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Matrix information:
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ADAN-name: SHO1_1QCF-8.PDB
Scoring matrix: SHO1_1QCF-8_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.57
Foldx random average score for Saccharomyces cerevisiae: 11.797 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5077
Total fragments: 1221488
Proteins after disorder filtering: 3340
Total fragments: 116576
Proteins after pattern filtering: 1620
Total fragments: 14862
Proteins after MINT filtering: 24
Total fragments: 494 ROC parameters:
TPR= 0.429
FPR= 0.318
ACC= 0.679
SPC= 0.682
MCC= 0.025 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
12.57
|
-1.48 |
0.00 |
| Best peptides |
HWEPIDPK |
0.00
|
5.40 |
6.88 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
LPLTPNSK |
7.22
|
-5.63 |
-4.15 |
|
SKPLPLTP |
7.73
|
-4.46 |
-2.98 |
|
PLPLTPNS |
10.48
|
-2.80 |
-1.32 |
| Q06604 |
TPPSPPAK |
5.88
|
-4.93 |
-3.45 |
|
SSPPPLPT |
6.00
|
-2.00 |
-0.52 |
|
NEEKPLLP |
6.12
|
-5.26 |
-3.78 |
| P24583 |
APLPPQPR |
6.42
|
-6.89 |
-5.41 |
|
RANAPLPP |
6.92
|
-5.97 |
-4.49 |
|
LPPQPRKH |
7.60
|
-3.01 |
-1.53 |
| Q06412 |
RRPPPPPP |
4.48
|
-6.23 |
-4.75 |
|
ERRPPPPP |
4.65
|
-7.26 |
-5.78 |
|
KPPPPLST |
5.89
|
-4.47 |
-2.99 |
| P40036 |
LPPLSPKS |
7.17
|
-3.30 |
-1.82 |
|
IELPPLSP |
7.52
|
-5.70 |
-4.22 |
|
PPLSPKST |
8.90
|
-3.28 |
-1.80 |
| P09620 |
VPDPSNIP |
6.83
|
-4.50 |
-3.02 |
|
SNPISKPS |
7.35
|
-0.77 |
0.71 |
|
LSNPISKP |
7.87
|
-4.40 |
-2.92 |
| P13186 |
LPEREPPT |
4.04
|
-4.65 |
-3.17 |
|
EPLPEREP |
5.53
|
-5.52 |
-4.04 |
|
APSYVPNR |
6.38
|
-6.46 |
-4.98 |
| P32334 |
SSPSSPTT |
8.63
|
-0.94 |
0.54 |
|
FSSPSSPT |
9.54
|
-0.51 |
0.97 |
|
DFSSPSSP |
10.23
|
-2.38 |
-0.90 |
| P39083 |
QSPATPSN |
8.29
|
-2.92 |
-1.44 |
|
PATPSNVS |
9.63
|
-2.19 |
-0.71 |
|
SPATPSNV |
11.62
|
-2.93 |
-1.45 |
| P38753 |
ISPPVPGP |
6.02
|
-4.80 |
-3.32 |
|
NNTPVMPP |
6.18
|
-4.94 |
-3.46 |
|
SNLPIQHP |
6.47
|
-5.37 |
-3.89 |
| Q08229 |
YNPTIPPR |
3.82
|
-8.56 |
-7.08 |
|
PTIPPRSK |
7.83
|
-3.43 |
-1.95 |
|
TRPLPSTP |
8.11
|
-1.85 |
-0.37 |
| Q00246 |
PRLPTPFA |
7.46
|
-5.73 |
-4.25 |
|
EKNLPRLP |
8.19
|
-4.76 |
-3.28 |
|
SSNLPESP |
8.60
|
-3.47 |
-1.99 |
| P32448 |
PRVPTDSP |
5.73
|
-6.83 |
-5.35 |
|
TDSPQLPS |
7.66
|
-2.83 |
-1.35 |
|
PQLPSKDK |
8.56
|
-3.37 |
-1.89 |
| Q04439 |
IPPPPPPP |
5.29
|
-6.76 |
-5.28 |
|
PPPPPPPP |
5.31
|
-7.61 |
-6.13 |
|
PPPPPPPS |
5.61
|
-6.02 |
-4.54 |
| P35197 |
SRPDHLPP |
4.17
|
-6.23 |
-4.75 |
|
PAKPPQER |
7.33
|
-4.70 |
-3.22 |
|
QSRPDHLP |
7.72
|
-3.80 |
-2.32 |
| Q12446 |
NNRPVPPP |
4.83
|
-7.09 |
-5.61 |
|
APPPPPHR |
5.08
|
-7.14 |
-5.66 |
|
APPPPPRR |
5.24
|
-8.85 |
-7.37 |
| P08018 |
APRRPLST |
6.20
|
-4.31 |
-2.83 |
|
RPNVAPHK |
6.34
|
-6.25 |
-4.77 |
|
PRLPSDKF |
7.27
|
-5.02 |
-3.54 |
| P39969 |
SPEENPIT |
5.45
|
-3.88 |
-2.40 |
|
PSPAQPPK |
5.50
|
-5.84 |
-4.36 |
|
SSPEENPI |
5.88
|
-1.41 |
0.07 |
| Q03790 |
KPTATPSP |
7.87
|
-7.38 |
-5.90 |
|
GFPSAPQP |
7.99
|
-4.03 |
-2.55 |
|
FPSAPQPL |
8.21
|
-4.51 |
-3.03 |
| P41809 |
SSPSVPVA |
7.63
|
-2.23 |
-0.75 |
|
YPTTPYPS |
7.84
|
-4.28 |
-2.80 |
|
SSPSAPAA |
8.48
|
-3.02 |
-1.54 |
| Q05080 |
LRQKPDKP |
5.94
|
-5.75 |
-4.27 |
|
KPDKPRPI |
6.18
|
-3.99 |
-2.51 |
|
RQKPDKPR |
6.83
|
-4.67 |
-3.19 |
| P25344 |
ANTPGPSP |
8.16
|
-2.74 |
-1.26 |
|
PGPSPNEA |
8.38
|
-1.53 |
-0.05 |
|
NTPGPSPN |
10.99
|
-1.17 |
0.31 |
| P53297 |
YMPFQPQP |
7.34
|
-5.73 |
-4.25 |
|
PSMPQMMP |
7.49
|
-4.32 |
-2.84 |
|
ISPHVPAG |
7.79
|
-3.05 |
-1.57 |
| P22147 |
QPISFPPP |
6.20
|
-8.07 |
-6.59 |
|
FPPPPPMT |
6.22
|
-5.08 |
-3.60 |
|
LHPLHPHQ |
6.60
|
-3.40 |
-1.92 |
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