ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1JO8-5.PDB
Scoring matrix: SDC25_1JO8-5_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 15.34
Foldx random average score for Saccharomyces cerevisiae: 15.587

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199120
Proteins after random average filtering: 7178
 Total fragments: 2018911
Proteins after disorder filtering: 4638
 Total fragments: 137241
Proteins after pattern filtering: 2304
 Total fragments: 21417
Proteins after MINT filtering: 2
 Total fragments: 58


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

15.34

3.88

0.00

Best peptides

IEDEDFWDHF

0.00

3.86

-0.02

         
Interactors      
P40450

LVTPPAPPLP

9.35

-4.19

-8.07

LPQLPPPPPP

9.71

-6.21

-10.09

HDLVTPPAPP

10.50

-2.51

-6.39

Q08601

NNGYQRPMAP

10.37

-0.56

-4.44

PMAYNRPVYP

10.72

-1.96

-5.84

PPPGPPPMAY

10.98

-4.46

-8.34

 


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