ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1OV32-27.PDB
Scoring matrix: SDC25_1OV32-27_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAAA
Foldx wt ligand score: 12.67
Foldx random average score for Saccharomyces cerevisiae: 12.860

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3206298
Proteins after random average filtering: 7178
 Total fragments: 1906791
Proteins after disorder filtering: 4673
 Total fragments: 127981
Proteins after pattern filtering: 2330
 Total fragments: 21358
Proteins after MINT filtering: 2
 Total fragments: 57


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAAA

12.67

-1.31

0.00

Best peptides

ENEPEDYRK

0.00

1.04

2.35

         
Interactors      
P40450

PPLPDLFKT

6.23

-5.07

-3.76

PPPPPPPLP

6.64

-7.44

-6.13

PPPPPLPES

7.39

-6.43

-5.12

Q08601

PGPPPMAYN

6.32

-6.41

-5.10

PMAPPPNQQ

8.54

-4.53

-3.22

PPGPPPMAY

8.62

-6.46

-5.15

 


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