPPPLS |
13.58
|
-6.85 |
-8.06 |
|
FTKPPPPLST |
14.24
|
-6.53 |
-7.74 |
|
PPPPPLLYST |
14.34
|
-6.89 |
-8.10 |
| P40036 |
LPPLSPKSTV |
12.61
|
-9.04 |
-10.25 |
|
LPTTPGIRSG |
13.21
|
-7.39 |
-8.60 |
|
IELPPLSPKS |
15.12
|
-4.82 |
-6.03 |
| P09620 |
LSNPISKPSI |
15.89
|
-9.09 |
-10.30 |
|
PDPSNIPQMH |
15.96
|
-7.88 |
-9.09 |
|
VPDPSNIPQM |
16.02
|
-6.72 |
-7.93 |
| P13186 |
KAPSYVPNRV |
12.57
|
-10.03 |
-11.24 |
|
IPMSPNYGNQ |
13.17
|
-4.93 |
-6.14 |
|
IPLTPLATNT |
14.50
|
-4.48 |
-5.69 |
| P32334 |
SPSSPTTTDI |
14.70
|
-5.47 |
-6.68 |
|
DFSSPSSPTT |
15.69
|
-3.22 |
-4.43 |
|
FSSPSSPTTT |
16.70
|
-4.62 |
-5.83 |
| P39083 |
SPATPSNVSM |
14.53
|
-4.40 |
-5.61 |
|
LQSPATPSNV |
15.39
|
-7.02 |
-8.23 |
|
LLQSPATPSN |
17.92
|
-6.08 |
-7.29 |
| P38753 |
TPVMPPQRQS |
13.49
|
-6.80 |
-8.01 |
|
LPIQHPTNSA |
15.83
|
-6.72 |
-7.93 |
|
PIQHPTNSAN |
15.98
|
-8.94 |
-10.15 |
| Q08229 |
NPTIPPRSKD |
14.82
|
-6.33 |
-7.54 |
|
YNPTIPPRSK |
16.56
|
-5.54 |
-6.75 |
|
PSTPNEDSRV |
16.76
|
-7.12 |
-8.33 |
| Q00246 |
NLPRLPTPFA |
14.17
|
-6.57 |
-7.78 |
|
LPESPGTLDE |
16.69
|
-3.80 |
-5.01 |
|
SSNLPESPGT |
17.51
|
-5.15 |
-6.36 |
| P32448 |
SPQLPSKDKS |
16.01
|
-5.25 |
-6.46 |
|
TDSPQLPSKD |
17.92
|
-2.15 |
-3.36 |
|
PTDSPQLPSK |
18.23
|
-2.88 |
-4.09 |
| Q04439 |
IPTPPQNRDV |
11.23
|
-10.73 |
-11.94 |
|
SNARPSPPTA |
12.37
|
-4.48 |
-5.69 |
|
KPAPPPPGMQ |
12.81
|
-6.69 |
-7.90 |
| P35197 |
RPDHLPPSQG |
13.66
|
-8.28 |
-9.49 |
|
TPAKPPQERS |
15.20
|
-4.60 |
-5.81 |
|
PAKPPQERSA |
16.16
|
-6.33 |
-7.54 |
| Q12446 |
APPPPPHRHV |
10.44
|
-8.42 |
-9.63 |
|
PPPPPMRTTT |
11.54
|
-9.99 |
-11.20 |
|
PPPPPHRHVT |
11.67
|
-7.52 |
-8.73 |
| P08018 |
RAPRRPLSTQ |
10.76
|
-5.36 |
-6.57 |
|
APRRPLSTQH |
11.99
|
-7.00 |
-8.21 |
|
STQHPTRPNV |
12.19
|
-8.58 |
-9.79 |
| P39969 |
PIPSPTRNSV |
10.81
|
-7.88 |
-9.09 |
|
KPPSYPSPAQ |
13.39
|
-6.10 |
-7.31 |
|
LPPQPGSKKG |
14.07
|
-7.12 |
-8.33 |
| Q03790 |
FPSAPQPLFM |
12.48
|
-7.07 |
-8.28 |
|
PSAPQPLFME |
17.91
|
-3.08 |
-4.29 |
| P41809 |
YTSSPSVPVA |
16.53
|
-4.96 |
-6.17 |
|
SPSAPVAISS |
16.56
|
-3.92 |
-5.13 |
|
SPSAPVAVSS |
16.71
|
-3.37 |
-4.58 |
| Q05080 |
QKPDKPRPIV |
11.86
|
-7.95 |
-9.16 |
|
KPDKPRPIVG |
13.62
|
-7.41 |
-8.62 |
|
PDKPRPIVGE |
17.94
|
-4.41 |
-5.62 |
| P25344 |
NTPGPSPNEA |
18.48
|
-3.96 |
-5.17 |
| P53297 |
MPQMMPVMGS |
14.29
|
-8.17 |
-9.38 |
|
VPGMNPAMGM |
14.65
|
-5.08 |
-6.29 |
|
PEGKPPQKTS |
14.76
|
-5.67 |
-6.88 |
| P22147 |
HPHQMPYPNM |
12.09
|
-8.35 |
-9.56 |
|
FPPPPPMTNV |
12.45
|
-10.74 |
-11.95 |
|
IPTPPHPMNV |
12.52
|
-8.19 |
-9.40 |
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