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Matrix information:
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ADAN-name: SHO1_1QKX-12.PDB
Scoring matrix: SHO1_1QKX-12_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.4
Foldx random average score for Saccharomyces cerevisiae: 10.151 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 937150
Proteins after disorder filtering: 3255
Total fragments: 77612
Proteins after pattern filtering: 1588
Total fragments: 11577
Proteins after MINT filtering: 24
Total fragments: 380 ROC parameters:
TPR= 0.429
FPR= 0.311
ACC= 0.686
SPC= 0.689
MCC= 0.026 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
12.40
|
-0.03 |
0.00 |
| Best peptides |
RWGLRRNR |
0.00
|
3.79 |
3.82 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLPLTPNS |
7.33
|
-3.69 |
-3.66 |
| Q06604 |
FEKGPRMP |
4.85
|
-4.92 |
-4.89 |
|
PRMPSRGR |
6.01
|
-6.30 |
-6.27 |
|
PSPPAKRI |
6.67
|
-3.36 |
-3.33 |
| P24583 |
LPPQPRKH |
5.33
|
-5.34 |
-5.31 |
|
PLPPQPRK |
6.96
|
-4.16 |
-4.13 |
|
NAPLPPQP |
6.97
|
-3.97 |
-3.94 |
| Q06412 |
RRPPPPPP |
6.58
|
-5.38 |
-5.35 |
|
SPKSPRDS |
6.78
|
-6.41 |
-6.38 |
|
FTKPPPPL |
6.99
|
-4.75 |
-4.72 |
| P40036 |
PTTPGIRS |
7.87
|
-4.15 |
-4.12 |
|
LPPLSPKS |
8.04
|
-4.15 |
-4.12 |
|
ELPPLSPK |
8.88
|
-2.66 |
-2.63 |
| P09620 |
PSNIPQMH |
6.98
|
-3.59 |
-3.56 |
|
SNPISKPS |
7.48
|
-3.26 |
-3.23 |
|
PDPSNIPQ |
7.86
|
-3.74 |
-3.71 |
| P13186 |
SYVPNRVP |
4.29
|
-8.37 |
-8.34 |
|
SIPMSPNY |
6.62
|
-3.65 |
-3.62 |
|
PSYVPNRV |
6.91
|
-4.89 |
-4.86 |
| P32334 |
SSPSSPTT |
8.78
|
-2.61 |
-2.58 |
| P39083 |
QSPATPSN |
9.54
|
-3.45 |
-3.42 |
| P38753 |
PVMPPQRQ |
6.54
|
-4.61 |
-4.58 |
|
PSNLPIQH |
6.66
|
-4.11 |
-4.08 |
|
TPVMPPQR |
7.10
|
-4.85 |
-4.82 |
| Q08229 |
DYNPTIPP |
7.09
|
-4.22 |
-4.19 |
|
PTIPPRSK |
7.39
|
-4.88 |
-4.85 |
|
PLPSTPNE |
7.75
|
-3.39 |
-3.36 |
| Q00246 |
EKNLPRLP |
4.54
|
-6.69 |
-6.66 |
|
NLPESPGT |
8.65
|
-3.73 |
-3.70 |
|
LPRLPTPF |
8.91
|
-4.06 |
-4.03 |
| P32448 |
DSPQLPSK |
8.88
|
-3.20 |
-3.17 |
|
VPTDSPQL |
9.91
|
-3.62 |
-3.59 |
|
RVPTDSPQ |
9.91
|
-1.82 |
-1.79 |
| Q04439 |
NIPPPPPP |
6.87
|
-4.39 |
-4.36 |
|
SKKPAPPP |
7.05
|
-1.82 |
-1.79 |
|
PTPPQNRD |
7.31
|
-4.07 |
-4.04 |
| P35197 |
PAKPPQER |
6.88
|
-3.86 |
-3.83 |
|
STPAKPPQ |
7.97
|
-3.56 |
-3.53 |
|
PDHLPPSQ |
8.07
|
-5.08 |
-5.05 |
| Q12446 |
PPPPPRRG |
4.56
|
-6.47 |
-6.44 |
|
PPPPRRGP |
5.59
|
-6.85 |
-6.82 |
|
PPPPPRAS |
5.74
|
-5.25 |
-5.22 |
| P08018 |
DGPPPRLP |
4.83
|
-4.17 |
-4.14 |
|
TQHPTRPN |
5.24
|
-4.47 |
-4.44 |
|
RAPRRPLS |
8.01
|
-3.59 |
-3.56 |
| P39969 |
PRRAPKPP |
7.58
|
-3.65 |
-3.62 |
|
PKPPSYPS |
7.65
|
-4.13 |
-4.10 |
|
PSYPSPAQ |
7.67
|
-4.95 |
-4.92 |
| Q03790 |
GFPSAPQP |
7.42
|
-2.98 |
-2.95 |
|
ATPSPFRP |
7.58
|
-4.17 |
-4.14 |
|
NGFPSAPQ |
8.15
|
-4.08 |
-4.05 |
| P41809 |
TPYPSPNS |
7.46
|
-4.95 |
-4.92 |
|
PYPSPNSY |
7.56
|
-3.65 |
-3.62 |
|
STYPTTPY |
8.41
|
-4.42 |
-4.39 |
| Q05080 |
QKPDKPRP |
6.34
|
-5.17 |
-5.14 |
|
RQKPDKPR |
6.69
|
-3.86 |
-3.83 |
|
PDKPRPIV |
7.93
|
-4.17 |
-4.14 |
| P25344 |
TPGPSPNE |
6.50
|
-1.84 |
-1.81 |
|
NTPGPSPN |
8.82
|
-2.34 |
-2.31 |
|
PGPSPNEA |
9.03
|
-3.14 |
-3.11 |
| P53297 |
PEGKPPQK |
6.25
|
-2.06 |
-2.03 |
|
GYPGGIPF |
6.31
|
-4.29 |
-4.26 |
|
GMYMPFQP |
6.52
|
-4.86 |
-4.83 |
| P22147 |
ISFPPPPP |
5.85
|
-6.02 |
-5.99 |
|
PLHPHQMP |
6.66
|
-4.17 |
-4.14 |
|
SFPPPPPM |
6.66
|
-4.84 |
-4.81 |
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