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Matrix information:
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ADAN-name: SHO1_1QKX-21.PDB
Scoring matrix: SHO1_1QKX-21_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 18.83
Foldx random average score for Saccharomyces cerevisiae: 17.908 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2171323
Proteins after random average filtering: 5078
Total fragments: 1259938
Proteins after disorder filtering: 3063
Total fragments: 59136
Proteins after pattern filtering: 1193
Total fragments: 3131
Proteins after MINT filtering: 21
Total fragments: 101 ROC parameters:
TPR= 0.375
FPR= 0.233
ACC= 0.762
SPC= 0.767
MCC= 0.035 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAGGAAAA |
18.83
|
2.19 |
0.00 |
| Best peptides |
RWWMGIPRRR |
0.00
|
7.91 |
5.72 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPNSK |
14.60
|
-1.89 |
-4.08 |
|
PLPLTPNSKY |
17.82
|
-1.59 |
-3.78 |
| Q06604 |
PLLPTRPNKA |
12.73
|
0.33 |
-1.86 |
|
EKGPRMPSRG |
13.16
|
-3.06 |
-5.25 |
|
RVKPAPPVSR |
14.20
|
-3.62 |
-5.81 |
| P24583 |
APLPPQPRKH |
15.73
|
-3.85 |
-6.04 |
|
PPQPRKHDKT |
17.32
|
-1.69 |
-3.88 |
|
PLPPQPRKHD |
17.63
|
-1.58 |
-3.77 |
| P13186 |
PLTPLATNTH |
12.40
|
-2.44 |
-4.63 |
|
PMSPNYGNQS |
12.44
|
0.25 |
-1.94 |
|
SSIPMSPNYG |
15.21
|
-1.89 |
-4.08 |
| P41809 |
PQTPLRSLAG |
17.26
|
-1.60 |
-3.79 |
| Q06412 |
PNSPKSPRDS |
14.11
|
0.39 |
-1.80 |
|
PPPPLSTSRN |
15.78
|
-2.05 |
-4.24 |
|
SPMVSPSSQS |
16.30
|
-1.58 |
-3.77 |
| Q08229 |
RPLPSTPNED |
15.77
|
0.32 |
-1.87 |
|
LPTPVQPGGH |
16.32
|
-2.65 |
-4.84 |
|
PSTPNEDSRV |
16.92
|
-1.58 |
-3.77 |
| P32334 |
FSSPSSPTTT |
13.69
|
1.50 |
-0.69 |
| Q00246 |
SNLPESPGTL |
17.47
|
0.72 |
-1.47 |
| P40036 |
ELPPLSPKST |
14.11
|
-1.24 |
-3.43 |
|
KSLPTTPGIR |
16.60
|
-2.54 |
-4.73 |
|
SLPTTPGIRS |
16.97
|
-2.29 |
-4.48 |
| P22147 |
PHQMPYPNMN |
12.91
|
-4.04 |
-6.23 |
|
EIPKGEPFDS |
14.84
|
0.62 |
-1.57 |
|
GLHPLHPHQM |
16.21
|
-1.60 |
-3.79 |
| P35197 |
RPDHLPPSQG |
16.96
|
-1.81 |
-4.00 |
|
STPAKPPQER |
17.34
|
-1.62 |
-3.81 |
| Q04439 |
NNIPTPPQNR |
13.30
|
-2.29 |
-4.48 |
|
PPPPGMQNKA |
14.24
|
-0.47 |
-2.66 |
|
SSKPKEPMFE |
15.34
|
-1.28 |
-3.47 |
| Q12446 |
RPLPQLPNRN |
9.86
|
-4.27 |
-6.46 |
|
PLPQLPNRNN |
14.95
|
-2.44 |
-4.63 |
|
ALPPASPEVR |
15.27
|
-1.09 |
-3.28 |
| P53297 |
GFPMGGPSAS |
13.00
|
-3.01 |
-5.20 |
|
FYHPSMPQMM |
13.23
|
-2.24 |
-4.43 |
|
SMPQMMPVMG |
13.62
|
-2.72 |
-4.91 |
| P39969 |
PKSPLLNNTR |
11.70
|
-3.18 |
-5.37 |
|
SPIPSPTRNS |
13.85
|
-0.99 |
-3.18 |
|
AQPPKSPLLN |
14.97
|
-3.02 |
-5.21 |
| P09620 |
PDPSNIPQMH |
13.64
|
-4.51 |
-6.70 |
|
SNPISKPSIH |
16.97
|
-1.71 |
-3.90 |
| P32448 |
PQLPSKDKSQ |
15.12
|
-0.48 |
-2.67 |
|
TDSPQLPSKD |
17.48
|
0.45 |
-1.74 |
| P39083 |
PATPSNVSMY |
16.75
|
-1.41 |
-3.60 |
|
QSPATPSNVS |
17.48
|
1.85 |
-0.34 |
| P38753 |
NLPIQHPTNS |
11.77
|
-2.60 |
-4.79 |
|
LPIQHPTNSA |
15.03
|
1.79 |
-0.40 |
|
NTPVMPPQRQ |
15.77
|
-2.93 |
-5.12 |
| P08018 |
TQHPTRPNVA |
14.96
|
0.30 |
-1.89 |
|
PPRLPSDKFS |
16.06
|
-1.92 |
-4.11 |
|
