ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1JO8-29.PDB
Scoring matrix: SDC25_1JO8-29_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.47
Foldx random average score for Saccharomyces cerevisiae: 12.292

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199120
Proteins after random average filtering: 7176
 Total fragments: 1583633
Proteins after disorder filtering: 4374
 Total fragments: 63516
Proteins after pattern filtering: 2107
 Total fragments: 11540
Proteins after MINT filtering: 2
 Total fragments: 36


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.47

-0.04

0.00

Best peptides

EFPPWHPDME

0.00

-5.62

-5.58

         
Interactors      
P40450

PAPPPLPDLF

7.75

-7.55

-7.50

PPLPESLSMN

7.86

-7.13

-7.09

APPPLPDLFK

8.68

-6.92

-6.88

Q08601

APPPGPPPMA

10.59

-7.41

-7.37

PMAYNRPVYP

11.07

-4.15

-4.11

YAPPPGPPPM

11.34

-5.11

-5.07

 


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