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Matrix information:
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ADAN-name: SHO1_1QKX-15.PDB
Scoring matrix: SHO1_1QKX-15_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.39
Foldx random average score for Saccharomyces cerevisiae: 14.256 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5078
Total fragments: 912653
Proteins after disorder filtering: 3121
Total fragments: 50230
Proteins after pattern filtering: 1424
Total fragments: 6014
Proteins after MINT filtering: 21
Total fragments: 183 ROC parameters:
TPR= 0.375
FPR= 0.279
ACC= 0.717
SPC= 0.721
MCC= 0.022 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
16.39
|
12.32 |
0.00 |
| Best peptides |
TGWHIRENA |
0.00
|
7.08 |
-5.24 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNSKY |
13.90
|
-1.43 |
-13.75 |
|
KPLPLTPNS |
14.07
|
2.22 |
-10.10 |
| Q06604 |
KGPRMPSRG |
9.60
|
0.32 |
-12.00 |
|
PLLPTRPNK |
10.34
|
1.52 |
-10.80 |
|
PRMPSRGRP |
10.37
|
0.57 |
-11.75 |
| P24583 |
LPPQPRKHD |
8.20
|
-0.20 |
-12.52 |
|
APLPPQPRK |
11.56
|
-0.28 |
-12.60 |
|
PPQPRKHDK |
13.54
|
0.59 |
-11.73 |
| P13186 |
IPLTPLATN |
12.69
|
1.42 |
-10.90 |
|
LPEREPPTY |
12.94
|
-1.38 |
-13.70 |
|
APSYVPNRV |
12.98
|
1.18 |
-11.14 |
| P41809 |
TSSPSVPVA |
13.51
|
3.54 |
-8.78 |
|
TTPYPSPNS |
13.95
|
3.01 |
-9.31 |
| Q08229 |
PTIPPRSKD |
11.64
|
1.31 |
-11.01 |
|
LPTPVQPGG |
11.88
|
0.97 |
-11.35 |
|
TPVQPGGHY |
12.93
|
1.58 |
-10.74 |
| Q05080 |
KPDKPRPIV |
10.09
|
-1.88 |
-14.20 |
|
RQKPDKPRP |
13.18
|
-1.71 |
-14.03 |
| P25344 |
TPGPSPNEA |
12.19
|
2.80 |
-9.52 |
| Q00246 |
NLPRLPTPF |
13.67
|
0.34 |
-11.98 |
|
LPRLPTPFA |
14.14
|
-0.54 |
-12.86 |
|
EKNLPRLPT |
14.23
|
-0.16 |
-12.48 |
| P32448 |
TDSPQLPSK |
13.25
|
2.64 |
-9.68 |
| P53297 |
MPFQPQPMF |
8.17
|
-0.94 |
-13.26 |
|
HPSMPQMMP |
9.31
|
-2.93 |
-15.25 |
|
LPPKPISKT |
9.65
|
1.53 |
-10.79 |
| P22147 |
HPLHPHQMP |
9.56
|
-1.17 |
-13.49 |
|
NGLHPLHPH |
10.26
|
0.34 |
-11.98 |
|
GFGQPISFP |
10.36
|
0.01 |
-12.31 |
| P35197 |
RPDHLPPSQ |
10.69
|
0.51 |
-11.81 |
|
PAKPPQERS |
12.36
|
2.70 |
-9.62 |
|
TPAKPPQER |
12.89
|
0.62 |
-11.70 |
| Q12446 |
PFPFPIPEI |
8.13
|
-0.32 |
-12.64 |
|
APSQPQSNP |
8.23
|
0.35 |
-11.97 |
|
PFPVPQQQF |
8.68
|
-0.17 |
-12.49 |
| P08018 |
APRRPLSTQ |
10.25
|
0.65 |
-11.67 |
|
TQHPTRPNV |
11.28
|
0.81 |
-11.51 |
|
GPPPRLPSD |
11.65
|
3.22 |
-9.10 |
| P39969 |
PKSPLLNNT |
10.46
|
2.18 |
-10.14 |
|
PPKSPLLNN |
10.54
|
1.56 |
-10.76 |
|
QPPKSPLLN |
12.51
|
1.38 |
-10.94 |
| P09620 |
KLSNPISKP |
12.65
|
-0.43 |
-12.75 |
| Q03790 |
FPSAPQPLF |
10.09
|
-1.04 |
-13.36 |
| Q04439 |
PKEPMFEAA |
10.84
|
1.74 |
-10.58 |
|
IPTPPQNRD |
11.12
|
3.45 |
-8.87 |
|
KPKEPMFEA |
11.32
|
0.96 |
-11.36 |
| Q06412 |
PPPPLLYST |
10.70
|
0.66 |
-11.66 |
|
PPPPPLLYS |
12.13
|
0.21 |
-12.11 |
|
SPKSPRDSS |
13.19
|
1.74 |
-10.58 |
| P38753 |
PIQHPTNSA |
10.22
|
1.11 |
-11.21 |
|
TPVMPPQRQ |
10.61
|
-0.65 |
-12.97 |
|
PYPSNLPIQ |
11.95
|
1.23 |
-11.09 |
|
