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Matrix information:
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ADAN-name: SHO1_1QCF-7.PDB
Scoring matrix: SHO1_1QCF-7_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 11.88
Foldx random average score for Saccharomyces cerevisiae: 15.960 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 951645
Proteins after disorder filtering: 3319
Total fragments: 73028
Proteins after pattern filtering: 1644
Total fragments: 13789
Proteins after MINT filtering: 24
Total fragments: 464 ROC parameters:
TPR= 0.429
FPR= 0.323
ACC= 0.675
SPC= 0.677
MCC= 0.024 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AGAAAAAA |
11.88
|
-3.25 |
0.00 |
| Best peptides |
MRRPPPKH |
0.00
|
-2.04 |
1.21 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPN |
5.00
|
-7.42 |
-4.17 |
|
PLTPNSKY |
9.52
|
-7.14 |
-3.89 |
| Q06604 |
PPSPPAKR |
4.88
|
-9.19 |
-5.94 |
|
KPAPPVSR |
5.62
|
-7.46 |
-4.21 |
|
VKPAPPVS |
5.85
|
-8.07 |
-4.82 |
| P24583 |
APLPPQPR |
6.17
|
-8.11 |
-4.86 |
|
ANAPLPPQ |
6.70
|
-6.39 |
-3.14 |
|
PLPPQPRK |
8.29
|
-9.34 |
-6.09 |
| Q06412 |
RPPPPPPL |
3.98
|
-9.34 |
-6.09 |
|
RRPPPPPP |
4.66
|
-9.09 |
-5.84 |
|
TKPPPPLS |
5.67
|
-8.61 |
-5.36 |
| P40036 |
ELPPLSPK |
4.97
|
-7.36 |
-4.11 |
|
IELPPLSP |
8.78
|
-5.70 |
-2.45 |
|
PLSPKSTV |
9.73
|
-5.99 |
-2.74 |
| P09620 |
VPDPSNIP |
8.47
|
-5.90 |
-2.65 |
|
PISKPSIH |
12.75
|
-7.60 |
-4.35 |
|
SNPISKPS |
15.10
|
-3.54 |
-0.29 |
| P13186 |
IPAALPPS |
6.48
|
-4.66 |
-1.41 |
|
NNIPLTPL |
7.46
|
-4.79 |
-1.54 |
|
PLTPLATN |
7.54
|
-6.58 |
-3.33 |
| P32334 |
FSSPSSPT |
8.49
|
-4.61 |
-1.36 |
|
PSSPTTTD |
13.01
|
-3.05 |
0.20 |
| P39083 |
PATPSNVS |
9.54
|
-4.01 |
-0.76 |
|
QSPATPSN |
11.77
|
-3.39 |
-0.14 |
|
LQSPATPS |
12.38
|
-5.28 |
-2.03 |
| P38753 |
HISPPVPG |
7.79
|
-6.95 |
-3.70 |
|
PPVPGPAL |
9.87
|
-5.14 |
-1.89 |
|
SPYPSNLP |
10.16
|
-4.99 |
-1.74 |
| Q08229 |
RPLPSTPN |
5.69
|
-5.13 |
-1.88 |
|
PTIPPRSK |
8.02
|
-6.83 |
-3.58 |
|
PSTPNEDS |
10.82
|
-4.37 |
-1.12 |
| Q00246 |
KNLPRLPT |
8.68
|
-4.97 |
-1.72 |
|
SNLPESPG |
9.39
|
-5.13 |
-1.88 |
|
PRLPTPFA |
9.87
|
-4.23 |
-0.98 |
| P32448 |
TDSPQLPS |
6.80
|
-5.25 |
-2.00 |
|
PQLPSKDK |
9.26
|
-4.01 |
-0.76 |
|
PRVPTDSP |
12.61
|
-4.22 |
-0.97 |
| Q04439 |
KPAPPPPG |
5.17
|
-9.08 |
-5.83 |
|
IPTPPQNR |
6.04
|
-5.52 |
-2.27 |
|
PPPPPPPS |
6.13
|
-8.82 |
-5.57 |
| P35197 |
PAKPPQER |
7.18
|
-6.92 |
-3.67 |
|
STPAKPPQ |
8.84
|
-4.86 |
-1.61 |
|
QSRPDHLP |
9.51
|
-6.20 |
-2.95 |
| Q12446 |
PAPPPPPH |
4.89
|
-8.77 |
-5.52 |
|
PAPPPPPR |
5.45
|
-8.83 |
-5.58 |
|
RPLPQLPN |
5.59
|
-5.45 |
-2.20 |
| P08018 |
PRLPSDKF |
4.70
|
-5.60 |
-2.35 |
|
PRRPLSTQ |
5.94
|
-6.50 |
-3.25 |
|
GPPPRLPS |
9.74
|
-4.12 |
-0.87 |
| P39969 |
RRAPKPPS |
5.57
|
-7.70 |
-4.45 |
|
KLLPPQPG |
5.90
|
-8.19 |
-4.94 |
|
PSPAQPPK |
6.86
|
-5.72 |
-2.47 |
| Q03790 |
PSAPQPLF |
6.79
|
-6.16 |
-2.91 |
|
FPSAPQPL |
7.37
|
-7.18 |
-3.93 |
|
NGFPSAPQ |
8.30
|
-3.91 |
-0.66 |
| P41809 |
TSSPSVPV |
7.69
|
-3.70 |
-0.45 |
|
TSSPSAPV |
7.89
|
-3.71 |
-0.46 |
|
TSSPSAPA |
7.94
|
-3.30 |
-0.05 |
| Q05080 |
RQKPDKPR |
5.49
|
-7.59 |
-4.34 |
|
PDKPRPIV |
7.50
|
-6.71 |
-3.46 |
|
KPDKPRPI |
12.17
|
-8.54 |
-5.29 |
| P25344 |
TPGPSPNE |
8.40
|
-2.71 |
0.54 |
|
NTPGPSPN |
8.78
|
-5.26 |
-2.01 |
|
ANTPGPSP |
13.09
|
-3.80 |
-0.55 |
| P53297 |
MYMPFQPQ |
6.09
|
-6.52 |
-3.27 |
|
SSLPPKPI |
7.53
|
-6.77 |
-3.52 |
|
FYHPSMPQ |
7.58
|
-4.99 |
-1.74 |
| P22147 |
SFPPPPPM |
4.52
|
-7.51 |
-4.26 |
|
SIPPPAPH |
5.33
|
-7.09 |
-3.84 |
|
IPTPPHPM |
5.75
|
-5.62 |
-2.37 |
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