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Matrix information:
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ADAN-name: SHO1_1QCF-9.PDB
Scoring matrix: SHO1_1QCF-9_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 11.52
Foldx random average score for Saccharomyces cerevisiae: 12.603 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 1083492
Proteins after disorder filtering: 3341
Total fragments: 113492
Proteins after pattern filtering: 1631
Total fragments: 14887
Proteins after MINT filtering: 24
Total fragments: 524 ROC parameters:
TPR= 0.429
FPR= 0.32
ACC= 0.677
SPC= 0.68
MCC= 0.024 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
11.52
|
-2.79 |
0.00 |
| Best peptides |
RPYMPEVW |
0.00
|
-0.24 |
2.54 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNSK |
4.35
|
-5.04 |
-2.25 |
|
KPLPLTPN |
6.06
|
-5.66 |
-2.88 |
| Q06604 |
KPTPPSPP |
3.54
|
-9.13 |
-6.35 |
|
KPAPPVSR |
4.41
|
-7.00 |
-4.21 |
|
PKPTPPSP |
4.60
|
-7.72 |
-4.93 |
| P24583 |
RANAPLPP |
4.84
|
-8.63 |
-5.85 |
|
APLPPQPR |
6.82
|
-6.30 |
-3.51 |
|
ANAPLPPQ |
7.65
|
-6.21 |
-3.42 |
| Q06412 |
RPPPPPPL |
2.28
|
-12.06 |
-9.28 |
|
RRPPPPPP |
2.31
|
-10.57 |
-7.79 |
|
KPPPPLST |
3.34
|
-7.16 |
-4.38 |
| P40036 |
LPTTPGIR |
3.43
|
-6.17 |
-3.38 |
|
IELPPLSP |
5.17
|
-7.97 |
-5.18 |
|
PPLSPKST |
6.79
|
-8.15 |
-5.37 |
| P09620 |
NPISKPSI |
7.17
|
-6.13 |
-3.34 |
|
VPDPSNIP |
7.95
|
-6.21 |
-3.42 |
|
PDPSNIPQ |
9.86
|
-5.31 |
-2.52 |
| P13186 |
IPLTPLAT |
4.65
|
-5.33 |
-2.54 |
|
IPAALPPS |
5.59
|
-8.75 |
-5.96 |
|
PEREPPTY |
5.88
|
-7.63 |
-4.84 |
| P32334 |
DFSSPSSP |
7.65
|
-4.53 |
-1.75 |
|
SPSSPTTT |
8.26
|
-6.94 |
-4.16 |
|
FSSPSSPT |
8.73
|
-4.56 |
-1.77 |
| P39083 |
LLQSPATP |
5.56
|
-7.99 |
-5.21 |
|
SPATPSNV |
7.21
|
-5.13 |
-2.34 |
|
LQSPATPS |
8.88
|
-5.80 |
-3.01 |
| P38753 |
YPSNLPIQ |
5.54
|
-5.66 |
-2.88 |
|
AHISPPVP |
6.83
|
-7.17 |
-4.38 |
|
LPIQHPTN |
6.92
|
-6.72 |
-3.93 |
| Q08229 |
NDYNPTIP |
5.14
|
-8.16 |
-5.38 |
|
LPSTPNED |
6.10
|
-8.05 |
-5.27 |
|
TPVQPGGH |
6.38
|
-7.47 |
-4.68 |
| Q00246 |
LPESPGTL |
3.60
|
-5.83 |
-3.04 |
|
KNLPRLPT |
7.47
|
-6.23 |
-3.45 |
|
NLPESPGT |
7.69
|
-3.86 |
-1.07 |
| P32448 |
DSPQLPSK |
7.42
|
-5.20 |
-2.42 |
|
RVPTDSPQ |
7.95
|
-6.99 |
-4.21 |
|
PRVPTDSP |
8.10
|
-5.04 |
-2.25 |
| Q04439 |
IPPPPPPP |
3.00
|
-7.60 |
-4.81 |
|
KKPAPPPP |
3.07
|
-9.91 |
-7.13 |
|
KPAPPPPG |
3.79
|
-9.30 |
-6.52 |
| P35197 |
RPDHLPPS |
4.06
|
-9.99 |
-7.21 |
|
SRPDHLPP |
8.08
|
-6.01 |
-3.22 |
|
QSRPDHLP |
9.26
|
-7.16 |
-4.38 |
| Q12446 |
RPVPPPPP |
2.26
|
-11.47 |
-8.69 |
|
LPAPPPPP |
2.62
|
-6.99 |
-4.21 |
|
RLPAPPPP |
2.92
|
-10.01 |
-7.22 |
| P08018 |
QHPTRPNV |
8.35
|
-5.62 |
-2.84 |
|
PRRPLSTQ |
8.43
|
-7.27 |
-4.48 |
|
GPPPRLPS |
8.90
|
-7.16 |
-4.38 |
| P39969 |
LPPQPGSK |
2.61
|
-5.14 |
-2.35 |
|
KPPSYPSP |
4.01
|
-6.21 |
-3.42 |
|
RRAPKPPS |
6.04
|
-7.22 |
-4.43 |
| Q03790 |
FPSAPQPL |
4.78
|
-8.89 |
-6.11 |
|
KPTATPSP |
5.06
|
-6.14 |
-3.35 |
|
PTATPSPF |
8.21
|
-6.69 |
-3.91 |
| P41809 |
YPTTPYPS |
4.37
|
-5.43 |
-2.64 |
|
LSTYPTTP |
6.02
|
-7.27 |
-4.48 |
|
SPSAPVAI |
7.25
|
-7.48 |
-4.70 |
| Q05080 |
RQKPDKPR |
8.12
|
-6.98 |
-4.20 |
|
KPDKPRPI |
9.07
|
-10.94 |
-8.15 |
|
PDKPRPIV |
9.50
|
-6.45 |
-3.67 |
| P25344 |
ANTPGPSP |
9.03
|
-3.47 |
-0.69 |
|
NTPGPSPN |
9.51
|
-5.76 |
-2.97 |
|
TPGPSPNE |
10.05
|
-1.51 |
1.28 |
| P53297 |
MPFQPQPM |
3.13
|
-9.44 |
-6.65 |
|
MPQMMPVM |
3.68
|
-6.91 |
-4.13 |
|
MAAGPGAP |
6.36
|
-6.88 |
-4.09 |
| P22147 |
IPTPPHPM |
4.43
|
-5.39 |
-2.60 |
|
ISFPPPPP |
4.66
|
-9.41 |
-6.63 |
|
QPISFPPP |
5.53
|
-6.81 |
-4.02 |
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