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Matrix information:
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ADAN-name: SHO1_1QKX-23.PDB
Scoring matrix: SHO1_1QKX-23_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 11.15
Foldx random average score for Saccharomyces cerevisiae: 11.907 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2186557
Proteins after random average filtering: 5078
Total fragments: 1209836
Proteins after disorder filtering: 3418
Total fragments: 90100
Proteins after pattern filtering: 1522
Total fragments: 6649
Proteins after MINT filtering: 23
Total fragments: 196 ROC parameters:
TPR= 0.411
FPR= 0.298
ACC= 0.698
SPC= 0.702
MCC= 0.026 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
11.15
|
-0.72 |
0.00 |
| Best peptides |
GKIRPWM |
0.00
|
0.88 |
1.60 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q06604 |
GPRMPSR |
4.08
|
-2.28 |
-1.56 |
|
LPTRPNK |
6.76
|
-1.89 |
-1.17 |
|
KGPRMPS |
6.95
|
-2.25 |
-1.53 |
| P24583 |
LPPQPRK |
6.35
|
-3.24 |
-2.52 |
| Q06412 |
NSPKSPR |
7.68
|
-2.40 |
-1.68 |
|
FSPNSPK |
9.60
|
-2.27 |
-1.55 |
|
SPKSPRD |
9.67
|
-0.14 |
0.58 |
| P40036 |
PPLSPKS |
10.00
|
-1.27 |
-0.55 |
| P09620 |
PISKPSI |
7.42
|
-1.50 |
-0.78 |
|
NPISKPS |
9.65
|
-0.63 |
0.09 |
|
PDPSNIP |
9.69
|
-2.04 |
-1.32 |
| P13186 |
LPEREPP |
5.87
|
-3.74 |
-3.02 |
|
IPAALPP |
7.63
|
-3.58 |
-2.86 |
|
IPMSPNY |
8.31
|
-1.76 |
-1.04 |
| P32334 |
SSPSSPT |
11.40
|
-0.95 |
-0.23 |
|
SPSSPTT |
11.46
|
-0.08 |
0.64 |
| P39083 |
QSPATPS |
10.31
|
-2.49 |
-1.77 |
| P38753 |
LPIQHPT |
7.18
|
-1.78 |
-1.06 |
|
TPVMPPQ |
8.88
|
-2.28 |
-1.56 |
|
YPSNLPI |
9.71
|
-0.44 |
0.28 |
| Q08229 |
PLPSTPN |
11.03
|
-1.26 |
-0.54 |
|
TPVQPGG |
11.34
|
0.28 |
1.00 |
| Q00246 |
NLPRLPT |
7.71
|
-1.75 |
-1.03 |
|
LPESPGT |
10.06
|
-2.21 |
-1.49 |
| P32448 |
DSPQLPS |
10.35
|
-0.80 |
-0.08 |
|
PTDSPQL |
10.87
|
-2.78 |
-2.06 |
|
RVPTDSP |
11.87
|
-1.59 |
-0.87 |
| Q04439 |
SKPKEPM |
6.12
|
-2.55 |
-1.83 |
|
KKPAPPP |
6.95
|
-4.04 |
-3.32 |
|
GSPSELP |
7.01
|
-2.90 |
-2.18 |
| P35197 |
TPAKPPQ |
6.52
|
-2.46 |
-1.74 |
|
RPDHLPP |
7.33
|
-1.58 |
-0.86 |
|
STPAKPP |
9.65
|
-2.97 |
-2.25 |
| Q12446 |
GAPAPPP |
6.38
|
-3.70 |
-2.98 |
|
PPPRRGP |
6.54
|
-3.06 |
-2.34 |
|
GQPAVPL |
6.68
|
-2.98 |
-2.26 |
| P08018 |
RAPRRPL |
4.64
|
-3.46 |
-2.74 |
|
APRRPLS |
6.34
|
-1.01 |
-0.29 |
|
HPTRPNV |
6.81
|
-0.91 |
-0.19 |
| P39969 |
SPRRAPK |
6.26
|
-1.91 |
-1.19 |
|
QPPKSPL |
6.43
|
-3.12 |
-2.40 |
|
VSPRRAP |
6.43
|
-1.28 |
-0.56 |
| Q03790 |
GFPSAPQ |
7.81
|
-1.92 |
-1.20 |
|
FPSAPQP |
8.65
|
-3.44 |
-2.72 |
|
KPTATPS |
10.12
|
-1.96 |
-1.24 |
| P41809 |
SPSAPAA |
10.51
|
-1.44 |
-0.72 |
|
SPSAPVA |
10.92
|
-1.11 |
-0.39 |
|
PYPSPNS |
11.30
|
-1.61 |
-0.89 |
| Q05080 |
KPDKPRP |
5.45
|
-3.50 |
-2.78 |
|
QKPDKPR |
10.01
|
0.16 |
0.88 |
| P25344 |
PGPSPNE |
11.13
|
-1.04 |
-0.32 |
|
NTPGPSP |
11.75
|
-1.53 |
-0.81 |
| P53297 |
HPSMPQM |
5.55
|
-2.31 |
-1.59 |
|
GFPMGGP |
6.06
|
-2.81 |
-2.09 |
|
LPPKPIS |
6.80
|
-2.84 |
-2.12 |
| P22147 |
HPLHPHQ |
5.36
|
-1.63 |
-0.91 |
|
LHPHQMP |
6.94
|
-1.30 |
-0.58 |
|
TPPHPMN |
7.07
|
-1.64 |
-0.92 |
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