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Matrix information:
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ADAN-name: SHO1_1QKX-27.PDB
Scoring matrix: SHO1_1QKX-27_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 13.57
Foldx random average score for Saccharomyces cerevisiae: 16.262 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5078
Total fragments: 1403515
Proteins after disorder filtering: 3270
Total fragments: 112741
Proteins after pattern filtering: 1609
Total fragments: 12219
Proteins after MINT filtering: 24
Total fragments: 426 ROC parameters:
TPR= 0.429
FPR= 0.316
ACC= 0.682
SPC= 0.684
MCC= 0.025 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AGAAAAAAA |
13.57
|
-5.56 |
0.00 |
| Best peptides |
YGEERDMWP |
0.00
|
-3.36 |
2.20 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
SKPLPLTPN |
13.94
|
-5.63 |
-0.07 |
|
KPLPLTPNS |
16.11
|
-4.52 |
1.04 |
| Q06604 |
LPTRPNKAE |
7.69
|
-10.23 |
-4.67 |
|
FEKGPRMPS |
8.11
|
-9.61 |
-4.05 |
|
KGPRMPSRG |
8.19
|
-8.42 |
-2.86 |
| P24583 |
RANAPLPPQ |
7.62
|
-9.65 |
-4.09 |
|
NAPLPPQPR |
12.17
|
-5.41 |
0.15 |
|
LPPQPRKHD |
12.93
|
-8.46 |
-2.90 |
| Q06412 |
VKERRPPPP |
4.42
|
-10.07 |
-4.51 |
|
KERRPPPPP |
6.45
|
-8.62 |
-3.06 |
|
FFTKPPPPL |
6.77
|
-8.51 |
-2.95 |
| P40036 |
PPLSPKSTV |
12.74
|
-6.89 |
-1.33 |
|
KIELPPLSP |
12.90
|
-7.88 |
-2.32 |
|
LPPLSPKST |
14.16
|
-7.36 |
-1.80 |
| P09620 |
EVPDPSNIP |
9.17
|
-7.67 |
-2.11 |
|
NPISKPSIH |
9.88
|
-6.67 |
-1.11 |
|
KLSNPISKP |
10.11
|
-9.32 |
-3.76 |
| P13186 |
PLPEREPPT |
7.15
|
-5.08 |
0.48 |
|
LPEREPPTY |
7.57
|
-6.24 |
-0.68 |
|
IPMSPNYGN |
9.69
|
-8.04 |
-2.48 |
| P32334 |
DFSSPSSPT |
11.72
|
-5.22 |
0.34 |
|
ADFSSPSSP |
12.87
|
-4.35 |
1.21 |
|
SPSSPTTTD |
13.30
|
-5.29 |
0.27 |
| P39083 |
LLQSPATPS |
8.73
|
-7.02 |
-1.46 |
|
QSPATPSNV |
13.91
|
-4.85 |
0.71 |
| P38753 |
YPSNLPIQH |
8.91
|
-9.19 |
-3.63 |
|
AHISPPVPG |
9.60
|
-8.63 |
-3.07 |
|
YSPYPSNLP |
10.19
|
-10.39 |
-4.83 |
| Q08229 |
NDYNPTIPP |
9.70
|
-9.14 |
-3.58 |
|
PLPSTPNED |
13.25
|
-5.51 |
0.05 |
|
TRPLPSTPN |
13.47
|
-6.90 |
-1.34 |
| Q00246 |
LPESPGTLD |
7.03
|
-8.49 |
-2.93 |
|
NLPRLPTPF |
9.03
|
-5.61 |
-0.05 |
|
LPRLPTPFA |
11.54
|
-7.93 |
-2.37 |
| P32448 |
VPTDSPQLP |
9.76
|
-7.55 |
-1.99 |
|
PTDSPQLPS |
11.64
|
-9.78 |
-4.22 |
|
SPQLPSKDK |
15.62
|
-6.47 |
-0.91 |
| Q04439 |
KKPAPPPPG |
6.69
|
-11.33 |
-5.77 |
|
KPKEPMFEA |
7.59
|
-6.10 |
-0.54 |
|
SNARPSPPT |
7.80
|
-7.50 |
-1.94 |
| P35197 |
SRPDHLPPS |
9.31
|
-7.88 |
-2.32 |
|
RPDHLPPSQ |
9.88
|
-9.32 |
-3.76 |
|
STPAKPPQE |
10.96
|
-6.23 |
-0.67 |
| Q12446 |
RNNRPVPPP |
5.47
|
-8.44 |
-2.88 |
|
RGPAPPPPP |
6.49
|
-10.08 |
-4.52 |
|
RLPAPPPPP |
6.98
|
-10.42 |
-4.86 |
| P08018 |
HPTRPNVAP |
8.73
|
-8.79 |
-3.23 |
|
RAPRRPLST |
9.94
|
-9.24 |
-3.68 |
|
STQHPTRPN |
11.06
|
-5.56 |
0.00 |
| P39969 |
VSPRRAPKP |
7.16
|
-9.48 |
-3.92 |
|
KPPSYPSPA |
8.53
|
-7.19 |
-1.63 |
|
SYPSPAQPP |
8.81
|
-7.14 |
-1.58 |
| Q03790 |
FPSAPQPLF |
8.04
|
-10.52 |
-4.96 |
|
KPTATPSPF |
9.99
|
-6.17 |
-0.61 |
|
GFPSAPQPL |
10.67
|
-5.31 |
0.25 |
| P41809 |
YTSSPSVPV |
7.57
|
-8.55 |
-2.99 |
|
YTSSPSAPA |
7.73
|
-7.97 |
-2.41 |
|
YTSSPSAPV |
7.86
|
-8.67 |
-3.11 |
| Q05080 |
QKPDKPRPI |
7.67
|
-7.68 |
-2.12 |
|
KPDKPRPIV |
9.03
|
-7.00 |
-1.44 |
|
LRQKPDKPR |
9.54
|
-9.18 |
-3.62 |
| P25344 |
NTPGPSPNE |
12.33
|
-5.46 |
0.10 |
| P53297 |
MFYHPSMPQ |
7.50
|
-10.70 |
-5.14 |
|
YHPSMPQMM |
7.95
|
-9.92 |
-4.36 |
|
APEGKPPQK |
9.43
|
-7.29 |
-1.73 |
| P22147 |
QPISFPPPP |
8.58
|
-8.50 |
-2.94 |
|
HPLHPHQMP |
8.86
|
-8.60 |
-3.04 |
|
NGLHPLHPH |
8.97
|
-7.33 |
-1.77 |
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