ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1JO8-18.PDB
Scoring matrix: SDC25_1JO8-18_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 15.74
Foldx random average score for Saccharomyces cerevisiae: 15.573

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7178
 Total fragments: 3199120
Proteins after random average filtering: 7178
 Total fragments: 1808154
Proteins after disorder filtering: 4655
 Total fragments: 122287
Proteins after pattern filtering: 2263
 Total fragments: 16615
Proteins after MINT filtering: 2
 Total fragments: 37


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

15.74

1.78

0.00

Best peptides

FDPIPSERMW

0.00

4.65

2.87

         
Interactors      
P40450

PPPPPPPLPE

11.20

-3.92

-5.70

PPPLPESLSM

11.27

-2.88

-4.66

PPLPESLSMN

11.40

0.18

-1.60

Q08601

YAPPPGPPPM

10.40

-3.06

-4.84

APPPGPPPMA

13.10

-3.37

-5.15

QRPMAPPPNQ

13.52

-6.12

-7.90

 


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