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Matrix information:
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ADAN-name: SHO1_1QKX-13.PDB
Scoring matrix: SHO1_1QKX-13_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 29.14
Foldx random average score for Saccharomyces cerevisiae: 24.057 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 916688
Proteins after disorder filtering: 3239
Total fragments: 59959
Proteins after pattern filtering: 1586
Total fragments: 10365
Proteins after MINT filtering: 24
Total fragments: 349 ROC parameters:
TPR= 0.429
FPR= 0.311
ACC= 0.686
SPC= 0.689
MCC= 0.026 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
29.14
|
3.81 |
0.00 |
| Best peptides |
RPKKNPRE |
0.00
|
-0.05 |
-3.86 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLTPNSKY |
18.38
|
-4.41 |
-8.22 |
|
SKPLPLTP |
21.02
|
-5.15 |
-8.96 |
|
LPLTPNSK |
21.76
|
-1.52 |
-5.34 |
| Q06604 |
KPLLPTRP |
11.96
|
-8.83 |
-12.65 |
|
PPPLPTRR |
13.85
|
-8.91 |
-12.73 |
|
GPRMPSRG |
14.21
|
-7.06 |
-10.88 |
| P24583 |
LPPQPRKH |
16.81
|
-4.43 |
-8.24 |
|
PLPPQPRK |
18.47
|
-6.67 |
-10.48 |
|
NAPLPPQP |
20.80
|
-5.42 |
-9.23 |
| Q06412 |
FFTKPPPP |
17.01
|
-6.04 |
-9.86 |
|
RPPPPPPL |
17.97
|
-5.19 |
-9.01 |
|
NSPKSPRD |
17.98
|
-3.04 |
-6.86 |
| P40036 |
LPTTPGIR |
18.49
|
-5.72 |
-9.54 |
|
LPPLSPKS |
18.80
|
-5.18 |
-8.99 |
|
SKSLPTTP |
21.74
|
-4.90 |
-8.71 |
| P09620 |
PISKPSIH |
21.59
|
-4.98 |
-8.79 |
|
DPSNIPQM |
22.50
|
-2.25 |
-6.06 |
|
VPDPSNIP |
22.66
|
-3.44 |
-7.25 |
| P13186 |
LPEREPPT |
17.02
|
-5.33 |
-9.14 |
|
RPPIPAAL |
17.86
|
-6.66 |
-10.48 |
|
SYVPNRVP |
19.79
|
-3.24 |
-7.05 |
| P32334 |
SPSSPTTT |
22.49
|
-0.99 |
-4.80 |
| P39083 |
SPATPSNV |
23.22
|
-1.87 |
-5.69 |
|
LLQSPATP |
23.27
|
-2.99 |
-6.80 |
| P38753 |
TPVMPPQR |
18.14
|
-3.48 |
-7.29 |
|
YPSNLPIQ |
19.08
|
-6.08 |
-9.89 |
|
PVMPPQRQ |
19.26
|
-5.87 |
-9.69 |
| Q08229 |
NPTIPPRS |
12.71
|
-8.89 |
-12.71 |
|
TPVQPGGH |
21.97
|
-2.68 |
-6.50 |
|
LPTPVQPG |
22.03
|
-1.22 |
-5.04 |
| Q00246 |
LPRLPTPF |
18.55
|
-3.64 |
-7.46 |
|
NLPRLPTP |
19.93
|
-6.13 |
-9.95 |
|
EKNLPRLP |
20.12
|
-6.78 |
-10.60 |
| P32448 |
SPQLPSKD |
17.50
|
-4.46 |
-8.28 |
|
RVPTDSPQ |
22.38
|
-2.81 |
-6.63 |
| Q04439 |
KPKEPMFE |
12.87
|
-3.52 |
-7.34 |
|
PPSSKPKE |
16.82
|
-3.26 |
-7.07 |
|
SKPKEPMF |
16.88
|
-4.97 |
-8.79 |
| P35197 |
TPAKPPQE |
11.62
|
-4.52 |
-8.33 |
|
FGSTPAKP |
18.93
|
-5.36 |
-9.18 |
|
RPDHLPPS |
19.89
|
-5.04 |
-8.86 |
| Q12446 |
LPQLPNRN |
13.85
|
-9.72 |
-13.54 |
|
QPQSNPFP |
13.87
|
-6.16 |
-9.97 |
|
APPPPPRR |
14.25
|
-5.92 |
-9.73 |
| P08018 |
HPTRPNVA |
17.63
|
-6.78 |
-10.60 |
|
RPNVAPHK |
17.88
|
-5.63 |
-9.45 |
|
RAPRRPLS |
17.93
|
-6.41 |
-10.23 |
| P39969 |
SPRRAPKP |
14.20
|
-6.57 |
-10.39 |
|
SPEENPIT |
16.37
|
-3.26 |
-7.07 |
|
SPAQPPKS |
17.28
|
-3.86 |
-7.67 |
| Q03790 |
ATPSPFRP |
20.43
|
-4.48 |
-8.29 |
|
FPSAPQPL |
20.87
|
-2.77 |
-6.59 |
|
KPTATPSP |
21.24
|
-1.76 |
-5.58 |
| P41809 |
YPTTPYPS |
20.82
|
-2.82 |
-6.63 |
|
SPSVPVAV |
22.75
|
-1.13 |
-4.95 |
|
SPSAPAAI |
22.98
|
-0.23 |
-4.04 |
| Q05080 |
LRQKPDKP |
15.26
|
-6.48 |
-10.30 |
|
KPDKPRPI |
16.16
|
-2.84 |
-6.65 |
|
QKPDKPRP |
19.47
|
-6.99 |
-10.81 |
| P25344 |
TPGPSPNE |
21.14
|
-2.21 |
-6.03 |
| P53297 |
LPPKPISK |
16.12
|
-2.40 |
-6.21 |
|
MPQMMPVM |
16.78
|
-5.77 |
-9.58 |
|
VPGMNPAM |
17.14
|
-2.52 |
-6.34 |
| P22147 |
FPPPPPMT |
17.80
|
-6.16 |
-9.97 |
|
HPHQMPYP |
18.71
|
-6.62 |
-10.44 |
|
IPKGEPFD |
19.03
|
-2.90 |
-6.71 |
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