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Matrix information:
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ADAN-name: SHO1_1QCF-12.PDB
Scoring matrix: SHO1_1QCF-12_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.74
Foldx random average score for Saccharomyces cerevisiae: 15.325 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 2101
Proteins considered as fragments or having weird amino acids: 230
Total scanned proteins: 5078
Total fragments: 2181479
Proteins after random average filtering: 5078
Total fragments: 1117637
Proteins after disorder filtering: 3313
Total fragments: 90633
Proteins after pattern filtering: 1570
Total fragments: 8853
Proteins after MINT filtering: 24
Total fragments: 321 ROC parameters:
TPR= 0.429
FPR= 0.308
ACC= 0.689
SPC= 0.692
MCC= 0.027 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
12.74
|
-1.06 |
0.00 |
| Best peptides |
RRIPRRRR |
0.00
|
-4.53 |
-3.47 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
SKPLPLTP |
5.62
|
-3.37 |
-2.31 |
| Q06604 |
PRMPSRGR |
5.35
|
-7.08 |
-6.02 |
|
PSPPAKRI |
5.91
|
-5.66 |
-4.60 |
|
SSPPPLPT |
6.28
|
-4.62 |
-3.56 |
| P24583 |
LPPQPRKH |
6.73
|
-5.84 |
-4.78 |
|
RANAPLPP |
8.82
|
-2.14 |
-1.08 |
|
PLPPQPRK |
13.59
|
-6.85 |
-5.79 |
| Q06412 |
KPPPPLST |
7.67
|
-3.71 |
-2.65 |
|
PPPPPLLY |
7.90
|
-4.15 |
-3.09 |
|
PPPPLLYS |
8.08
|
-3.68 |
-2.62 |
| P40036 |
LPTTPGIR |
12.76
|
-2.03 |
-0.97 |
|
SKSLPTTP |
12.76
|
-2.42 |
-1.36 |
|
PTTPGIRS |
12.86
|
-4.02 |
-2.96 |
| P09620 |
SNPISKPS |
7.47
|
-4.23 |
-3.17 |
|
PSNIPQMH |
8.53
|
-3.31 |
-2.25 |
|
VPDPSNIP |
13.18
|
-2.13 |
-1.07 |
| P13186 |
SYVPNRVP |
6.09
|
-6.58 |
-5.52 |
|
PIPAALPP |
7.89
|
-3.52 |
-2.46 |
|
QNNIPLTP |
8.51
|
-2.30 |
-1.24 |
| P32334 |
PSSPTTTD |
14.57
|
-2.29 |
-1.23 |
| P39083 |
PATPSNVS |
11.63
|
-3.41 |
-2.35 |
|
LQSPATPS |
14.20
|
-3.01 |
-1.95 |
| P38753 |
PVMPPQRQ |
5.90
|
-6.35 |
-5.29 |
|
PYPSNLPI |
7.47
|
-2.41 |
-1.35 |
|
NLPIQHPT |
7.51
|
-5.76 |
-4.70 |
| Q08229 |
PTIPPRSK |
3.49
|
-8.20 |
-7.14 |
|
LPTPVQPG |
10.14
|
-3.84 |
-2.78 |
|
TPVQPGGH |
11.83
|
-2.63 |
-1.57 |
| Q00246 |
EKNLPRLP |
6.11
|
-4.53 |
-3.47 |
|
SSNLPESP |
11.32
|
0.91 |
1.97 |
|
KNLPRLPT |
14.15
|
-4.81 |
-3.75 |
| P32448 |
TDSPQLPS |
9.11
|
-2.04 |
-0.98 |
|
PRVPTDSP |
10.17
|
-3.34 |
-2.28 |
|
PTDSPQLP |
10.58
|
-2.56 |
-1.50 |
| Q04439 |
GSPSELPL |
7.36
|
-3.74 |
-2.68 |
|
PTPPQNRD |
7.77
|
-5.46 |
-4.40 |
|
PPPSSKPK |
8.38
|
-3.95 |
-2.89 |
| P35197 |
SRPDHLPP |
5.34
|
-4.72 |
-3.66 |
|
GSTPAKPP |
8.71
|
-4.81 |
-3.75 |
|
FGSTPAKP |
11.40
|
-1.83 |
-0.77 |
| Q12446 |
PPPPPRRG |
4.60
|
-8.55 |
-7.49 |
|
NRPLPQLP |
6.39
|
-5.21 |
-4.15 |
|
PPPPPHRH |
6.44
|
-6.41 |
-5.35 |
| P08018 |
DGPPPRLP |
5.63
|
-6.09 |
-5.03 |
|
GPPPRLPS |
7.17
|
-4.27 |
-3.21 |
|
TRPNVAPH |
9.32
|
-3.63 |
-2.57 |
| P39969 |
PKPPSYPS |
7.02
|
-4.39 |
-3.33 |
|
PKSPLLNN |
8.09
|
-2.03 |
-0.97 |
|
VSPRRAPK |
8.21
|
-4.40 |
-3.34 |
| Q03790 |
ATPSPFRP |
5.76
|
-4.37 |
-3.31 |
|
FPSAPQPL |
10.75
|
-2.80 |
-1.74 |
|
GKPTATPS |
11.99
|
-3.19 |
-2.13 |
| P41809 |
PYPSPNSY |
9.22
|
-2.26 |
-1.20 |
|
PSVPVAVS |
9.78
|
-4.45 |
-3.39 |
|
TSSPSAPV |
10.41
|
-2.96 |
-1.90 |
| Q05080 |
KPDKPRPI |
8.99
|
-4.87 |
-3.81 |
|
QKPDKPRP |
12.10
|
-5.87 |
-4.81 |
|
RQKPDKPR |
12.70
|
-5.13 |
-4.07 |
| P25344 |
PGPSPNEA |
10.31
|
-1.74 |
-0.68 |
| P53297 |
GNISPHVP |
7.40
|
-6.14 |
-5.08 |
|
MYMPFQPQ |
7.62
|
-5.77 |
-4.71 |
|
GAPEGKPP |
8.13
|
-4.64 |
-3.58 |
| P22147 |
GQPISFPP |
7.09
|
-4.44 |
-3.38 |
|
DEIPKGEP |
8.13
|
-4.66 |
-3.60 |
|
SIPPPAPH |
8.20
|
-4.70 |
-3.64 |
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