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Matrix information:
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ADAN-name: SHO1_1QKX-11.PDB
Scoring matrix: SHO1_1QKX-11_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 16.67
Foldx random average score for Saccharomyces cerevisiae: 14.375 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2186557
Proteins after random average filtering: 5078
Total fragments: 936397
Proteins after disorder filtering: 3369
Total fragments: 69535
Proteins after pattern filtering: 1536
Total fragments: 7975
Proteins after MINT filtering: 22
Total fragments: 242 ROC parameters:
TPR= 0.393
FPR= 0.301
ACC= 0.695
SPC= 0.699
MCC= 0.021 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
16.67
|
3.59 |
0.00 |
| Best peptides |
WDWKHER |
0.00
|
4.21 |
0.62 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTP |
12.39
|
-3.72 |
-7.31 |
| Q06604 |
NKPKPTP |
9.64
|
-3.12 |
-6.71 |
|
KGPRMPS |
10.06
|
-3.09 |
-6.68 |
|
GPRMPSR |
10.70
|
-4.09 |
-7.68 |
| P24583 |
NAPLPPQ |
11.61
|
-2.04 |
-5.63 |
|
LPPQPRK |
13.32
|
-2.67 |
-6.26 |
|
ANAPLPP |
13.39
|
-2.73 |
-6.32 |
| Q06412 |
NSPKSPR |
10.07
|
-2.69 |
-6.28 |
|
RRPPPPP |
11.09
|
-4.58 |
-8.17 |
|
RPPPPPP |
11.51
|
-6.00 |
-9.59 |
| P40036 |
LPTTPGI |
13.46
|
-1.45 |
-5.04 |
|
PPLSPKS |
14.20
|
-1.26 |
-4.85 |
| P09620 |
PISKPSI |
9.66
|
-3.37 |
-6.96 |
|
PDPSNIP |
9.84
|
-2.01 |
-5.60 |
|
NPISKPS |
13.97
|
-0.43 |
-4.02 |
| P13186 |
LPEREPP |
10.92
|
-4.75 |
-8.34 |
|
IPAALPP |
11.74
|
-3.23 |
-6.82 |
|
PSYVPNR |
11.99
|
-2.63 |
-6.22 |
| P38753 |
YPSNLPI |
10.71
|
-3.27 |
-6.86 |
|
LPIQHPT |
10.88
|
-3.51 |
-7.10 |
|
NTPVMPP |
11.53
|
-0.57 |
-4.16 |
| Q08229 |
NPTIPPR |
13.21
|
-4.25 |
-7.84 |
|
PTPVQPG |
13.92
|
0.53 |
-3.06 |
|
LPTPVQP |
14.25
|
-4.06 |
-7.65 |
| Q00246 |
KNLPRLP |
13.15
|
-2.55 |
-6.14 |
|
LPRLPTP |
13.42
|
-4.00 |
-7.59 |
| P32448 |
RVPTDSP |
10.82
|
-1.14 |
-4.73 |
| Q04439 |
SKPKEPM |
10.38
|
-0.83 |
-4.42 |
|
KKPAPPP |
10.60
|
-3.55 |
-7.14 |
|
NIPTPPQ |
11.17
|
-0.79 |
-4.38 |
| P35197 |
RPDHLPP |
9.85
|
-4.04 |
-7.63 |
|
PDHLPPS |
11.21
|
-3.11 |
-6.70 |
|
SRPDHLP |
11.64
|
0.00 |
-3.59 |
| Q12446 |
PPPPHRH |
10.15
|
-2.61 |
-6.20 |
|
NPFPFPI |
10.50
|
-2.90 |
-6.49 |
|
NRPVPPP |
10.84
|
-2.50 |
-6.09 |
| P08018 |
RAPRRPL |
10.88
|
-3.95 |
-7.54 |
|
PPPRLPS |
11.02
|
-4.69 |
-8.28 |
|
HPTRPNV |
12.00
|
-1.27 |
-4.86 |
| P39969 |
RAPKPPS |
8.76
|
-3.62 |
-7.21 |
|
PIPSPTR |
11.85
|
-3.64 |
-7.23 |
|
VSPRRAP |
12.04
|
-2.69 |
-6.28 |
| Q03790 |
PTATPSP |
12.83
|
-1.12 |
-4.71 |
|
GFPSAPQ |
13.11
|
-0.25 |
-3.84 |
|
TPSPFRP |
13.69
|
-2.38 |
-5.97 |
| P41809 |
YPTTPYP |
11.19
|
-2.60 |
-6.19 |
|
PYPSPNS |
13.75
|
-0.95 |
-4.54 |
|
PSAPVAI |
14.18
|
-0.66 |
-4.25 |
| Q05080 |
KPDKPRP |
8.57
|
-4.17 |
-7.76 |
|
PDKPRPI |
11.72
|
-1.42 |
-5.01 |
|
RQKPDKP |
11.76
|
-1.57 |
-5.16 |
| P25344 |
NTPGPSP |
13.85
|
0.10 |
-3.49 |
| P53297 |
PEGKPPQ |
7.62
|
-2.85 |
-6.44 |
|
MYMPFQP |
9.55
|
-2.96 |
-6.55 |
|
NISPHVP |
9.74
|
-2.06 |
-5.65 |
| P22147 |
PTPPHPM |
9.39
|
-1.43 |
-5.02 |
|
QPISFPP |
9.99
|
-2.80 |
-6.39 |
|
LHPLHPH |
10.38
|
-1.73 |
-5.32 |
|
