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Matrix information:
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ADAN-name: SHO1_1QCF-26.PDB
Scoring matrix: SHO1_1QCF-26_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 12.18
Foldx random average score for Saccharomyces cerevisiae: 14.001 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2176401
Proteins after random average filtering: 5077
Total fragments: 988470
Proteins after disorder filtering: 3229
Total fragments: 83767
Proteins after pattern filtering: 1615
Total fragments: 15008
Proteins after MINT filtering: 24
Total fragments: 523 ROC parameters:
TPR= 0.429
FPR= 0.317
ACC= 0.68
SPC= 0.683
MCC= 0.025 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
12.18
|
-0.15 |
0.00 |
| Best peptides |
DDMKRHFPS |
0.00
|
-1.40 |
-1.25 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
PLPLTPNSK |
9.21
|
-7.11 |
-6.96 |
|
KPLPLTPNS |
12.65
|
-5.70 |
-5.55 |
| Q06604 |
KPKPTPPSP |
4.62
|
-7.28 |
-7.13 |
|
RVKPAPPVS |
4.84
|
-7.17 |
-7.02 |
|
SSSPPPLPT |
6.90
|
-5.75 |
-5.60 |
| P24583 |
ERANAPLPP |
6.94
|
-7.24 |
-7.09 |
|
ANAPLPPQP |
7.64
|
-6.96 |
-6.81 |
|
PLPPQPRKH |
9.00
|
-8.50 |
-8.35 |
| Q06412 |
ERRPPPPPP |
3.74
|
-8.54 |
-8.39 |
|
KERRPPPPP |
3.82
|
-8.52 |
-8.37 |
|
TKPPPPLST |
4.18
|
-8.16 |
-8.01 |
| P40036 |
KIELPPLSP |
6.64
|
-6.23 |
-6.08 |
|
LPPLSPKST |
6.72
|
-5.66 |
-5.51 |
|
ELPPLSPKS |
11.76
|
-7.05 |
-6.90 |
| P09620 |
PSNIPQMHA |
10.66
|
-3.45 |
-3.30 |
|
DPSNIPQMH |
11.73
|
-3.21 |
-3.06 |
|
KLSNPISKP |
12.87
|
-2.47 |
-2.32 |
| P13186 |
DQQQAPLMP |
6.72
|
-5.12 |
-4.97 |
|
PPIPAALPP |
7.08
|
-5.93 |
-5.78 |
|
NIPLTPLAT |
7.20
|
-7.07 |
-6.92 |
| P32334 |
ADFSSPSSP |
9.71
|
-2.78 |
-2.63 |
|
SSPSSPTTT |
10.27
|
-3.25 |
-3.10 |
|
FSSPSSPTT |
13.91
|
-4.58 |
-4.43 |
| P39083 |
HLLQSPATP |
9.16
|
-4.18 |
-4.03 |
|
LLQSPATPS |
10.47
|
-1.84 |
-1.69 |
| P38753 |
PVMPPQRQS |
6.46
|
-4.03 |
-3.88 |
|
ISPPVPGPA |
7.52
|
-4.76 |
-4.61 |
|
SNLPIQHPT |
8.02
|
-4.89 |
-4.74 |
| Q08229 |
YNPTIPPRS |
6.07
|
-7.36 |
-7.21 |
|
LTRPLPSTP |
7.81
|
-5.61 |
-5.46 |
|
LPTPVQPGG |
9.88
|
-5.68 |
-5.53 |
| Q00246 |
DEKNLPRLP |
5.96
|
-4.65 |
-4.50 |
|
EKNLPRLPT |
8.44
|
-11.04 |
-10.89 |
|
SSSNLPESP |
9.74
|
-3.66 |
-3.51 |
| P32448 |
DSPQLPSKD |
9.48
|
-2.99 |
-2.84 |
|
PTDSPQLPS |
9.50
|
-4.25 |
-4.10 |
|
VPTDSPQLP |
11.67
|
-2.74 |
-2.59 |
| Q04439 |
PPPPPPPPS |
4.06
|
-8.81 |
-8.66 |
|
PPPPPPPSS |
4.10
|
-8.62 |
-8.47 |
|
IPPPPPPPP |
4.60
|
-8.82 |
-8.67 |
| P35197 |
QSRPDHLPP |
5.39
|
-7.25 |
-7.10 |
|
PAKPPQERS |
7.59
|
-4.98 |
-4.83 |
|
TPAKPPQER |
9.14
|
-6.89 |
-6.74 |
| Q12446 |
KAPPPPPPT |
3.84
|
-7.78 |
-7.63 |
|
VAPPPPPAS |
4.69
|
-8.27 |
-8.12 |
|
APPPPPRAS |
4.76
|
-7.08 |
-6.93 |
| P08018 |
RAPRRPLST |
3.83
|
-6.50 |
-6.35 |
|
DGPPPRLPS |
4.96
|
-12.86 |
-12.71 |
|
VDGPPPRLP |
7.64
|
-5.58 |
-5.43 |
| P39969 |
PKPPSYPSP |
5.41
|
-8.10 |
-7.95 |
|
SPRRAPKPP |
6.25
|
-5.34 |
-5.19 |
|
VSPRRAPKP |
6.31
|
-6.90 |
-6.75 |
| Q03790 |
TATPSPFRP |
7.09
|
-5.79 |
-5.64 |
|
DGKPTATPS |
7.56
|
-3.95 |
-3.80 |
|
NGFPSAPQP |
8.06
|
-6.45 |
-6.30 |
| P41809 |
TYPTTPYPS |
4.09
|
-6.87 |
-6.72 |
|
TSSPSAPAA |
8.09
|
-5.24 |
-5.09 |
|
TSSPSAPVA |
8.59
|
-4.90 |
-4.75 |
| Q05080 |
PDKPRPIVG |
8.98
|
-7.33 |
-7.18 |
|
LRQKPDKPR |
10.06
|
-8.27 |
-8.12 |
|
RQKPDKPRP |
10.61
|
-7.99 |
-7.84 |
| P25344 |
TPGPSPNEA |
7.85
|
-4.36 |
-4.21 |
|
TANTPGPSP |
8.66
|
-4.07 |
-3.92 |
| P53297 |
MGMYMPFQP |
5.87
|
-6.83 |
-6.68 |
|
MYMPFQPQP |
6.93
|
-7.16 |
-7.01 |
|
PHVPAGFMA |
7.09
|
-5.02 |
-4.87 |
| P22147 |
SFPPPPPMT |
5.40
|
-7.21 |
-7.06 |
|
IPKGEPFDS |
5.75
|
-6.39 |
-6.24 |
|
GQPISFPPP |
6.18
|
-7.78 |
-7.63 |
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