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Matrix information:
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ADAN-name: SHO1_1QKX-22.PDB
Scoring matrix: SHO1_1QKX-22_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 16.45
Foldx random average score for Saccharomyces cerevisiae: 14.763 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2186557
Proteins after random average filtering: 5078
Total fragments: 979197
Proteins after disorder filtering: 3357
Total fragments: 59261
Proteins after pattern filtering: 1272
Total fragments: 3892
Proteins after MINT filtering: 20
Total fragments: 90 ROC parameters:
TPR= 0.357
FPR= 0.249
ACC= 0.746
SPC= 0.751
MCC= 0.026 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
16.45
|
0.37 |
0.00 |
| Best peptides |
MRDRPKP |
0.00
|
4.45 |
4.08 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLPLTPN |
14.40
|
-2.37 |
-2.74 |
| Q06604 |
PRMPSRG |
13.23
|
-2.91 |
-3.28 |
|
RVKPAPP |
13.24
|
-0.90 |
-1.27 |
|
KPLLPTR |
13.56
|
-2.85 |
-3.22 |
| P24583 |
ANAPLPP |
13.59
|
-0.71 |
-1.08 |
| P13186 |
IPAALPP |
11.59
|
-3.45 |
-3.82 |
|
LPEREPP |
11.82
|
-3.11 |
-3.48 |
|
PAALPPS |
12.90
|
-1.75 |
-2.12 |
| P22147 |
PHQMPYP |
9.95
|
-3.37 |
-3.74 |
|
IPKGEPF |
10.66
|
-3.24 |
-3.61 |
|
PISFPPP |
10.93
|
-1.83 |
-2.20 |
| Q05080 |
KPDKPRP |
10.91
|
-3.08 |
-3.45 |
|
RQKPDKP |
12.11
|
0.18 |
-0.19 |
| Q08229 |
TPVQPGG |
14.18
|
-2.21 |
-2.58 |
| P40036 |
PPLSPKS |
11.82
|
-1.71 |
-2.08 |
| Q00246 |
PRLPTPF |
11.41
|
-2.36 |
-2.73 |
|
NLPRLPT |
14.48
|
-1.15 |
-1.52 |
| P53297 |
MPFQPQP |
10.81
|
-2.44 |
-2.81 |
|
MPQMMPV |
11.64
|
-1.54 |
-1.91 |
|
PQMMPVM |
12.26
|
-3.64 |
-4.01 |
| Q04439 |
KPKEPMF |
11.95
|
-1.26 |
-1.63 |
|
ANIPPPP |
11.96
|
-1.49 |
-1.86 |
|
PSSKPKE |
12.38
|
-1.87 |
-2.24 |
| P32448 |
PTDSPQL |
12.98
|
-2.09 |
-2.46 |
|
VPTDSPQ |
13.24
|
-0.67 |
-1.04 |
|
PRVPTDS |
14.45
|
-2.13 |
-2.50 |
| P35197 |
RPDHLPP |
6.96
|
-0.83 |
-1.20 |
|
TPAKPPQ |
12.26
|
-2.20 |
-2.57 |
| Q12446 |
PRRGPAP |
9.23
|
-2.76 |
-3.13 |
|
PPRRGPA |
10.72
|
-2.25 |
-2.62 |
|
VPVAPPP |
11.15
|
-3.31 |
-3.68 |
| P08018 |
PNVAPHK |
10.62
|
-2.71 |
-3.08 |
|
APRRPLS |
13.27
|
-1.64 |
-2.01 |
|
TRPNVAP |
13.87
|
-3.64 |
-4.01 |
| P39969 |
PRRAPKP |
5.67
|
-2.45 |
-2.82 |
|
RRAPKPP |
10.96
|
-0.92 |
-1.29 |
|
SPRRAPK |
12.12
|
-2.15 |
-2.52 |
| P09620 |
PISKPSI |
13.62
|
-0.58 |
-0.95 |
|
NPISKPS |
14.65
|
-0.52 |
-0.89 |
| Q03790 |
KPTATPS |
14.44
|
-2.11 |
-2.48 |
| Q06412 |
ERRPPPP |
10.78
|
-2.91 |
-3.28 |
|
PMVSPSS |
12.92
|
-1.78 |
-2.15 |
|
RRPPPPP |
14.16
|
-3.39 |
-3.76 |
| P38753 |
TPVMPPQ |
11.01
|
-2.54 |
-2.91 |
|
PIQHPTN |
12.62
|
-0.44 |
-0.81 |
|
NNTPVMP |
13.79
|
-0.16 |
-0.53 |
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