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Matrix information:
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ADAN-name: SHO1_1QCF-23.PDB
Scoring matrix: SHO1_1QCF-23_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 10.88
Foldx random average score for Saccharomyces cerevisiae: 16.251 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2186557
Proteins after random average filtering: 5078
Total fragments: 1206283
Proteins after disorder filtering: 3382
Total fragments: 125665
Proteins after pattern filtering: 1626
Total fragments: 11466
Proteins after MINT filtering: 24
Total fragments: 423 ROC parameters:
TPR= 0.429
FPR= 0.319
ACC= 0.678
SPC= 0.681
MCC= 0.025 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAA |
10.88
|
-1.79 |
0.00 |
| Best peptides |
KKDRRYM |
0.00
|
2.01 |
3.80 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTP |
11.61
|
-6.09 |
-4.30 |
|
PLTPNSK |
14.24
|
-4.63 |
-2.84 |
| Q06604 |
KGPRMPS |
5.93
|
-5.61 |
-3.82 |
|
VKPAPPV |
7.38
|
-4.26 |
-2.47 |
|
NIPSSKP |
9.34
|
-3.85 |
-2.06 |
| P24583 |
PLPPQPR |
12.54
|
-2.64 |
-0.85 |
|
PPQPRKH |
13.39
|
-4.26 |
-2.47 |
|
APLPPQP |
13.53
|
-5.31 |
-3.52 |
| Q06412 |
FSPNSPK |
7.12
|
-2.14 |
-0.35 |
|
SPMVSPS |
9.63
|
-0.73 |
1.06 |
|
SPKSPRD |
9.80
|
-2.14 |
-0.35 |
| P40036 |
PPLSPKS |
9.09
|
-3.09 |
-1.30 |
|
KSLPTTP |
12.30
|
-5.30 |
-3.51 |
|
ELPPLSP |
13.59
|
-2.88 |
-1.09 |
| P09620 |
NPISKPS |
8.40
|
-4.36 |
-2.57 |
|
DPSNIPQ |
8.91
|
1.16 |
2.95 |
|
PDPSNIP |
9.19
|
-4.00 |
-2.21 |
| P13186 |
KAPSYVP |
8.06
|
-4.01 |
-2.22 |
|
PIPAALP |
8.16
|
-5.16 |
-3.37 |
|
PSYVPNR |
8.71
|
-3.96 |
-2.17 |
| P32334 |
SPSSPTT |
10.09
|
-1.33 |
0.46 |
|
SSPSSPT |
10.27
|
-2.49 |
-0.70 |
|
FSSPSSP |
12.45
|
-4.78 |
-2.99 |
| P39083 |
QSPATPS |
7.70
|
-3.93 |
-2.14 |
|
PATPSNV |
15.10
|
-3.59 |
-1.80 |
| P38753 |
PVPGPAL |
8.50
|
-4.07 |
-2.28 |
|
SPPVPGP |
8.60
|
-3.76 |
-1.97 |
|
NTPVMPP |
9.05
|
-2.05 |
-0.26 |
| Q08229 |
PLPSTPN |
9.82
|
-3.28 |
-1.49 |
|
PTPVQPG |
9.94
|
-2.36 |
-0.57 |
|
PTIPPRS |
12.43
|
-4.14 |
-2.35 |
| Q00246 |
NLPRLPT |
7.57
|
-2.27 |
-0.48 |
|
KNLPRLP |
10.89
|
-6.60 |
-4.81 |
|
PRLPTPF |
12.47
|
-4.55 |
-2.76 |
| P32448 |
PTDSPQL |
7.50
|
-5.04 |
-3.25 |
|
VPTDSPQ |
9.69
|
-0.99 |
0.80 |
|
TDSPQLP |
14.06
|
-3.58 |
-1.79 |
| Q04439 |
KKPAPPP |
5.33
|
-5.57 |
-3.78 |
|
PPSSKPK |
7.80
|
-2.91 |
-1.12 |
|
PPPSSKP |
8.48
|
-4.38 |
-2.59 |
| P35197 |
STPAKPP |
8.63
|
-3.99 |
-2.20 |
|
SRPDHLP |
10.20
|
-0.51 |
1.28 |
|
TPAKPPQ |
12.50
|
-2.62 |
-0.83 |
| Q12446 |
PPPRRGP |
5.81
|
-3.63 |
-1.84 |
|
QPAVPLP |
6.97
|
-3.75 |
-1.96 |
|
APSAPIP |
7.58
|
-3.50 |
-1.71 |
| P08018 |
PPPRLPS |
7.05
|
-2.64 |
-0.85 |
|
APRRPLS |
7.83
|
-6.17 |
-4.38 |
|
TRPNVAP |
9.04
|
-1.42 |
0.37 |
| P39969 |
VSPRRAP |
6.11
|
-3.56 |
-1.77 |
|
SPRRAPK |
7.17
|
-2.24 |
-0.45 |
|
PEENPIT |
7.22
|
-0.67 |
1.12 |
| Q03790 |
FPSAPQP |
6.96
|
-4.27 |
-2.48 |
|
KPTATPS |
7.74
|
-4.84 |
-3.05 |
|
GFPSAPQ |
9.20
|
-2.24 |
-0.45 |
| P41809 |
SPSAPAA |
9.25
|
-2.42 |
-0.63 |
|
SPSAPVA |
9.55
|
-2.33 |
-0.54 |
|
SPSVPVA |
9.75
|
-2.10 |
-0.31 |
| Q05080 |
QKPDKPR |
6.70
|
0.97 |
2.76 |
|
KPDKPRP |
7.87
|
-6.63 |
-4.84 |
|
PDKPRPI |
12.75
|
-5.94 |
-4.15 |
| P25344 |
NTPGPSP |
9.75
|
-3.08 |
-1.29 |
|
PGPSPNE |
9.77
|
-3.44 |
-1.65 |
|
TPGPSPN |
15.58
|
-1.01 |
0.78 |
| P53297 |
APEGKPP |
7.63
|
-3.97 |
-2.18 |
|
PGMNPAM |
7.74
|
-1.52 |
0.27 |
|
AGPGAPM |
8.42
|
-3.47 |
-1.68 |
| P22147 |
QPISFPP |
5.93
|
-5.72 |
-3.93 |
|
PHQMPYP |
8.94
|
-5.45 |
-3.66 |
|
PPPAPHG |
8.97
|
-4.21 |
-2.42 |
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