ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1OV32-12.PDB
Scoring matrix: SDC25_1OV32-12_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 10.38
Foldx random average score for Saccharomyces cerevisiae: 8.284

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3213476
Proteins after random average filtering: 7178
 Total fragments: 1323072
Proteins after disorder filtering: 4650
 Total fragments: 89854
Proteins after pattern filtering: 2236
 Total fragments: 13442
Proteins after MINT filtering: 2
 Total fragments: 43


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

10.38

-0.25

0.00

Best peptides

WWWCEWIK

0.00

0.75

1.00

         
Interactors      
P40450

GAVPPPPP

5.65

-4.27

-4.02

QLPPPPPP

6.04

-4.47

-4.22

AVPPPPPP

6.09

-3.42

-3.17

Q08601

YAPPPGPP

6.43

-2.82

-2.57

PGPPPMAY

6.53

-4.43

-4.18

GYQRPMAP

6.90

-2.89

-2.64

 


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