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Matrix information:
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ADAN-name: SHO1_1QCF-13.PDB
Scoring matrix: SHO1_1QCF-13_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.65
Foldx random average score for Saccharomyces cerevisiae: 18.449 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 1022003
Proteins after disorder filtering: 3305
Total fragments: 89805
Proteins after pattern filtering: 1630
Total fragments: 14784
Proteins after MINT filtering: 24
Total fragments: 490 ROC parameters:
TPR= 0.429
FPR= 0.32
ACC= 0.677
SPC= 0.68
MCC= 0.024 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
15.65
|
1.11 |
0.00 |
| Best peptides |
RDEQFPSK |
0.00
|
1.90 |
0.79 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPN |
8.33
|
-3.61 |
-4.72 |
|
LPLTPNSK |
13.60
|
-4.79 |
-5.90 |
|
PLTPNSKY |
13.75
|
-3.84 |
-4.95 |
| Q06604 |
KPTPPSPP |
5.98
|
-5.78 |
-6.89 |
|
KPAPPVSR |
6.93
|
-5.55 |
-6.66 |
|
SSPPPLPT |
8.04
|
-3.78 |
-4.89 |
| P24583 |
LPPQPRKH |
7.32
|
-6.83 |
-7.94 |
|
RANAPLPP |
9.13
|
-5.83 |
-6.94 |
|
APLPPQPR |
10.10
|
-5.05 |
-6.16 |
| Q06412 |
RPPPPPPL |
3.85
|
-7.75 |
-8.86 |
|
RRPPPPPP |
3.87
|
-9.00 |
-10.11 |
|
KPPPPLST |
4.02
|
-4.81 |
-5.92 |
| P40036 |
IELPPLSP |
7.84
|
-5.93 |
-7.04 |
|
ELPPLSPK |
9.12
|
-4.47 |
-5.58 |
|
KSLPTTPG |
12.24
|
-1.86 |
-2.97 |
| P09620 |
SNPISKPS |
11.36
|
-1.36 |
-2.47 |
|
PDPSNIPQ |
14.82
|
-2.73 |
-3.84 |
|
LSNPISKP |
16.99
|
-4.22 |
-5.33 |
| P13186 |
RPPIPAAL |
3.94
|
-8.43 |
-9.54 |
|
NSSIPMSP |
8.08
|
-4.86 |
-5.97 |
|
PLPEREPP |
8.96
|
-4.83 |
-5.94 |
| P32334 |
FSSPSSPT |
12.03
|
-1.79 |
-2.90 |
|
DFSSPSSP |
16.66
|
-4.45 |
-5.56 |
|
SPSSPTTT |
17.04
|
-4.18 |
-5.29 |
| P39083 |
LQSPATPS |
11.52
|
-3.10 |
-4.21 |
|
QSPATPSN |
12.01
|
-1.24 |
-2.35 |
|
LLQSPATP |
18.22
|
-4.89 |
-6.00 |
| P38753 |
NLPIQHPT |
8.61
|
-3.86 |
-4.97 |
|
LPIQHPTN |
9.82
|
-5.79 |
-6.90 |
|
HISPPVPG |
10.17
|
-5.71 |
-6.82 |
| Q08229 |
TPVQPGGH |
7.98
|
-4.48 |
-5.59 |
|
RPLPSTPN |
9.53
|
-3.64 |
-4.75 |
|
PTIPPRSK |
10.44
|
-2.72 |
-3.83 |
| Q00246 |
KNLPRLPT |
9.51
|
-2.30 |
-3.41 |
|
NLPESPGT |
10.81
|
-2.42 |
-3.53 |
|
SNLPESPG |
12.07
|
-2.46 |
-3.57 |
| P32448 |
DSPQLPSK |
8.22
|
-2.49 |
-3.60 |
|
TDSPQLPS |
8.82
|
-2.37 |
-3.48 |
|
PRVPTDSP |
11.86
|
-2.65 |
-3.76 |
| Q04439 |
KKPAPPPP |
4.93
|
-6.66 |
-7.77 |
|
PPPPPPSS |
5.89
|
-5.23 |
-6.34 |
|
PPPPPSSK |
5.89
|
-4.85 |
-5.96 |
| P35197 |
RPDHLPPS |
6.36
|
-7.14 |
-8.25 |
|
SRPDHLPP |
8.00
|
-3.63 |
-4.74 |
|
STPAKPPQ |
11.91
|
-3.01 |
-4.12 |
| Q12446 |
RPVPPPPP |
4.61
|
-7.92 |
-9.03 |
|
RLPAPPPP |
5.14
|
-8.36 |
-9.47 |
|
PPPQMPAT |
5.89
|
-4.80 |
-5.91 |
| P08018 |
GPPPRLPS |
8.02
|
-3.39 |
-4.50 |
|
APRRPLST |
10.35
|
-4.59 |
-5.70 |
|
PPPRLPSD |
11.38
|
-4.08 |
-5.19 |
| P39969 |
LPPQPGSK |
3.96
|
-6.22 |
-7.33 |
|
LSPIPSPT |
6.83
|
-4.71 |
-5.82 |
|
RRAPKPPS |
8.09
|
-5.97 |
-7.08 |
| Q03790 |
FPSAPQPL |
8.06
|
-4.69 |
-5.80 |
|
KPTATPSP |
8.79
|
-2.93 |
-4.04 |
|
LNGFPSAP |
9.29
|
-4.60 |
-5.71 |
| P41809 |
SPSAPVAV |
8.76
|
-4.36 |
-5.47 |
|
SPSAPVAI |
8.86
|
-3.63 |
-4.74 |
|
SPSAPAAI |
9.03
|
-3.33 |
-4.44 |
| Q05080 |
RQKPDKPR |
10.42
|
-5.26 |
-6.37 |
|
KPDKPRPI |
12.48
|
-5.98 |
-7.09 |
|
QKPDKPRP |
13.66
|
-6.52 |
-7.63 |
| P25344 |
NTPGPSPN |
10.49
|
-2.63 |
-3.74 |
|
ANTPGPSP |
11.20
|
-2.55 |
-3.66 |
| P53297 |
MPFQPQPM |
5.52
|
-5.61 |
-6.72 |
|
MYMPFQPQ |
7.68
|
-5.43 |
-6.54 |
|
SMPQMMPV |
8.56
|
-4.00 |
-5.11 |
| P22147 |
MSIPPPAP |
7.60
|
-6.25 |
-7.36 |
|
SFPPPPPM |
7.75
|
-5.68 |
-6.79 |
|
SIPPPAPH |
8.31
|
-4.28 |
-5.39 |
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