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Matrix information:
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ADAN-name: SHO1_1QKX-19.PDB
Scoring matrix: SHO1_1QKX-19_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 19.4
Foldx random average score for Saccharomyces cerevisiae: 22.314 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5078
Total fragments: 1044900
Proteins after disorder filtering: 3148
Total fragments: 61462
Proteins after pattern filtering: 1318
Total fragments: 4460
Proteins after MINT filtering: 21
Total fragments: 130 ROC parameters:
TPR= 0.375
FPR= 0.258
ACC= 0.738
SPC= 0.742
MCC= 0.028 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
19.40
|
4.62 |
0.00 |
| Best peptides |
RDRRIGRGR |
0.00
|
4.01 |
-0.61 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLTPNSKYN |
18.35
|
-0.09 |
-4.71 |
|
KPLPLTPNS |
22.04
|
-0.62 |
-5.24 |
| Q06604 |
GPRMPSRGR |
13.52
|
-3.88 |
-8.50 |
|
PLLPTRPNK |
16.52
|
-4.12 |
-8.74 |
|
EEKPLLPTR |
16.63
|
-4.76 |
-9.38 |
| P24583 |
APLPPQPRK |
19.61
|
-1.87 |
-6.49 |
|
RANAPLPPQ |
19.87
|
-4.10 |
-8.72 |
|
PPQPRKHDK |
21.73
|
0.66 |
-3.96 |
| P13186 |
PMSPNYGNQ |
18.25
|
-2.00 |
-6.62 |
|
KAPSYVPNR |
18.76
|
-3.13 |
-7.75 |
|
NSSIPMSPN |
19.19
|
-1.39 |
-6.01 |
| P22147 |
NGLHPLHPH |
16.08
|
0.87 |
-3.75 |
|
PHQMPYPNM |
16.55
|
-3.25 |
-7.87 |
|
NLNIPTPPH |
18.03
|
0.83 |
-3.79 |
| Q05080 |
LRQKPDKPR |
10.28
|
-6.19 |
-10.81 |
| P38753 |
PVMPPQRQS |
18.31
|
-2.70 |
-7.32 |
|
PIQHPTNSA |
19.04
|
-3.48 |
-8.10 |
|
NNTPVMPPQ |
19.25
|
-1.91 |
-6.53 |
| Q08229 |
PVQPGGHYK |
15.91
|
-2.03 |
-6.65 |
|
PSTPNEDSR |
20.15
|
-2.32 |
-6.94 |
|
LPTPVQPGG |
21.37
|
-0.24 |
-4.86 |
| P40036 |
IELPPLSPK |
16.15
|
-3.85 |
-8.47 |
|
ELPPLSPKS |
20.86
|
-0.69 |
-5.31 |
|
PTTPGIRSG |
21.03
|
-1.32 |
-5.94 |
| Q00246 |
SNLPESPGT |
21.46
|
-0.24 |
-4.86 |
| P53297 |
PGGIPFQGM |
13.48
|
-3.03 |
-7.65 |
|
PGMNPAMGM |
14.93
|
-3.25 |
-7.87 |
|
FYHPSMPQM |
17.39
|
-3.13 |
-7.75 |
| Q04439 |
PSSKPKEPM |
15.40
|
-2.43 |
-7.05 |
|
NNNIPTPPQ |
18.19
|
-1.10 |
-5.72 |
|
PKEPMFEAA |
18.85
|
-2.09 |
-6.71 |
| P32448 |
TDSPQLPSK |
18.56
|
-2.73 |
-7.35 |
|
PRVPTDSPQ |
20.29
|
-1.81 |
-6.43 |
|
PQLPSKDKS |
21.38
|
0.95 |
-3.67 |
| P35197 |
PAKPPQERS |
20.62
|
-1.74 |
-6.36 |
|
GSTPAKPPQ |
21.93
|
-0.06 |
-4.68 |
| Q12446 |
PQLPNRNNR |
15.00
|
-2.23 |
-6.85 |
|
RPLPQLPNR |
18.15
|
-2.27 |
-6.89 |
|
PASPEVRKE |
19.20
|
-2.33 |
-6.95 |
| P08018 |
PRLPSDKFS |
16.81
|
-1.25 |
-5.87 |
|
PRRPLSTQH |
18.21
|
0.69 |
-3.93 |
|
TRPNVAPHK |
18.48
|
-2.26 |
-6.88 |
| P39969 |
KLLPPQPGS |
16.50
|
-2.55 |
-7.17 |
|
LPPQPGSKK |
18.08
|
-1.42 |
-6.04 |
|
LSPIPSPTR |
19.22
|
-1.28 |
-5.90 |
| P09620 |
PSNIPQMHA |
18.70
|
-1.76 |
-6.38 |
|
PDPSNIPQM |
19.20
|
-0.89 |
-5.51 |
|
LSNPISKPS |
20.39
|
-1.45 |
-6.07 |
| Q03790 |
PTATPSPFR |
19.26
|
-2.00 |
-6.62 |
|
LNGFPSAPQ |
21.79
|
-1.54 |
-6.16 |
| P39083 |
PATPSNVSM |
19.21
|
-1.98 |
-6.60 |
| Q06412 |
PKLPPLNTR |
16.51
|
-1.18 |
-5.80 |
|
PKSPRDSSK |
17.85
|
-1.60 |
-6.22 |
|
NGFSPNSPK |
17.86
|
-1.27 |
-5.89 |
|
