|
Matrix information:
(Help)
ADAN-name: SHO1_1QKX-26.PDB
Scoring matrix: SHO1_1QKX-26_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 21.09
Foldx random average score for Saccharomyces cerevisiae: 17.793 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5077
Total fragments: 852454
Proteins after disorder filtering: 3138
Total fragments: 59880
Proteins after pattern filtering: 1598
Total fragments: 13516
Proteins after MINT filtering: 24
Total fragments: 428 ROC parameters:
TPR= 0.429
FPR= 0.313
ACC= 0.684
SPC= 0.687
MCC= 0.026 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
21.09
|
1.15 |
0.00 |
| Best peptides |
DEGPRRFEK |
0.00
|
0.61 |
-0.54 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLPLTPNSK |
13.96
|
-8.41 |
-9.56 |
|
KPLPLTPNS |
14.51
|
-4.28 |
-5.43 |
| Q06604 |
PLLPTRPNK |
6.78
|
-6.88 |
-8.03 |
|
PPLPTRRDH |
8.03
|
-8.38 |
-9.53 |
|
PTPPSPPAK |
9.51
|
-6.92 |
-8.07 |
| P24583 |
PPQPRKHDK |
7.22
|
-7.92 |
-9.07 |
|
APLPPQPRK |
11.09
|
-5.65 |
-6.80 |
|
PLPPQPRKH |
11.40
|
-7.27 |
-8.42 |
| Q06412 |
RRPPPPPPL |
10.39
|
-7.33 |
-8.48 |
|
RPPPPPPLL |
11.59
|
-7.45 |
-8.60 |
|
TKPPPPLST |
12.28
|
-5.17 |
-6.32 |
| P40036 |
IELPPLSPK |
11.38
|
-4.61 |
-5.76 |
|
ELPPLSPKS |
13.41
|
-5.65 |
-6.80 |
|
KSLPTTPGI |
13.88
|
-4.19 |
-5.34 |
| P09620 |
SNPISKPSI |
12.96
|
-6.89 |
-8.04 |
|
EVPDPSNIP |
14.75
|
-4.51 |
-5.66 |
|
DPSNIPQMH |
14.85
|
-3.30 |
-4.45 |
| P13186 |
EPLPEREPP |
9.52
|
-6.96 |
-8.11 |
|
SSIPMSPNY |
14.04
|
-1.69 |
-2.84 |
|
PPIPAALPP |
14.11
|
-5.48 |
-6.63 |
| P32334 |
FSSPSSPTT |
14.57
|
-2.54 |
-3.69 |
|
PSSPTTTDI |
17.30
|
-1.90 |
-3.05 |
| P39083 |
LQSPATPSN |
14.99
|
-2.79 |
-3.94 |
| P38753 |
NNTPVMPPQ |
13.69
|
-4.04 |
-5.19 |
|
HISPPVPGP |
14.11
|
-3.85 |
-5.00 |
|
ISPPVPGPA |
14.96
|
-4.10 |
-5.25 |
| Q08229 |
PVQPGGHYK |
12.60
|
-5.66 |
-6.81 |
|
PTIPPRSKD |
14.30
|
-5.34 |
-6.49 |
|
RPLPSTPNE |
15.40
|
-3.37 |
-4.52 |
| Q00246 |
KNLPRLPTP |
12.74
|
-6.15 |
-7.30 |
|
EKNLPRLPT |
13.52
|
-7.28 |
-8.43 |
|
NLPRLPTPF |
14.98
|
-3.45 |
-4.60 |
| P32448 |
TDSPQLPSK |
8.79
|
-4.94 |
-6.09 |
|
PQLPSKDKS |
14.85
|
-4.14 |
-5.29 |
|
SPQLPSKDK |
15.97
|
-3.39 |
-4.54 |
| Q04439 |
PPPPGMQNK |
10.00
|
-5.75 |
-6.90 |
|
PPPPSSKPK |
10.40
|
-5.11 |
-6.26 |
|
IPPPPPPPP |
11.08
|
-8.05 |
-9.20 |
| P35197 |
GSTPAKPPQ |
11.99
|
-4.37 |
-5.52 |
|
SRPDHLPPS |
13.60
|
-6.45 |
-7.60 |
|
RPDHLPPSQ |
14.96
|
-4.92 |
-6.07 |
| Q12446 |
PPPPPRRGP |
9.67
|
-7.10 |
-8.25 |
|
PPPPHRHVT |
9.80
|
-7.11 |
-8.26 |
|
GPAPPPPPH |
9.94
|
-7.74 |
-8.89 |
| P08018 |
DGPPPRLPS |
7.37
|
-9.72 |
-10.87 |
|
TQHPTRPNV |
9.65
|
-4.16 |
-5.31 |
|
TRPNVAPHK |
12.82
|
-4.80 |
-5.95 |
| P39969 |
YPSPAQPPK |
10.22
|
-4.65 |
-5.80 |
|
RRAPKPPSY |
11.52
|
-5.37 |
-6.52 |
|
LLPPQPGSK |
12.17
|
-4.51 |
-5.66 |
| Q03790 |
TATPSPFRP |
13.51
|
-3.60 |
-4.75 |
|
FPSAPQPLF |
14.50
|
-3.41 |
-4.56 |
|
DGKPTATPS |
15.02
|
-4.27 |
-5.42 |
| P41809 |
TPYPSPNSY |
13.17
|
-5.24 |
-6.39 |
|
TSSPSAPAA |
14.10
|
-3.64 |
-4.79 |
|
TSSPSAPVA |
14.26
|
-3.13 |
-4.28 |
| Q05080 |
RQKPDKPRP |
9.52
|
-7.19 |
-8.34 |
|
KPDKPRPIV |
11.64
|
-5.89 |
-7.04 |
|
QKPDKPRPI |
14.83
|
-5.13 |
-6.28 |
| P25344 |
TPGPSPNEA |
10.68
|
-6.72 |
-7.87 |
| P53297 |
SLPPKPISK |
11.36
|
-6.67 |
-7.82 |
|
SSLPPKPIS |
11.92
|
-5.77 |
-6.92 |
|
PSMPQMMPV |
12.01
|
-5.51 |
-6.66 |
| P22147 |
IPPPAPHGF |
10.61
|
-6.99 |
-8.14 |
|
DEIPKGEPF |
11.24
|
-4.93 |
-6.08 |
|
MSIPPPAPH |
11.34
|
-4.94 |
-6.09 |
|
