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Matrix information:
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ADAN-name: SHO1_1QKX-14.PDB
Scoring matrix: SHO1_1QKX-14_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 16.07
Foldx random average score for Saccharomyces cerevisiae: 17.995 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5078
Total fragments: 1200819
Proteins after disorder filtering: 3205
Total fragments: 71888
Proteins after pattern filtering: 1532
Total fragments: 8769
Proteins after MINT filtering: 24
Total fragments: 305 ROC parameters:
TPR= 0.429
FPR= 0.3
ACC= 0.697
SPC= 0.7
MCC= 0.029 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
16.07
|
4.71 |
0.00 |
| Best peptides |
PWFMIRYLL |
0.00
|
2.93 |
-1.78 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLTPNSKYN |
14.80
|
0.61 |
-4.10 |
|
SKPLPLTPN |
16.69
|
-0.23 |
-4.94 |
| Q06604 |
PPLPTRRDH |
10.11
|
0.05 |
-4.66 |
|
GPRMPSRGR |
10.18
|
-3.55 |
-8.26 |
|
PAPPVSRST |
12.13
|
-1.54 |
-6.25 |
| P24583 |
PLPPQPRKH |
14.32
|
0.13 |
-4.58 |
|
LPPQPRKHD |
14.96
|
1.43 |
-3.28 |
|
NAPLPPQPR |
15.89
|
-1.35 |
-6.06 |
| Q06412 |
PPPPLLYST |
11.26
|
-3.88 |
-8.59 |
|
PPPPLSTSR |
12.45
|
-2.54 |
-7.25 |
|
PKLPPLNTR |
12.47
|
-2.44 |
-7.15 |
| P40036 |
PPLSPKSTV |
12.54
|
-1.87 |
-6.58 |
|
SLPTTPGIR |
14.15
|
-1.67 |
-6.38 |
|
LPPLSPKST |
15.39
|
-1.68 |
-6.39 |
| P09620 |
PSNIPQMHA |
12.64
|
-2.36 |
-7.07 |
|
DPSNIPQMH |
15.90
|
1.70 |
-3.01 |
|
PDPSNIPQM |
16.61
|
-2.10 |
-6.81 |
| P13186 |
PAALPPSDM |
12.70
|
-3.56 |
-8.27 |
|
APSYVPNRV |
13.33
|
-2.53 |
-7.24 |
|
QNNIPLTPL |
14.90
|
-2.00 |
-6.71 |
| P32334 |
DFSSPSSPT |
17.45
|
-0.39 |
-5.10 |
| P39083 |
PATPSNVSM |
13.94
|
-2.04 |
-6.75 |
|
SPATPSNVS |
15.75
|
-0.38 |
-5.09 |
| P38753 |
PIQHPTNSA |
12.86
|
-2.50 |
-7.21 |
|
NLPIQHPTN |
13.41
|
-2.43 |
-7.14 |
|
PVPGPALYA |
15.12
|
-1.78 |
-6.49 |
| Q08229 |
LPSTPNEDS |
14.59
|
-2.69 |
-7.40 |
|
PTIPPRSKD |
15.39
|
-1.33 |
-6.04 |
|
PTPVQPGGH |
15.56
|
1.49 |
-3.22 |
| Q00246 |
EKNLPRLPT |
12.23
|
-3.65 |
-8.36 |
|
LPRLPTPFA |
13.98
|
-3.19 |
-7.90 |
|
PESPGTLDE |
16.06
|
1.93 |
-2.78 |
| P32448 |
PQLPSKDKS |
12.60
|
0.05 |
-4.66 |
|
RVPTDSPQL |
15.76
|
-2.88 |
-7.59 |
| Q04439 |
PSSKPKEPM |
12.85
|
-4.69 |
-9.40 |
|
PKEPMFEAA |
12.89
|
-2.04 |
-6.75 |
|
PTPPQNRDV |
14.27
|
-2.52 |
-7.23 |
| P35197 |
PDHLPPSQG |
12.55
|
-2.25 |
-6.96 |
|
TPAKPPQER |
13.78
|
-1.73 |
-6.44 |
|
PAKPPQERS |
14.51
|
-0.50 |
-5.21 |
| Q12446 |
PPPPPRASR |
8.93
|
-4.60 |
-9.31 |
|
PPPPMRTTT |
9.64
|
-3.76 |
-8.47 |
|
PQLPNRNNR |
9.71
|
-3.10 |
-7.81 |
| P08018 |
DGPPPRLPS |
11.97
|
-3.32 |
-8.03 |
|
TQHPTRPNV |
12.93
|
-0.96 |
-5.67 |
|
PRRPLSTQH |
13.08
|
2.27 |
-2.44 |
| P39969 |
PAQPPKSPL |
11.38
|
-3.37 |
-8.08 |
|
PRRAPKPPS |
12.00
|
-1.22 |
-5.93 |
|
AQPPKSPLL |
12.01
|
-1.63 |
-6.34 |
| Q03790 |
PTATPSPFR |
12.89
|
-1.55 |
-6.26 |
|
GFPSAPQPL |
15.81
|
-2.69 |
-7.40 |
|
PSAPQPLFM |
16.56
|
-1.21 |
-5.92 |
| P41809 |
SPSVPVAVS |
15.75
|
-1.52 |
-6.23 |
|
PSAPVAISS |
16.53
|
1.28 |
-3.43 |
|
PSAPVAVSS |
16.77
|
1.35 |
-3.36 |
| Q05080 |
KPDKPRPIV |
9.49
|
-5.11 |
-9.82 |
|
PDKPRPIVG |
13.61
|
-0.11 |
-4.82 |
|
LRQKPDKPR |
16.03
|
-1.30 |
-6.01 |
| P25344 |
TPGPSPNEA |
16.79
|
0.58 |
-4.13 |
| P53297 |
PGGIPFQGM |
9.64
|
-3.84 |
-8.55 |
|
PQMMPVMGS |
10.79
|
-2.23 |
-6.94 |
|
PEGKPPQKT |
11.14
|
-1.86 |
-6.57 |
| P22147 |
PPPAPHGFG |
10.07
|
-3.09 |
-7.80 |
|
PPHPMNVVG |
11.53
|
-1.63 |
-6.34 |
|
PYNIPPGFM |
12.27
|
-5.75 |
-10.46 |
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